The Korean Journal of Community Living Science (한국지역사회생활과학회지)

The Korean Society of Community Living Science (한국지역사회생활과학회)
권호 표지
DOI QR코드

DOI QR Code

Simulateous Determination for the Contents of Caffeine and Chlorogenic Acid in Coffee Beans

원두커피내 카페인 및 클로로겐산 함량 평가를 위한 동시분석법

  • Received : 2012.08.31
  • Accepted : 2013.02.14
  • Published : 2013.03.30
Download PDF
⟨ Previous Next ⟩

Abstract

Caffeine is an alkaloid of the methylxanthine family known as a central nervous system stimulant, temporarily warding off drowsiness and restoring alertness in humans. There is a recommended upper limits of caffeine for health because a high dose can cause negative effects. Chlorogenic acid is a natural polyphenol compound known to have an antioxidant activity. In this study, the contents of caffeine and chlorogenic acid in coffee beans from different origins(Costa Rica, Indonesia, Vietnam) were determined by using liquid chromatography-tandem mass spectrometry(LC-MS/MS). The experiment offers more selectivity and sensitivity for those compounds compared with conventional methods such as UV/VIS spectrophotometry. The average concentrations of caffeine and chlorogenic acid in coffee beans origined in Costa Rica were 15.05 mg/g and 5.33 mg/g respectively. In the case of coffee beans origined in Indonesia, the average concentrations were 13.10 mg/g for caffeine and 3.75 mg/g for chlorogenic acid. Vietnamese coffee showed that the average concentrations were 17.79 mg/g for caffeine and 1.12 mg/g for chlorogenic acid. This study can contribute to a better understanding of the contents of caffeine and chlorogenic acid in various coffee beans in order to evaluate dietary intake.

