참고문헌
- Kim HS, Parajuli SP, Yeum CH, Park JS, Jeong HS, So I, Kim KW, Jun JY, Choi S. Effects of ginseng total saponins on pacemaker currents of interstitial cells of Cajal from the small intestine of mice. Biol Pharm Bull 2007;30:2037-2042. https://doi.org/10.1248/bpb.30.2037
- Kim BJ, Park EJ, Lee JH, Jeon JH, Kim SJ, So I. Suppression of transient receptor potential melastatin 7 channel induces cell death in gastric cancer. Cancer Sci 2008;99:2502-2509. https://doi.org/10.1111/j.1349-7006.2008.00982.x
- Guilbert A, Gautier M, Dhennin-Duthille I, Haren N, Sevestre H, Ouadid-Ahidouch H. Evidence that TRPM7 is required for breast cancer cell proliferation. Am J Physiol Cell Physiol 2009;297:C493-C502. https://doi.org/10.1152/ajpcell.00624.2008
- Clapham DE. TRP channels as cellular sensors. Nature 2003;426:517-524. https://doi.org/10.1038/nature02196
- Nadler MJ, Hermosura MC, Inabe K, Perraud AL, Zhu Q, Stokes AJ, Kurosaki T, Kinet JP, Penner R, Scharenberg AM et al. LTRPC7 is a Mg.ATP-regulated divalent cation channel required for cell viability. Nature 2001;411:590-595. https://doi.org/10.1038/35079092
- Runnels LW, Yue L, Clapham DE. TRP-PLIK, a bifunctional protein with kinase and ion channel activities. Science 2001;291:1043-1047. https://doi.org/10.1126/science.1058519
- Jiang J, Li MH, Inoue K, Chu XP, Seeds J, Xiong ZG. Transient receptor potential melastatin 7-like current in human head and neck carcinoma cells: role in cell proliferation. Cancer Res 2007;67:10929-10938. https://doi.org/10.1158/0008-5472.CAN-07-1121
- Jin J, Desai BN, Navarro B, Donovan A, Andrews NC, Clapham DE. Deletion of Trpm7 disrupts embryonic development and thymopoiesis without altering Mg2+homeostasis. Science 2008;322:756-760. https://doi.org/10.1126/science.1163493
- Schmitz C, Perraud AL, Johnson CO, Inabe K, Smith MK, Penner R, Kurosaki T, Fleig A, Scharenberg AM. Regulation of vertebrate cellular Mg2+ homeostasis by TRPM7. Cell 2003;114:191-200. https://doi.org/10.1016/S0092-8674(03)00556-7
- Kim BJ, Nah SY, Jeon JH, So I, Kim SJ. Transient receptor potential melastatin 7 channels are involved in ginsenoside Rg3-induced apoptosis in gastric cancer cells. Basic Clin Pharmacol Toxicol 2011;109:233-239. https://doi.org/10.1111/j.1742-7843.2011.00706.x
- Han S, Kim JS, Jung BK, Han SE, Nam JH, Kwon YK, Nah SY, Kim BJ. Effects of ginsenoside on pacemaker potentials of cultured interstitial cells of Cajal clusters from the small intestine of mice. Mol Cells 2012;33:243-249. https://doi.org/10.1007/s10059-012-2204-6
- Nicoletti I, Migliorati G, Pagliacci MC, Grignani F, Riccardi C. A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. J Immunol Methods 1991;139:271-279. https://doi.org/10.1016/0022-1759(91)90198-O
- Wang BJ, Won SJ, Yu ZR, Su CL. Free radical scavenging and apoptotic effects of Cordyceps sinensis fractionated by supercritical carbon dioxide. Food Chem Toxicol 2005;43:543-552. https://doi.org/10.1016/j.fct.2004.12.008
- Hotz MA, Gong J, Traganos F, Darzynkiewicz Z. Flow cytometric detection of apoptosis: comparison of the assays of in situ DNA degradation and chromatin changes. Cytometry 1994;15:237-244. https://doi.org/10.1002/cyto.990150309
- Vermes I, Haanen C, Reutelingsperger C. Flow cytometry of apoptotic cell death. J Immunol Methods 2000;243:167-190. https://doi.org/10.1016/S0022-1759(00)00233-7
- Fleig A, Penner R. Emerging roles of TRPM channels. Novartis Found Symp 2004;258:248-258. https://doi.org/10.1002/0470862580.ch18
- Harteneck C, Plant TD, Schultz G. From worm to man: three subfamilies of TRP channels. Trends Neurosci 2000;23:159-166. https://doi.org/10.1016/S0166-2236(99)01532-5
- Montell C. Physiology, phylogeny, and functions of the TRP superfamily of cation channels. Sci STKE 2001;2001:re1.
