The Korean Journal of Medicine

The Korean Association of Internal Medicine (대한내과학회)
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A Case of Dyspnea Caused by Local Botulinum Toxin Type A Injection

국소적 보툴리늄 독소 A 주사에 의한 호흡곤란 1예

  • So, Hoon Sub (Department of Pulmonology and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Moon, Min Young (Department of Pulmonology and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Lee, Jung Su (Department of Pulmonology and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Kim, Ho Cheol (Department of Pulmonology and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Kang, Byung Chul (Department of Otolaryngology, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Koh, Younsuck (Department of Pulmonology and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine)
  • 소훈섭 (울산대학교 의과대학 서울아산병원 호흡기내과) ;
  • 문민영 (울산대학교 의과대학 서울아산병원 호흡기내과) ;
  • 이정수 (울산대학교 의과대학 서울아산병원 호흡기내과) ;
  • 김호철 (울산대학교 의과대학 서울아산병원 호흡기내과) ;
  • 강병철 (울산대학교 의과대학 서울아산병원 이비인후과) ;
  • 고윤석 (울산대학교 의과대학 서울아산병원 호흡기내과)
  • Received : 2012.10.30
  • Accepted : 2012.12.27
  • Published : 2013.06.01
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Abstract

Botulinum toxin type A is widely used for functional improvement of muscles and aesthetic plastic surgery. It paralyzes the injected muscle by inhibiting acetylcholine release from synapses of neuromuscular junctions. We herein report a case of progressive respiratory distress after botulinum toxin injection at both the gastrocnemius and soleus muscles. The patient also showed ptosis, dysphonia, dysphagia, and general weakness. Vocal cord dysfunction was observed by laryngoscopy. Other neurologic examination findings, including those of the physical examination, brain MRI, and Jolly's test, were normal. To our knowledge, this is the first report of botulinum toxin injection associated with dyspnea (MRC dyspnea scale, grade 3) in Korea.

국소적으로 투여된 보톡스가 호흡곤란을 일으킨 증례는 국내에 지금까지 보고된 바가 없어 1예를 경험하여 이를 보고하는 바이다.

Keywords

References

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