DOI QR코드

DOI QR Code

Carcinosarcoma of the Stomach: A Case Report

  • Choi, Kyeong Woon (Department of Surgery, Inje University Paik Hospital, Inje University College of Medicine) ;
  • Lee, Woo Yong (Department of Surgery, Inje University Paik Hospital, Inje University College of Medicine) ;
  • Hong, Seong Woo (Department of Surgery, Inje University Paik Hospital, Inje University College of Medicine) ;
  • Chang, Yeo Goo (Department of Surgery, Inje University Paik Hospital, Inje University College of Medicine) ;
  • Lee, Byungmo (Department of Surgery, Inje University Paik Hospital, Inje University College of Medicine) ;
  • Lee, Hye Kyung (Department of Pathology, Inje University Paik Hospital, Inje University College of Medicine)
  • 투고 : 2012.08.29
  • 심사 : 2012.12.01
  • 발행 : 2013.03.30

초록

Carcinosarcoma is a rare malignant, biphasic tumor comprised of carcinoma and sarcoma components. In the gastrointestinal tract, carcinosarcoma is most frequently seen in the esophagus and rarely in the stomach. We report a 51-year-old female patient with 2-month-history of epigastric pain and dyspepsia. Endoscopic finding revealed a huge ulcerative lesion that infiltrated from the antrum to the mid-body. An endoscopically taken biopsy revealed poorly differentiated malignant round cell neoplasm. After the palliative subtotal gastrectomy, immunohistochemical studies showed two positive reactions for the epithelial marker and mesenchymal marker. Based on the above findings, the patient was diagnosed with gastric carcinosarcoma. The immunohistochemical analysis is a critical method in making an accurate diagnosis of carcinosarcoma.

키워드

참고문헌

  1. Bansal M, Kaneko M, Gordon RE. Carcinosarcoma and separate carcinoid tumor of the stomach. A case report with light and electron microscopic studies. Cancer 1982;50:1876-1881. https://doi.org/10.1002/1097-0142(19821101)50:9<1876::AID-CNCR2820500937>3.0.CO;2-7
  2. Tsuneyama K, Sasaki M, Sabit A, Yokoi K, Arano Y, Imai T, et al. A case report of gastric carcinosarcoma with rhabdomyosarcomatous and neuroendocrinal differentiation. Pathol Res Pract 1999;195:93-97. https://doi.org/10.1016/S0344-0338(99)80077-6
  3. Kitamura S. Study on carcinosarcoma of stomach. Gann 1950;41:15-26.
  4. Tanimura H, Furuta M. Carcinosarcoma of the stomach. Am J Surg 1967;113:702-709. https://doi.org/10.1016/0002-9610(67)90325-X
  5. Quekenstadt H, ed. Uber Karzinosarkome Leipzig, 1904.
  6. Kayaselcuk F, Tuncer I, ToyganozuuY, Bal N, Ozgur G. Carcinosarcoma of the stomach. Pathol Oncol Res 2002;8:275-277. https://doi.org/10.1007/BF03036745
  7. Kim BB, Choi WJ, Park HR. Carcinosarcoma of the stomach. J Korean Surg Soc 1991;40:113-120.
  8. Teramachi K, Kanomata N, Hasebe T, Ishii G, Sugito M, Ochiai A. Carcinosarcoma (pure endocrine cell carcinoma with sarcoma components) of the stomach. Pathol Int 2003;53:552-556. https://doi.org/10.1046/j.1440-1827.2003.01508.x
  9. Kawabata Y, Nakai T, Ooba K, Okumura T, Matsuura Y, Miyazaki Y, et al. A case report of carcinosarcoma of the stomach (in Japanese). Jpn J Gastroenterol Surg 1993;26:2189-2193. https://doi.org/10.5833/jjgs.26.2189
  10. Sato Y, Shimozono T, Kawano S, Toyoda K, Onoe K, Asada Y, et al. Gastric carcinosarcoma, coexistence of adenosquamous carcinoma and rhabdomyosarcoma: a case report. Histopathology 2001;39:543-544. https://doi.org/10.1046/j.1365-2559.2001.1301e.x
  11. He YC, Cao J, Chen JW, Pan DY, Zhou YK. Influence of methionine/ valine-depleted enteral nutrition on nucleic acid and protein metabolism in tumor-bearing rats. World J Gastroenterol 2003;9:771-774. https://doi.org/10.3748/wjg.v9.i4.771

피인용 문헌

  1. A case of gastric carcinosarcoma with distant metastasis for which chemotherapy with S-1 plus cisplatin was transiently effective vol.3, pp.4, 2013, https://doi.org/10.1007/s13691-014-0157-7
  2. Carcinosarcomes gynécologiques : revue générale et principes de prise en charge vol.101, pp.7, 2013, https://doi.org/10.1684/bdc.2014.1937
  3. Postsurgical radiation therapy for gastric carcinosarcoma with c-kit expression: A case report vol.21, pp.9, 2015, https://doi.org/10.3748/wjg.v21.i9.2830
  4. Multidisciplinary therapy for granulocyte-colony-stimulating factor producing carcinosarcoma of the esophagus: report of a case vol.3, pp.8, 2013, https://doi.org/10.1002/ccr3.295
  5. Mesenchymal Stem Cells: Miraculous Healers or Dormant Killers? vol.14, pp.5, 2013, https://doi.org/10.1007/s12015-018-9824-y
  6. True Gastric Carcinosarcoma with Rhabdomyosarcomatous Differentiation vol.52, pp.3, 2013, https://doi.org/10.5833/jjgs.2017.0151
  7. Adenocarcinosarcoma at the esophagogastric junction with long esophageal invasion: a case report vol.6, pp.1, 2013, https://doi.org/10.1186/s40792-020-0785-4
  8. Carcinosarcoma of the Stomach vol.25, pp.2, 2013, https://doi.org/10.1007/s11605-020-04668-6
  9. Carcinosarcoma of the stomach with alpha-fetoprotein-producing hepatoid adenocarcinoma: an unexpected combination of two rare subtypes of gastric cancer in one tumor vol.49, pp.8, 2013, https://doi.org/10.1177/03000605211037422