Korean Journal of Veterinary Service (한국동물위생학회지)

The Korean Society of Veterinary Service (한국동물위생학회)
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Development of antibodies after foot and mouth disease vaccination in pigs

돼지에서 구제역 백신 접종 후 항체가 변화 조사

  • Ahn, Gil-Ho (Gyeonggi Province Northern Livestock and Veterinary Service) ;
  • Bae, Jin-Gyu (Gyeonggi Province Veterinary Service Center) ;
  • Jung, Kwang (Gyeonggi Province Northern Livestock and Veterinary Service) ;
  • Wang, Young-Il (Korea Pork Producer Association) ;
  • Jung, Jun-Yong (Gyeonggi Province Northern Livestock and Veterinary Service) ;
  • Kang, Soon-Keun (Gyeonggi Province Northern Livestock and Veterinary Service) ;
  • Kwon, Hyuk-Moo (College of Veterinary Medicine, Kangwon National University)
  • 안길호 (경기도북부축산위생연구소) ;
  • 배진규 (경기도축산위생연구소) ;
  • 정광 (경기도북부축산위생연구소) ;
  • 왕영일 (대한한돈협회) ;
  • 정준용 (경기도북부축산위생연구소) ;
  • 강순근 (경기도북부축산위생연구소) ;
  • 권혁무 (강원대학교 수의과대학)
  • Received : 2013.01.09
  • Accepted : 2013.03.25
  • Published : 2013.03.30
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Abstract

Three serotypes (O+A+Asia1 type) of the foot-and-mouth disease (FMD) vaccine were injected into cloven-hoofed animals in Korea after the nationwide spread of FMD at the end of 2010. This study was conducted to investigate FMD antibody development after FMD vaccination, and to determine whether there was a significant correlation between the antibody titer of the sow and the antibody titer of the growing pigs. The antibody titer (percentage inhibition [PI] titer) of the sow (gilt) after FMD vaccination was maintained at a level higher than 50 (P<0.05) for 5 months. A higher PI titer for the 1-month-old growing pigs corresponded with greater inhibition of the PI titer of the vaccinated growing pigs (P<0.05). A negative correlation (P<0.05) between the PI titer of the 1-month-old growing pigs and the PI titer of 3-month-old growing pigs, 4-month-old growing pigs after FMD vaccination at 2 months, 3months was identified, with a coefficient of determination ($R^2$) of 0.274. Thus the PI titer of the growing pigs was inhibited to a greater degree when vaccination was performed at 2 months of age than at 3 months. However, many other factors likely influence growing pigs' PI titer in addition to the PI titer of the sow and age at vaccination, given that the coefficient of determination was somewhat lower.

Keywords

References

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