- Monteilh-Zoller MK, Hermosura MC, Nadler MJ, Scharenberg AM, Penner R, Fleig A. TRPM7 provides an ion channel mechanism for cellular entry of trace metal ions. J Gen Physiol 2003;121:49-60. https://doi.org/10.1085/jgp.20028740
- Minke B, Cook B. TRP channel proteins and signal transduction. Physiol Rev 2002;82:429-472. https://doi.org/10.1152/physrev.00001.2002
- Hanano T, Hara Y, Shi J, Morita H, Umebayashi C, Mori E, Sumimoto H, Ito Y, Mori Y, Inoue R. Involvement of TRPM7 in cell growth as a spontaneously activated Ca2+ entry pathway in human retinoblastoma cells. J Pharmacol Sci 2004;95:403-419. https://doi.org/10.1254/jphs.FP0040273
- He Y, Yao G, Savoia C, Touyz RM. Transient receptor potential melastatin 7 ion channels regulate magnesium homeostasis in vascular smooth muscle cells: role of angiotensin II. Circ Res 2005;96:207-215. https://doi.org/10.1161/01.RES.0000152967.88472.3e
- Aarts M, Iihara K, Wei WL, Xiong ZG, Arundine M, Cerwinski W, MacDonald JF, Tymianski M. A key role for TRPM7 channels in anoxic neuronal death. Cell 2003;115:863-877. https://doi.org/10.1016/S0092-8674(03)01017-1
- Krapivinsky G, Mochida S, Krapivinsky L, Cibulsky SM, Clapham DE. The TRPM7 ion channel functions in cholinergic synaptic vesicles and affects transmitter release. Neuron 2006;52:485-496. https://doi.org/10.1016/j.neuron.2006.09.033
- Su D, May JM, Koury MJ, Asard H. Human erythrocyte membranes contain a cytochrome b561 that may be involved in extracellular ascorbate recycling. J Biol Chem 2006;281:39852-39859. https://doi.org/10.1074/jbc.M606543200
- Kim BJ, Lim HH, Yang DK, Jun JY, Chang IY, Park CS, So I, Stanfield PR, Kim KW. Melastatin-type transient receptor potential channel 7 is required for intestinal pacemaking activity. Gastroenterology 2005;129:1504-1517. https://doi.org/10.1053/j.gastro.2005.08.016
- Wykes RC, Lee M, Duffy SM, Yang W, Seward EP, Bradding P. Functional transient receptor potential melastatin 7 channels are critical for human mast cell survival. J Immunol 2007;179:4045-4052. https://doi.org/10.4049/jimmunol.179.6.4045
- Abed E, Moreau R. Importance of melastatin-like transient receptor potential 7 and cations (magnesium, calcium) in human osteoblast-like cell proliferation. Cell Prolif 2007;40:849-865. https://doi.org/10.1111/j.1365-2184.2007.00476.x
-
Hong H, Cui CH, Kim JK, Jin FX, Kim SC, Im WT. Enzymatic biotransformation of ginsenoside Rb1 and gypenoside XVII into ginsenosides Rd and F2 by recombinant
${\beta}$ -glucosidase from Flavobacterium johnsoniae. J Ginseng Res 2012;36:418-424. https://doi.org/10.5142/jgr.2012.36.4.418 - Quan LH, Piao JY, Min JW, Kim HB, Kim SR, Yang DU, Yang DC. Biotransformation of ginsenoside Rb1 to prosapogenins, gypenoside XVII, ginsenoside Rd, ginsenoside F2, and compound K by Leuconostoc mesenteroides DC102. J Ginseng Res 2011;35:344-351. https://doi.org/10.5142/jgr.2011.35.3.344
