The Korean Journal of Medicine

The Korean Association of Internal Medicine (대한내과학회)
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A Case of Lung Disease and Vertebral Osteomyelitis Due to Nontuberculous Mycobacteria in a Kidney Transplant Recipient

신이식 환자의 Nontuberculous mycobacteria 폐질환과 척추염 1예

  • Shin, Junam (Division of Nephrology, Department of Internal Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Kim, Soo Min (Division of Nephrology, Department of Internal Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Kim, Dae Joong (Division of Nephrology, Department of Internal Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Kim, Yoon-Goo (Division of Nephrology, Department of Internal Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Oh, Ha Young (Division of Nephrology, Department of Internal Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Jeon, Kyeongman (Division of Pulmonology, Department of Internal Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Huh, Wooseong (Division of Nephrology, Department of Internal Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine)
  • 신준암 (성균관대학교 의과대학 삼성서울병원 신장내과) ;
  • 김수민 (성균관대학교 의과대학 삼성서울병원 신장내과) ;
  • 김대중 (성균관대학교 의과대학 삼성서울병원 신장내과) ;
  • 김윤구 (성균관대학교 의과대학 삼성서울병원 신장내과) ;
  • 오하영 (성균관대학교 의과대학 삼성서울병원 신장내과) ;
  • 전경만 (성균관대학교 의과대학 삼성서울병원 호흡기내과) ;
  • 허우성 (성균관대학교 의과대학 삼성서울병원 신장내과)
  • Received : 2012.05.27
  • Accepted : 2012.07.31
  • Published : 2013.02.01
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Abstract

Nontuberculous mycobacteria (NTM) infections in kidney transplant recipients (KTR) are rare. We describe here a 52-year-old female with vertebral osteomyelitis caused by NTM, who received a kidney transplant 5 years earlier. She had been diagnosed with NTM lung disease 1 year prior. NTM therapy was delayed due to esophageal candidiasis. Mycobacterium intracellulare was isolated from sputum and bone tissue. The pattern of drug-susceptibility testing in both specimens was identical. NTM vertebral osteomyelitis due to direct inoculation is rare, and was in this case a disseminated NTM disease. The subjective symptoms resolved after 4 months of NTM treatment. This suggests that early NTM treatment is important for KTRs who have NTM disease during immunosuppressive therapy.

신이식을 받은 환자에서 NTM 폐질환이나 척추염에 대한 증례 보고가 국내에서는 아직 없었다. 저자들은 신이식을 받고 면역억제제를 복용하고 있는 환자에서 M. intracellulare에 의한 폐질환과 척추염을 진단하여 병합 항균 요법으로 뚜렷한 임상적 호전을 보인 1예를 경험하였기에 보고하는 바이다.

Keywords

References

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