A Case of Uterine Adenocarcinoma in A Spayed Female Dog

중성화된 암캐에서 발생한 자궁 선암종 증례

  • Choi, Ul Soo (Department of Veterinary Clinical Pathology and Bio-Safety Research Institute, College of Veterinary Medicine, Chonbuk National University)
  • 최을수 (전북대학교 수의과대학 수의임상병리학과, 생체안전성 연구소)
  • Accepted : 2013.02.14
  • Published : 2013.02.28

Abstract

A 10-year-old spayed female Pekinese dog was referred to veterinary medical teaching hospital of Chonbuk National University with signs of dysuria, abdominal distension, and hematuria. Abdominal radiography revealed a large oval soft tissue mass in cranial abdomen, which was a fluid filled cyst containing a round mass by ultrasonography. Exploratory laparatomy found a 4 cm cyst containing reddish brown fluid and a 1.5 cm small round mass attached to the wall. Cytological impression of the imprint smears of the resected mass were highly malignant adenocarcinoma, which was confirmed by histopathology of the mass and the cyst. After the surgery the patient recovered uneventfully and discharged. The tumor recurred about one year after surgery, and second surgery performed at the owner's request. However the tumor recurred in two months with metastatic disease in the lung and the dog survived three more months after surgery.

10세령 중성화된 페키니즈 견이 배뇨장애와 복부 팽대와 혈뇨 증상으로 내원하였다. 복부 방사선 촬영에서 상복부의 난원형 연조직 종괴가 발견되었으며 초음파 검사에서 액이 차 있고 종괴가 있는 낭으로 확인되었다. 탐색적 개복술을 통해 직경 4 cm 크기의 낭성 구조를 발견하였으며 적갈색의 액성 물질과 벽에 붙어 있는 직경 1.5 cm 크기의 원형 종괴를 확인하고 수술적으로 제거하였다. 절개한 종괴의 날인 도말 표본에 대한 세포학적 검사 결과 여러가지 악성 조건을 만족하는 선암종 세포가 다수 관찰되었으며, 조직병리 검사에서 확진되었다. 환자는 수술 회복되어 퇴원하였으며 재발증상의 징후 없이 지내다가 술 후1년 후 증상이 재발되어 내원하였고 종괴가 재발되었음을 확인하고 종괴 제거를 위한 2차 수술을 실시하였다. 환자는 퇴원 후 2개월째에 다시 내원하였으며 종괴가 재발되고 폐 전이가 발생한 것을 확인할 수 있었다. 환자는 이후 3개월을 더 생존하다가 폐사하였다.

Keywords

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