Keywords

References

  1. Andersen LF, Jacobs DR, Carlsen MH, Blomhoff R(2006) Consumption of coffee is associated with reduced risk of death attributed to inflammatory and cardiovascular diseases in the Iowa women's health study. Am J Clin Nutr 83(5), 1039-1046
  2. Brown CA, Bolton-Smith C, Woodward M, Tunstall- Pedoe H(1993) Coffee and tea consumption and the prevalence of coronary heart disease in men and women: results from the Scottish heart health study. J Epidemiol Community Health 47(3), 171-175 https://doi.org/10.1136/jech.47.3.171
  3. Chu YF, Brown PH, Barbara J, Chen Y, Black RM, Williams CE, Lin Y-C, Hsu CW, Cheng IH(2009) Roasted coffees high in lipophilic antioxidants and chlorogenic acid lactones are more neuroprotective than green coffees. J Agric Food Chem 57(20), 9801-9808 https://doi.org/10.1021/jf902095z
  4. Farah A, Monteiro M, Donangelo CM, Lafay S(2008) Chlorogenic acids from green coffee extract are highly bioavailable in humans. J Nutr 138(12), 2309-2315 https://doi.org/10.3945/jn.108.095554
  5. Fujioka K, Shibamoto T(2008) Chlorogenic acid and caffeine contents in various commercial brewed coffees. Food Chem 106(1), 217-221 https://doi.org/10.1016/j.foodchem.2007.05.091
  6. Heckman MA, Weil J, Mejia EG(2010) Caffeine (1,3,7-trimethylxanthine) in foods: A comprehensive review on consumption, functionality, safety, and regulatory matters. J Food Sci 75(3), 77-87 https://doi.org/10.1111/j.1750-3841.2010.01561.x
  7. Huxley R, Lee CM, Barzi F, Timmermeister L, Czernichow S, Perkovic V, Grobbee DE, Batty D, Woodward M(2009) Coffee, decaffeinated coffee, and tea consumption in relation to incident type 2 diabetes mellitus: a systematic review with meta-analysis. Arch Intern Med 169 (22), 2053-2063 https://doi.org/10.1001/archinternmed.2009.439
  8. Johnson-Kozlow M, Kritz-Silverstein D, Barrett- Connor E, Morton D, Marilyn J-K, Donna K-S, Elizabeth B-C, Deborah M(2002) Coffee consumption and cognitive function among older adults. Am J Epidemiol 156(9), 842-850 https://doi.org/10.1093/aje/kwf119
  9. Kang NJ, Lee KW, Kim BH, Bode AM, Lee H-J, Heo Y-S, Boardman L, Limburg P, Lee HJ, Dong(2011) Coffee phenolic phytochemicals suppress colon cancer metastasis by targeting MEK and TOPK. Carcinog 32(6), 921-928 https://doi.org/10.1093/carcin/bgr022
  10. Klatsky AL, Morton C, Udaltsova N, Friedman GD(2006) Coffee, cirrhosis, and transaminase enzymes. Arch Intern Med 166(11), 1190-1195 https://doi.org/10.1001/archinte.166.11.1190
  11. Lopez GE, Dam RM, Willett WC(2006) Coffee consumption and coronary heart disease in men and women: A prospective cohort study. Circ 113(17), 2045-2053 https://doi.org/10.1161/CIRCULATIONAHA.105.598664
  12. Lindsay J, Laurin D, Verreault R, Hébert R, Helliwell B, Hill GB, McDowell I(2002) Risk factors for alzheimer's disease: A prospective analysis from the Canadian study of health and aging. Am J Epidemiol 156(5), 445-453 https://doi.org/10.1093/aje/kwf074
  13. Maia L, de Mendonça A(2002) Does caffeine intake protect from alzheimer's disease. Eur J Neurol 9(4), 377-382 https://doi.org/10.1046/j.1468-1331.2002.00421.x
  14. Marllyn J-K, Donna K-S, Ellzabeth B-C, Deborah M(2002) Coffee consumption and cognitive function among older adults. Am J Epidemiol 156(9), 842-850 https://doi.org/10.1093/aje/kwf119
  15. Matsuura H, Mure K, Nishio N, Kitano N, Nagai N, Takeshita T(2012) Relationship between coffee consumption and prevalence of metabolic syndrome among Japanese civil servants. J Epidemiol 22(2), 160-166 https://doi.org/10.2188/jea.JE20110068
  16. Michael FL, Meir JS, Walter CW, Donna S, Graham AC, Edward LG(2002) Coffee intake is associated with lower risk of symptomatic gallstone disease in women. Gastroenterol 123(6), 1823-1830 https://doi.org/10.1053/gast.2002.37054
  17. Michael FL, Walter CW, Eric BR, Meir JS, Donna S, Graham AC, Edward LG(1999) A prospective study of coffee consumption and the risk of symptomatic gallstone disease in men. J Am Med Assoc 281, 2106-2112 https://doi.org/10.1001/jama.281.22.2106
  18. Munoz LM, Lönnerdal B, Keen CL, Dewey KG(1988) Coffee consumption as a factor in iron deficiency anemia among pregnant women and their infants in Costa Rica. Am J Clin Nutr 48(3), 645-651
  19. O HJ(2009) Import trade trends of coffee for five years recently. Korea Customs Service Report, pp1-5
  20. Phan TTD, Kuban V, Kráčmar S(2012) Determination of caffeine contents of coffee brands in the vietnamese market. J Microbiology Biotechnol Food Sci 1, 995-1002
  21. Ricketts ML, Boekschoten MV, Kreeft AJ, Hooiveld GJ, Moen CJ, Müller M, Frants RR, Kasanmoentalib S, Post SM, Princen HM, Porter JG, Katan MB, Hofker MH, Moore DD(2007) The cholesterol-raising factor from coffee beans, cafestol, as an agonist ligand for the farnesoid and pregnane X receptors. Mol Endocrinol 21(7), 1603-1616 https://doi.org/10.1210/me.2007-0133
  22. Ross GW, Abbott RD, Petrovitch H, Morens DM, Grandinetti A, Tung KH, Tanner CM, Masaki KH, Blanchette PL, Curb JD, Popper JS, White LR(2000) Association of coffee and caffeine intake with the risk of parkinson disease. J Am Med Assoc 283(20), 2674-2679 https://doi.org/10.1001/jama.283.20.2674
  23. Song YJ, Kristal AR, Wicklund KG, Cushing-Haugen KL, Rossing MA(2008) Coffee, tea, colas, and risk of epithelial ovarian cancer. Cancer Epidemiol Biomark Prev 17(3), 712-716 https://doi.org/10.1158/1055-9965.EPI-07-2511
  24. Ton TG, Watson NF, Longstreth WT(2010) Associations between narcolepsy and consumption of alcohol and caffeinated beverages among genetically susceptible individuals: A population-based case-control study. J Clin Sleep Med 6(4), 406
  25. Wanyika HN, Gatebe EG, Gitu LM, Ngumba EK, Maritim CW(2010) Determination of caffeine content of tea and instant coffee brands found in the Kenyan market. Afr J Food Sci 4(6), 353-358
  26. Wisborg K, Kesmodel U, Bech BH, Hedegaard M, Henriksen TB(2003) Maternal consumption of coffee during pregnancy and stillbirth and infant death in first year of life: Prospective study. BMJ 326(7386), 420-424 https://doi.org/10.1136/bmj.326.7386.420
  27. Zampelas A, Panagiotakos DB, Pitsavos C, Chrysohoou C, Stefanadis C(2004) Associations between coffee consumption and inflammatory markers in healthy persons. Am J Clin Nutr 80(4), 862-867
  28. Zhang QL, Lian HZ, Wang WH, Chen HY(2005) Separation of caffeine and theophyllin in poly (dimethylsiloxane) micro channel electrophoresis with electrochemical detection. J Chromatogr A 1098, 172-176 https://doi.org/10.1016/j.chroma.2005.08.055

Cited by

  1. 미선나무의 저온 추출 공정에 의한 항주름 활성 증진 vol.23, pp.3, 2013, https://doi.org/10.7783/kjmcs.2015.23.3.231