References
- Andersen, J.R. and T. Lubberstedt. 2003. Functional markers in plants. Trends Plant Sci. 11:554-560.
- