DOI QR코드

DOI QR Code

A Cerebral Air Embolism after CT-Guided Percutaneous Transthoracic Fine-Needle Aspiration Biopsy of the Lung

CT 유도하 경피적 흉부 세침흡인생검 후 발생한 뇌 공기색전증 1예

  • Cho, Eun Na (Division of Pulmonology, Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine) ;
  • Park, Heejin (Division of Pulmonology, Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine) ;
  • Kim, Hae Won (Division of Pulmonology, Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine) ;
  • Chang, Yoon Soo (Division of Pulmonology, Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine) ;
  • Kim, Hyung Jung (Division of Pulmonology, Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine) ;
  • Ahn, Chul Min (Division of Pulmonology, Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine) ;
  • Byun, Min Kwang (Division of Pulmonology, Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine)
  • 조은나 (연세대학교 의과대학 내과학교실, 강남세브란스병원 호흡기내과) ;
  • 박희진 (연세대학교 의과대학 내과학교실, 강남세브란스병원 호흡기내과) ;
  • 김혜원 (연세대학교 의과대학 내과학교실, 강남세브란스병원 호흡기내과) ;
  • 장윤수 (연세대학교 의과대학 내과학교실, 강남세브란스병원 호흡기내과) ;
  • 김형중 (연세대학교 의과대학 내과학교실, 강남세브란스병원 호흡기내과) ;
  • 안철민 (연세대학교 의과대학 내과학교실, 강남세브란스병원 호흡기내과) ;
  • 변민광 (연세대학교 의과대학 내과학교실, 강남세브란스병원 호흡기내과)
  • Received : 2013.02.08
  • Accepted : 2013.04.11
  • Published : 2013.10.01

Abstract

Low-dose thoracic computed tomography (CT) for the early diagnosis of lung cancer detects many solitary pulmonary nodules. Fine needle aspiration biopsy (FNAB) is the diagnostic method used most commonly in the diagnosis of solitary pulmonary nodules. Cerebral air embolism is a rare, fatal complication of FNAB. Hyperbaric oxygenation therapy within 6 hours of the event ensures a good prognosis with cerebral air embolisms. We present a case of cerebral air embolism that occurred during CT-guided lung FNAB biopsy that was treated with hyperbaric oxygenation within 6 hours. The patient recovered completely from the neurological deficit and had a favorable long-term outcome.

고립성 폐결절의 진단을 위해 경피적 흉부 세침흡인생검을 하는 경우 기흉이나 혈흉, 공기색전증 등의 합병증 발생빈도가 유의하게 증가하는 환자군을 확인하여 시술을 진행하는 동안 활력징후 및 임상양상을 주의 깊게 관찰하여야 하며 공기색전증의 임상양상을 보일 경우 즉각적인 진단과 6시간 내의 빠른 고압산소치료를 시행하여야 한다. 이전의 증례보고와 비교하였을 때 본 증례는 세침흡인생검 시행 시 합병증의 발생위험도 예측에 따른 환자 관찰과 임상증상에 중점을 둔 진단 및 빠른 고압산소치료가 좋은 치료 결과를 내는 방법임을 보여주고 있다.

Keywords

References

  1. Ohno Y, Hatabu H, Takenaka D, et al. CT-guided transthoracic needle aspiration biopsy of small (< or = 20 mm) solitary pulmonary nodules. AJR Am J Roentgenol 2003; 180:1665-1669. https://doi.org/10.2214/ajr.180.6.1801665
  2. Tomiyama N, Yasuhara Y, Nakajima Y, et al. CT-guided needle biopsy of lung lesions: a survey of severe complication based on 9783 biopsies in Japan. Eur J Radiol 2006; 59:60-64. https://doi.org/10.1016/j.ejrad.2006.02.001
  3. Yang DK, Lee SK, Suh SW, et al. A case of cerebral air embolism occurred after CT-guided transthoracic needle biopsy. Tuberc Respir Dis 2004;57:480-483. https://doi.org/10.4046/trd.2004.57.5.480
  4. Wu CC, Maher MM, Shepard JA. Complications of CT-guided percutaneous needle biopsy of the chest: prevention and management. AJR Am J Roentgenol 2011;196:W678-682. https://doi.org/10.2214/AJR.10.4659
  5. Trytko BE, Bennett MH. Arterial gas embolism: a review of cases at Prince of Wales Hospital, Sydney, 1996 to 2006. Anaesth Intensive Care 2008;36:60-64.
  6. Hodgson M, Beran RG, Shirtley G. The role of computed tomography in the assessment of neurologic sequelae of decompression sickness. Arch Neurol 1988;45:1033-1035. https://doi.org/10.1001/archneur.1988.00520330125021
  7. Guimaraes MD, Andrade MQ, Fonte AC, Benevides G, Chojniak R, Gross JL. Predictive complication factors for CT-guided fine needle aspiration biopsy of pulmonary lesions. Clinics (Sao Paulo) 2010;65:847-850. https://doi.org/10.1590/S1807-59322010000900006
  8. Yankelevitz DF, Henschke CI, Koizumi JH, Altorki NK, Libby D. CT-guided transthoracic needle biopsy of small solitary pulmonary nodules. Clin Imaging 1997;21:107-110. https://doi.org/10.1016/S0899-7071(96)00011-3
  9. Blanc P, Boussuges A, Henriette K, Sainty JM, Deleflie M. Iatrogenic cerebral air embolism: importance of an early hyperbaric oxygenation. Intensive Care Med 2002;28:559-563. https://doi.org/10.1007/s00134-002-1255-0
  10. Um SJ, Lee SK, Yang DK, et al. Four cases of a cerebral air embolism complicating a percutaneous transthoracic needle biopsy. Korean J Radiol 2009;10:81-84. https://doi.org/10.3348/kjr.2009.10.1.81