Korean Journal of Radiology

The Korean Society of Radiology (대한영상의학회)
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Placental Transmogrification of the Lung

  • Kim, Jin Woo (Department of Radiology, Yonsei University Wonju College of Medicine) ;
  • Park, Il Hwan (Department of Thoracic and Cardiovascular Surgery, Yonsei University Wonju College of Medicine) ;
  • Kwon, Woocheol (Department of Radiology, Yonsei University Wonju College of Medicine) ;
  • Eom, Min Seob (Department of Pathology, Yonsei University Wonju College of Medicine) ;
  • Kim, Young Ju (Department of Radiology, Yonsei University Wonju College of Medicine) ;
  • Oh, Joong Hwan (Department of Thoracic and Cardiovascular Surgery, Yonsei University Wonju College of Medicine)
  • Received : 2012.11.30
  • Accepted : 2013.08.04
  • Published : 2013.11.01
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Abstract

Placental transmogrification is a very rare lung disease, where the alveoli resemble the chorionic villi of placenta, and this change is a characteristic finding. A 31-year-old female patient presented with cough and dyspnea that had begun 2 weeks prior to admission. Along with giant bulla found in the left upper lung field, subsegmental consolidation was also identified in the lingular segment on plain chest radiograph and CT scan. Wedge resection was performed to remove the bulla. Pathologic examination of the resected bulla revealed destruction of the normal structures and characteristic villous and papillary changes. These changes led to a diagnosis of placental transmogrification. We made an encounter of an unusual placental transmogrification which had different image findings from other reported transmogrification cases. Thus, we report an atypical placental transmogrification case where both consolidation and giant bulla coexist.

Keywords

References

  1. McChesney T. Placental transmogrification of the lung: a unique case with remarkable histopathologic features. Lab Invest 1979;40:245-246
  2. Horsley WS, Gal AA, Mansour KA. Unilateral giant bullous emphysema with placental transmogrification of the lung. Ann Thorac Surg 1997;64:226-228 https://doi.org/10.1016/S0003-4975(97)00274-9
  3. Ferretti GR, Kocier M, Moro-Sibilot D, Brichon PY, Lantuejoul S. Placental transmogrification of the lung: CT-pathologic correlation of a rare pulmonary nodule. AJR Am J Roentgenol 2004;183:99-101 https://doi.org/10.2214/ajr.183.1.1830099
  4. Fidler ME, Koomen M, Sebek B, Greco MA, Rizk CC, Askin FB. Placental transmogrification of the lung, a histologic variant of giant bullous emphysema. Clinicopathological study of three further cases. Am J Surg Pathol 1995;19:563-570 https://doi.org/10.1097/00000478-199505000-00008
  5. Theile A, Wex P, Muller KM. [Placentoid malformation of the lung as differential diagnosis of localized emphysema]. Pneumologie 1997;51:550-554
  6. Park ES, Han J, Koh WJ, Lee KS, Kim J, Seo J, et al. Placental transmogrification of the lung: a brief case report. Korean J Pathol 2008;42:308-310
  7. Xu R, Murray M, Jagirdar J, Delgado Y, Melamed J. Placental transmogrification of the lung is a histologic pattern frequently associated with pulmonary fibrochondromatous hamartoma. Arch Pathol Lab Med 2002;126:562-566
  8. Cavazza A, Lantuejoul S, Sartori G, Bigiani N, Maiorana A, Pasquinelli G, et al. Placental transmogrification of the lung: clinicopathologic, immunohistochemical and molecular study of two cases, with particular emphasis on the interstitial clear cells. Hum Pathol 2004;35:517-521 https://doi.org/10.1016/j.humpath.2003.10.023
  9. Shapiro M, Vidal C, Lipskar AM, Gil J, Litle VR. Placental transmogrification of the lung presenting as emphysema and a lung mass. Ann Thorac Surg 2009;87:615-616 https://doi.org/10.1016/j.athoracsur.2008.05.076

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