Journal of Acupuncture Research

Korean Acupuncture & Moxibustion Medicine Society (대한침구의학회)
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Review on Clinical Trials of Chemotherapy Induced Toxicity with Acupuncture in PubMed Database

PubMed 검색을 통한 항암화학요법 부작용 관련 침 임상시험 현황 고찰

  • Kim, Jong Yoon (Department of Acupuncture & Moxibustion Medicine, College of Korean Medicine, Kyung Hee University) ;
  • Kim, Jin Youp (Department of Acupuncture & Moxibustion Medicine, College of Korean Medicine, Kyung Hee University) ;
  • Kim, Nam Sik (Department of Acupuncture & Moxibustion Medicine, College of Korean Medicine, Kyung Hee University) ;
  • Kim, So Jung (Department of Acupuncture & Moxibustion Medicine, College of Korean Medicine, Kyung Hee University) ;
  • Oyungerel, Munkhgerel (Department of Acupuncture & Moxibustion Medicine, College of Korean Medicine, Kyung Hee University) ;
  • Kim, Yong Suk (Department of Acupuncture & Moxibustion Medicine, College of Korean Medicine, Kyung Hee University) ;
  • Choi, Do Young (Department of Acupuncture & Moxibustion Medicine, College of Korean Medicine, Kyung Hee University) ;
  • Nam, Sang Soo (Department of Acupuncture & Moxibustion Medicine, College of Korean Medicine, Kyung Hee University)
  • 김종윤 (경희대학교 한의과대학 침구의학교실) ;
  • 김진엽 (경희대학교 한의과대학 침구의학교실) ;
  • 김남식 (경희대학교 한의과대학 침구의학교실) ;
  • 김소정 (경희대학교 한의과대학 침구의학교실) ;
  • 뭉흐게렐 (경희대학교 한의과대학 침구의학교실) ;
  • 김용석 (경희대학교 한의과대학 침구의학교실) ;
  • 최도영 (경희대학교 한의과대학 침구의학교실) ;
  • 남상수 (경희대학교 한의과대학 침구의학교실)
  • Received : 2013.03.11
  • Accepted : 2013.03.29
  • Published : 2013.04.20
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Abstract

Objectives : The purpose of this study is to review of Clinical trials related to the treatment of chemotherapy induced-toxicity by acupuncture therapy. Methods : We searched PubMed by using word of "chemotherapy induced, acupuncture" (Limits : Full text available, 10 years, Clinical trials, Humans, English). We analyzed 15 research paper and examined published journals, years, countries, topic, study design, their results, interventions, participants and instruments of assessment. Results : Eleven journals with fifteen papers were searched. These papers were published in USA, Germany, etc. On the topic of these clinical trials, seven of them were about nausea(vomiting), two about peripheral neuropathy, two about hot flash, two about arthralgia and one about neutropenia, one about fatigue. Six of these studies were single blinded, randomized controlled trial. Twelve studies reported significant effect. The median for number of final participants was 35.5 persons. Assessment for outcomes were versatile questionnaire, nerve conduction studies, WBC, ANC, G-CSF examination, etc. Conclusions : Their median for impact factor was 3.650 and average modified Jadad score of six RCTs was 4.33. In order to provide appropriate evidence regarding the effectiveness of acupuncture in treatment for chemotherapy-induced toxicity, more rigorous and well-designed studies are necessary.

