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Addition of Hydroxyapatite to Toothpaste and Its Effect to Dentin Remineralization

  • Sadiasa, Alexander (Department of Biomedical Engineering and Materials, Soonchunhyang University) ;
  • Jang, Dong-Woo (Department of Biomedical Engineering and Materials, Soonchunhyang University) ;
  • Nath, Subrata Deb (Department of Biomedical Engineering and Materials, Soonchunhyang University) ;
  • Seo, Hyung Seok (Department of Exercise Prescription, Konyang University) ;
  • Yang, Hyn Mo (Department of Biomedical Engineering and Materials, Soonchunhyang University) ;
  • Lee, Byong Taek (Department of Biomedical Engineering and Materials, Soonchunhyang University)
  • 투고 : 2012.12.20
  • 심사 : 2013.02.26
  • 발행 : 2013.03.27

초록

In this study, hydroxyapatite (HAp) was incorporated into toothpaste and its effect on the remineralization and restoration of dental enamel was evaluated. Different sets of toothpaste were incorporated with HAp levels of 0%, 5%, 10 %, and 15 %. The filler particles of the resulting toothpaste samples were observed via SEM and XRD and compared with compositions of several commercially available toothpastes, showing that the HAp was successfully incorporated into the toothpaste samples. Different sets of human enamel were inflicted with lesions and then treated with the different fabricated toothpaste samples for five minutes three times a day for seven days. During the treatment, the teeth were subjected to demineralization and remineralization cycles to simulate the effect of natural saliva. The surface of the enamel samples were observed using SEM before and after one week of treatment, showing the formation of HAp layers on the surfaces of the enamel samples. The effect of the toothpaste on the lesions was observed using an inverted light microscope and the lesion depth was found to decrease as the concentration of HAp in the toothpaste used increased. HAp was successfully incorporated in the toothpaste and its presence was found to lessen lesion depths and improve tooth remineralization.

키워드

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피인용 문헌

  1. In Vitro and In Vivo Evaluation of Composite Scaffold of BCP, Bioglass and Gelatin for Bone Tissue Engineering vol.24, pp.6, 2014, https://doi.org/10.3740/MRSK.2014.24.6.310