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Irreversible Electroporation of a Hepatocellular Carcinoma Lesion Adjacent to a Transjugular Intrahepatic Portosystemic Shunt Stent Graft

  • Niessen, Christoph (Department of Radiology, University Medical Center Regensburg) ;
  • Jung, Ernst Michael (Department of Radiology, University Medical Center Regensburg) ;
  • Wohlgemuth, Walter A. (Department of Radiology, University Medical Center Regensburg) ;
  • Trabold, Benedikt (Department of Anaesthesia, University Medical Center Regensburg) ;
  • Haimerl, Michael (Department of Radiology, University Medical Center Regensburg) ;
  • Schreyer, Andreas (Department of Radiology, University Medical Center Regensburg) ;
  • Stroszczynski, Christian (Department of Radiology, University Medical Center Regensburg) ;
  • Wiggermann, Philipp (Department of Radiology, University Medical Center Regensburg)
  • Received : 2012.07.12
  • Accepted : 2013.02.22
  • Published : 2013.09.01

Abstract

We report in a 65-year-old man hepatocellular carcinoma adjacent to a transjugular intrahepatic portosystemic shunt stent-graft which was successfully treated with irreversible electroporation (IRE). IRE is a new non-thermal tissue ablation technique which uses electrical pulses to induce cell necrosis by irreversible membrane poration. IRE proved to be more advantageous in the ablation of perivascular tumor with little injury to the surrounding structures.

Keywords

References

  1. Yun BL, Lee JM, Baek JH, Kim SH, Lee JY, Han JK, et al. Radiofrequency ablation for treating liver metastases from a non-colorectal origin. Korean J Radiol 2011;12:579-587 https://doi.org/10.3348/kjr.2011.12.5.579
  2. Patterson EJ, Scudamore CH, Owen DA, Nagy AG, Buczkowski AK. Radiofrequency ablation of porcine liver in vivo: effects of blood flow and treatment time on lesion size. Ann Surg 1998;227:559-565 https://doi.org/10.1097/00000658-199804000-00018
  3. Dupuy DE, Aswad B, Ng T. Irreversible electroporation in a Swine lung model. Cardiovasc Intervent Radiol 2011;34:391-395 https://doi.org/10.1007/s00270-010-0091-9
  4. Lee EW, Loh CT, Kee ST. Imaging guided percutaneous irreversible electroporation: ultrasound and immunohistological correlation. Technol Cancer Res Treat 2007;6:287-294 https://doi.org/10.1177/153303460700600404
  5. Deodhar A, Dickfeld T, Single GW, Hamilton WC Jr, Thornton RH, Sofocleous CT, et al. Irreversible electroporation near the heart: ventricular arrhythmias can be prevented with ECG synchronization. AJR Am J Roentgenol 2011;196:W330-W335 https://doi.org/10.2214/AJR.10.4490
  6. Kingham TP, Karkar AM, D'Angelica MI, Allen PJ, Dematteo RP, Getrajdman GI, et al. Ablation of perivascular hepatic malignant tumors with irreversible electroporation. J Am Coll Surg 2012;215:379-387 https://doi.org/10.1016/j.jamcollsurg.2012.04.029
  7. Bruix J, Sherman M; Practice Guidelines Committee, American Association for the Study of Liver Diseases. Management of hepatocellular carcinoma. Hepatology 2005;42:1208-1236 https://doi.org/10.1002/hep.20933
  8. Cho YK, Kim JK, Kim MY, Rhim H, Han JK. Systematic review of randomized trials for hepatocellular carcinoma treated with percutaneous ablation therapies. Hepatology 2009;49:453-459 https://doi.org/10.1002/hep.22648
  9. Kamusella P, Wiggermann P, Wissgott C, Andresen R, Stroszczynski C. [Thermal protection of targeted air instillation in CT-guided radiofrequency ablation]. Rofo 2011;183:952-955 https://doi.org/10.1055/s-0031-1273447
  10. Raman SS, Lu DS, Vodopich DJ, Sayre J, Lassman C. Minimizing diaphragmatic injury during radio-frequency ablation: efficacy of subphrenic peritoneal saline injection in a porcine model. Radiology 2002;222:819-823 https://doi.org/10.1148/radiol.2223001805
  11. Lencioni R, Crocetti L. Local-regional treatment of hepatocellular carcinoma. Radiology 2012;262:43-58 https://doi.org/10.1148/radiol.11110144
  12. Chang NK, Shin SS, Kim JW, Kim HJ, Jeong YY, Heo SH, et al. Effect of ultrasound-guided radiofrequency ablation in incompletely treated hepatocellular carcinoma after transcatheter arterial chemoembolization. Korean J Radiol 2012;13 Suppl 1:S104-S111 https://doi.org/10.3348/kjr.2012.13.S1.S104
  13. Lee J, Lee JM, Yoon JH, Lee JY, Kim SH, Lee JE, et al. Percutaneous radiofrequency ablation with multiple electrodes for medium-sized hepatocellular carcinomas. Korean J Radiol 2012;13:34-43 https://doi.org/10.3348/kjr.2012.13.1.34

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  2. Bursts of Bipolar Microsecond Pulses Inhibit Tumor Growth vol.5, pp.None, 2015, https://doi.org/10.1038/srep14999
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