- Sun HS, Jackson MF, Martin LJ, Jansen K, Teves L, Cui H, Kiyonaka S, Mori Y, Jones M, Forder JP et al. Suppression of hippocampal TRPM7 protein prevents delayed neuronal death in brain ischemia. Nat Neurosci 2009;12:1300-1307. https://doi.org/10.1038/nn.2395
- Ye R, Li N, Han J, Kong X, Cao R, Rao Z, Zhao G. Neuroprotective effects of ginsenoside Rd against oxygen-glucose deprivation in cultured hippocampal neurons. Neurosci Res 2009;64:306-310. https://doi.org/10.1016/j.neures.2009.03.016
- Li N, Liu B, Dluzen DE, Jin Y. Protective effects of ginsenoside Rg2 against glutamate-induced neurotoxicity in PC12 cells. J Ethnopharmacol 2007;111:458-463. https://doi.org/10.1016/j.jep.2006.12.015
- Wu J, Jeong HK, Bulin SE, Kwon SW, Park JH, Bezprozvanny I. Ginsenosides protect striatal neurons in a cellular model of Huntington's disease. J Neurosci Res 2009;87:1904-1912. https://doi.org/10.1002/jnr.22017
- Ye R, Zhang X, Kong X, Han J, Yang Q, Zhang Y, Chen Y, Li P, Liu J, Shi M et al. Ginsenoside Rd attenuates mitochondrial dysfunction and sequential apoptosis after transient focal ischemia. Neuroscience 2011;178:169-180. https://doi.org/10.1016/j.neuroscience.2011.01.007
- Ye R, Yang Q, Kong X, Han J, Zhang X, Zhang Y, Li P, Liu J, Shi M, Xiong L, et al. Ginsenoside Rd attenuates early oxidative damage and sequential inflammatory response after transient focal ischemia in rats. Neurochem Int 2011;58:391-398. https://doi.org/10.1016/j.neuint.2010.12.015
- Liu X, Xia J, Wang L, Song Y, Yang J, Yan Y, Ren H, Zhao G. Efficacy and safety of ginsenoside-Rd for acute ischaemic stroke: a randomized, double-blind, placebo-controlled, phase II multicenter trial. Eur J Neurol 2009;16:569-575. https://doi.org/10.1111/j.1468-1331.2009.02534.x
- Zhang Y, Zhou L, Zhang X, Bai J, Shi M, Zhao G. Ginsenoside-Rd attenuates TRPM7 and ASIC1a but promotes ASIC2a expression in rats after focal cerebral ischemia. Neurol Sci 2012;33:1125-1131. https://doi.org/10.1007/s10072-011-0916-6
- Hao M, Wang W, Zhao Y, Zhang R, Wang H. Pharma-cokinetics and tissue distribution of 25-hydroxyprotopanaxadiol, an anti-cancer compound isolated from Panax ginseng, in athymic mice bearing xenografts of human pancreatic tumors. Eur J Drug Metab Pharmacokinet 2011;35:109-113. https://doi.org/10.1007/s13318-010-0022-9
- Li B, Zhao J, Wang CZ, Searle J, He TC, Yuan CS, Du W. Ginsenoside Rh2 induces apoptosis and paraptosis-like cell death in colorectal cancer cells through activation of p53. Cancer Lett 2011;301:185-192. https://doi.org/10.1016/j.canlet.2010.11.015
- He BC, Gao JL, Luo X, Luo J, Shen J, Wang L, Zhou Q, Wang YT, Luu HH, Haydon RC et al. Ginsenoside Rg3 inhibits colorectal tumor growth through the down-regulation of Wnt/b-catenin signaling. Int J Oncol 2011;38:437-445.
