Journal of the Korea Academia-Industrial cooperation Society (한국산학기술학회논문지)

The Korea Academia-Industrial cooperation Society (한국산학기술학회)
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A study of calculate a time to peak enhancement of contrast level by using blood flow

혈류에 의한 조영제 peak time의 산출에 관한 연구

  • 최관우 (서울아산병원 영상의학과) ;
  • 손순룡 (서울아산병원 영상의학과) ;
  • 이호범 (서울아산병원 영상의학과)
  • Received : 2013.02.12
  • Accepted : 2013.05.09
  • Published : 2013.05.31
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Abstract

This study attempt to develope and suggest a new, minimize side effects process for calculate a time to peak enhancement of contrast level by using blood flow instead of current mathematical process. We conducted a studies 127 patients who performed the CE MRA by using test-contrast inject way. We used measurements of a contrast inflow time and time to peak enhancement of contrast level of each cerebrovascular branch for similarity of witch cerebrovascular branch calculate a time to peak enhancement of contrast level by using blood flow in image compared with calculation a time to peak enhancement of contrast level by using current mathematical process after contrast enhancement. In this study, confidence interval were used if the variable is continuous variable; there is differences between 4 groups exist but in group 1, there is no difference with time in peak enhancement of contrast level by using mathematical method to inflow time in sinus sigmoideus. it was significant statistically, in addition there was significant low heterogeneity in Bland Altman plot. Thus, apply a new calculate a time to peak enhancement of contrast level by using blood flow method will minimize damage caused by side effect, maintain quality of image, easy and fast access. It should provide a space for the exchange of current calculate a time to peak enhancement of contrast level by using mathematical process.

본 연구는 혈류에 의한 조영제 peak time을 산출하는 새로운 방법을 개발하여 기존의 수식에 의한 부작용을 최소화 하고, 대체할 수 있는 새로운 검사법을 제시하고자 하였다. 시험적조영제주입법을 이용하여 CE MRA를 검사한 환자 127명을 대상으로, 기존의 수식에 의해 산출된 조영제 peak time이 조영제 주입 후 혈류에 의한 영상화 범위의 어느 뇌혈관 측정값과 일치하는지 각 뇌혈관의 조영제 inflow time과 peak time을 측정하였다. 연구결과, 유의수준 0.05에 대한 4개의 집단 간 차이가 존재하였으나 집단 1에서 수식에 의해 산출된 조영제 peak time과 S상 정맥동의 조영제 inflow time이 통계적으로 유의한 차이가 없어 일치하였으며, Bland Altman plot를 시행한 결과 일치도가 상당히 높은 것을 확인할 수 있었다. 따라서 본 연구의 혈류에 의한 새로운 방법을 적용한다면, 부작용 가능성을 최소화하고, 영상의 질은 유지하면서, 쉽고 빠르게 적용할 수 있어, 기존의 수식에 의해 산출된 조영제 peak time을 대체 할 수 있으리라 사료된다.

Keywords

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