Annals of Clinical Neurophysiology

The Korean Society of Clinical Neurophysiology (대한임상신경생리학회)
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Cerebellar Control of Saccades

소뇌의 단속안구운동 조절

  • Choi, Jae-Hwan (Department of Neurology, Pusan National University Yangsan Hospital) ;
  • Choi, Kwang-Dong (Department of Neurology, Pusan National University College of Medicine)
  • 최재환 (양산부산대학교병원 신경과) ;
  • 최광동 (부산대학교 의과대학 신경과학교실)
  • Received : 2013.12.10
  • Accepted : 2013.12.17
  • Published : 2013.12.30
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Abstract

Saccades are rapid eye movements that shift the line of sight between successive points of fixation. The cerebellum calibrates saccadic amplitude (dorsal vermis and fastigial nucleus) and the saccadic pulse-step match (flocculus) for optimal visuo-ocular motor behavior. Based on electrophysiology and the pharmacological inactivation studies, early activity in one fastigial nucleus could be important for accelerating the eyes at the beginning of a saccade, and the later activity in the other fastigial nucleus could be critical for stopping the eye on target, which is controlled by inhibitory projection from the dorsal vermis. The cerebellum could monitor a corollary discharge of the saccadic command and terminate the eye movement when it is calculated to be on target. The fastigial nucleus and dorsal vermis also participate in the adaptive control of saccadic accuracy.

Keywords

References

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