피인용 문헌
- New insights into pharmacological tools to TR(i)P cancer up vol.171, pp.10, 2014, https://doi.org/10.1111/bph.12561
- Cellular physiological approach for treatment of gastric cancer vol.20, pp.33, 2014, https://doi.org/10.3748/wjg.v20.i33.11560
- Cellular and Developmental Biology of TRPM7 Channel-Kinase: Implicated Roles in Cancer vol.3, pp.3, 2014, https://doi.org/10.3390/cells3030751
- Studies vol.19, pp.4, 2015, https://doi.org/10.4196/kjpp.2015.19.4.365
- Recent advances in ginseng as cancer therapeutics: a functional and mechanistic overview vol.32, pp.2, 2015, https://doi.org/10.1039/C4NP00080C
- Saponins from Chinese Medicines as Anticancer Agents vol.21, pp.10, 2016, https://doi.org/10.3390/molecules21101326
- Role of TRP ion channels in cancer and tumorigenesis vol.38, pp.3, 2016, https://doi.org/10.1007/s00281-015-0525-1
- Role of TRPM7 in Cancer: Potential as Molecular Biomarker and Therapeutic Target vol.10, pp.2, 2017, https://doi.org/10.3390/ph10020039
- Multi-Dimensional Spectrum-Effect Relationship of the Impact of Chinese Herbal Formula Lichong Shengsui Yin on Ovarian Cancer vol.22, pp.6, 2017, https://doi.org/10.3390/molecules22060979
- Ginsenoside Rd regulates the Akt/mTOR/p70S6K signaling cascade and suppresses angiogenesis and breast tumor growth vol.38, pp.1, 2017, https://doi.org/10.3892/or.2017.5652
- The inhibitory effects of ginsenoside Rd on the human glioma U251 cells and its underlying mechanisms vol.120, pp.3, 2019, https://doi.org/10.1002/jcb.27732
- TRPM7 promotes the epithelial–mesenchymal transition in ovarian cancer through the calcium-related PI3K / AKT oncogenic signaling vol.38, pp.1, 2019, https://doi.org/10.1186/s13046-019-1061-y
- Apoptotic Effects and Involvement of TRPM7 Channels of the Traditional Herbal Medicine, Dangkwisoo-San in Gastric Cancer Cells vol.10, pp.7, 2013, https://doi.org/10.3923/ijp.2014.398.405
- Cholesterol-induced activation of TRPM7 regulates cell proliferation, migration, and viability of human prostate cells vol.1843, pp.9, 2013, https://doi.org/10.1016/j.bbamcr.2014.04.019
- AP-1-Targeted Anti-Inflammatory Activities of the Nanostructured, Self-Assembling S5 Peptide vol.2015, pp.None, 2013, https://doi.org/10.1155/2015/451957
- Ginsenoside Rd attenuates breast cancer metastasis implicating derepressing microRNA-18a-regulated Smad2 expression vol.6, pp.None, 2013, https://doi.org/10.1038/srep33709
- Role of transient receptor potential melastatin type 7 channel in gastric cancer vol.5, pp.2, 2013, https://doi.org/10.1016/j.imr.2016.04.004
- Therapeutic Potential and Cellular Mechanisms of Panax Notoginseng on Prevention of Aging and Cell Senescence-Associated Diseases vol.8, pp.6, 2013, https://doi.org/10.14336/ad.2017.0724
- Characterization of Paenibacillus sp. MBT213 Isolated from Raw Milk and Its Ability to Convert Ginsenoside Rb1 into Ginsenoside Rd from Panax ginseng vol.37, pp.5, 2013, https://doi.org/10.5851/kosfa.2017.37.5.735
- Cytokine modulation in Raw 264.7 macrophages treated with ginseng fermented by Penibacillus MBT213 vol.45, pp.4, 2018, https://doi.org/10.7744/kjoas.20180057
- Recent Advances in Ginsenosides as Potential Therapeutics Against Breast Cancer vol.19, pp.25, 2013, https://doi.org/10.2174/1568026619666191018100848
- Transient Receptor Potential Cation Channels in Cancer Therapy vol.7, pp.12, 2019, https://doi.org/10.3390/medsci7120108
- The Role of Transient Receptor Potential Melastatin 7 (TRPM7) in Cell Viability: A Potential Target to Suppress Breast Cancer Cell Cycle vol.12, pp.1, 2013, https://doi.org/10.3390/cancers12010131
- The role of TRPV1 ion channels in the suppression of gastric cancer development vol.39, pp.1, 2020, https://doi.org/10.1186/s13046-020-01707-7
- The Presence and Distribution of TRPM7 in the Canine Mammary Glands vol.10, pp.3, 2020, https://doi.org/10.3390/ani10030466
- TRPM7 Ion Channel: Oncogenic Roles and Therapeutic Potential in Breast Cancer vol.13, pp.24, 2013, https://doi.org/10.3390/cancers13246322
- Modulators of TRPM7 and its potential as a drug target for brain tumours vol.101, pp.None, 2022, https://doi.org/10.1016/j.ceca.2021.102521