The Korean Journal of Medicine

The Korean Association of Internal Medicine (대한내과학회)
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Two Cases of Refractory Pseudomembranous Colitis that Healed Following Fecal Microbiota Transplantation

대변 세균총 이식으로 치료된 난치성 위막성 대장염 2예

  • Gweon, Tae Geun (Department of Internal Medicine, The Catholic University of Korea College of Medicine) ;
  • Choi, Myung Gyu (Department of Internal Medicine, The Catholic University of Korea College of Medicine) ;
  • Lee, Soon Kyu (Department of Internal Medicine, The Catholic University of Korea College of Medicine) ;
  • Ha, Jeong Hoon (Department of Internal Medicine, The Catholic University of Korea College of Medicine) ;
  • Kim, Eun Young (Department of Internal Medicine, The Catholic University of Korea College of Medicine) ;
  • Go, Byoung Soung (Department of Internal Medicine, The Catholic University of Korea College of Medicine) ;
  • Kim, Sang Woo (Department of Internal Medicine, The Catholic University of Korea College of Medicine)
  • 권태근 (가톨릭대학교 의과대학 내과학교실) ;
  • 최명규 (가톨릭대학교 의과대학 내과학교실) ;
  • 이순규 (가톨릭대학교 의과대학 내과학교실) ;
  • 하정훈 (가톨릭대학교 의과대학 내과학교실) ;
  • 김은영 (가톨릭대학교 의과대학 내과학교실) ;
  • 고병성 (가톨릭대학교 의과대학 내과학교실) ;
  • 김상우 (가톨릭대학교 의과대학 내과학교실)
  • Received : 2012.06.27
  • Accepted : 2012.09.28
  • Published : 2013.03.01
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Abstract

The incidence, recurrence, and mortality of Clostridium difficile infection are increasing and the standard therapy is oral metronidazole or vancomycin. Since treatment failure with standard therapy is increasing, an alternative therapy is needed. Fecal microbiota transplantation is one effective method in patients with refractory or recurrent C. difficile infection, including pseudomembranous colitis. Here, we report two cases of refractory pseudomembranous colitis treated with fecal microbiota transplantation.

항생제에 반응하지 않는 난치성, 재발성의 위막성 대장염 환자 2명에 대해 대변 세균총 이식을 통해 치료하였기에 문헌고찰과 함께 보고하는 바이다.

Keywords

References

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