Keywords

References

  1. Powis G, Hacker MP. The toxicity of anticancer drugs. New York : Pergamon Press. 1990 : 1-8.
  2. Rozencweig M, Von Hoff DD, Staquet MJ et al. Animal toxicology for early clinical trials with anticancer agents. Cancer Clin Trials. 1981 ; 4(1) : 21-8.
  3. Windebank AJ, Grisold W. Chemotherapy-induced neuropathy. J Peripher Nerv Syst. 2008 ; 13(1) : 27-46. https://doi.org/10.1111/j.1529-8027.2008.00156.x
  4. Nam DW, Lee JD, Choi DY. Study trends on acupuncture treatment of cancer. The Journal of Korean Acupuncture & Moxibustion Society. 2007 ; 24(1) : 209-17.
  5. Brunelli B, Gorson KC. The use of complementary and alternative medicines by patients with peripheral neuropathy. J Neurol Sci. 2004 ; 15 ; 218(1-2) : 59-66. https://doi.org/10.1016/j.jns.2003.10.013
  6. Yeh CH, Chien LC, Chiang YC, Lin SW, Huang CK, Ren D. Reduction in nausea and vomiting in children undergoing cancer chemotherapy by either appropriate or sham auricular acupuncture points with standard care. Journal of Alternative & Complementary Medicine. 2012 ; 18(4) : 334-40. https://doi.org/10.1089/acm.2011.0102
  7. Schroeder S, Meyer-Hamme G, Epplee S. Acupuncture for chemotherapy-induced peripheral neuropathy (CIPN): a pilot study using neurography. Acupunct Med. 2012 ; 30(1) : 4-7. https://doi.org/10.1136/acupmed-2011-010034
  8. Donald GK, Tobin I, Stringer J. Evaluation of acupuncture in the management of chemotherapy- induced peripheral neuropathy. Acupunct Med. 2011 ; 29(3) : 230-3. https://doi.org/10.1136/acupmed.2011.010025
  9. Hani A, Jiang ML, Adel G, Francesco P, Mark A. Acupuncture for the alleviation of hot flashes in men treated with androgen ablation therapy. Radiation Oncology Biol Phys. 2011 ; 79(5) : 1358-63. https://doi.org/10.1016/j.ijrobp.2010.01.025
  10. Katherine DC, Jillian LC, Heather G et al. Randomized, blinded, sham-controlled trial of acupuncture for the management of aromatase inhibitorassociated joint symptoms in women with earlystage breast cancer. Journal of Clinical Oncology. 2010 ; 28(7) : 1154-60. https://doi.org/10.1200/JCO.2009.23.4708
  11. James JM, Deborah WB, Carrie S et al. Feasibility trial of electroacupuncture for aromatase inhibitorrelated arthralgia in breast cancer survivors. Integr Cancer Ther. 2009 ; 8(2) : 123-9. https://doi.org/10.1177/1534735409332903
  12. Lu W, Ursula AM, Anne DG et al. Acupuncture for chemotherapy-induced neutropenia in patients with gynecologic malignancies: a pilot randomized, sham-controlled clinical trial. The Journal of Alternative and Complementary Medicine. 2009 ; 15(7) : 745-53. https://doi.org/10.1089/acm.2008.0589
  13. You Q, Yu H, Wu D, Zhang Y, Zheng J, Peng C. Vitamin B6 points PC6 injection during acupuncture can relieve nausea and vomiting in patients with ovarian cancer. International Journal of Gynecological Cancer. 2009 ; 19(4) : 567-71. https://doi.org/10.1111/IGC.0b013e31819d8b48
  14. Gottschling S, Reindl TK, Meyer S et al. Acupuncture to alleviate chemotherapy-induced nausea and vomiting in pediatric oncology - a randomized multicenter crossover pilot trial. Klin Padiatr. 2008 ; 220(6) : 365-70. https://doi.org/10.1055/s-0028-1086039
  15. Hervik J, Mjaland O. Acupuncture for the treatment of hot flashes in breast cancer patients, a randomized, controlled trial. Breast Cancer Research and Treatment. 2009 ; 116(2) : 311-6. https://doi.org/10.1007/s10549-008-0210-3
  16. Molassiotis A, Sylt P, Digginst H. The management of cancer-related fatigue after chemotherapy with acupuncture and acupressure: a randomised controlled trial. Complement Ther Med. 2007(4) ; 15(4) : 228-37. https://doi.org/10.1016/j.ctim.2006.09.009
  17. Choo SP, Kong KH, Lim WT, Gao F, Chua K, Leong SS. Electroacupuncture for refractory acute emesis caused by chemotherapy. The Journal of Alternative and Complementary Medicine. 2006 ; 12(10) : 963-9. https://doi.org/10.1089/acm.2006.12.963
  18. Melchart D, Ihbe-Heffinger A, Leps B, von Schilling C, Linde K. Acupuncture and acupressure for the prevention of chemotherapy-induced nausea; a randomised cross- over pilot study. Support Care Cancer. 2006 ; 14(8) : 878-82. https://doi.org/10.1007/s00520-006-0028-7
  19. Tobias KR, Wilhelm G, Reinhard H et al. Acupuncture against chemotherapy-induced nausea and vomiting in pediatric oncology. Interim results of a multicenter crossover study. Support Care Cancer. 2006 ; 14(2) : 172-6. https://doi.org/10.1007/s00520-005-0846-z
  20. Roscoe JA, Matteson SE, Morrow GR et al. Acustimulation wrist bands are not effective for the control of chemotherapy-induced nausea in women with breast cancer. J Pain Symptom Manage. 2005 ; 29(4) : 376-84. https://doi.org/10.1016/j.jpainsymman.2004.07.007
  21. Son JG, Kim YI, Lee PS. 2003 Technology industry information analysis 'Anti Cancer Drugs'. Korea Institute of Science and Technology Information. 2003.
  22. Min YD, Park YH, Baek GE, Lee JS. What is cancer. Gwangju : Chosun University Publishing Department. 2003 : 196-250.
  23. Kaley TJ, Deangelis LM. Therapy of chemotherapy- induced peripheral neuropathy. Br J Haematol. 2009 ; 145(1) : 3-14. https://doi.org/10.1111/j.1365-2141.2008.07558.x
  24. Baquiran DC. Lippincott's cancer chemotherapy handbook 2nd ed. Philadelphia : Lippincott. 2001 : 129.
  25. Kim SY, Park BJ. Evidence based healthcare. Seoul : Korea Medical. 2009 : 37.
  26. Jadad AR, Moore RA, Carrol D et al. Assessing the quality of reports of randomized clinical trials: is blinding necessary?. Control Clin Trials. 1996 ; 17(1) : 1-12. https://doi.org/10.1016/0197-2456(95)00134-4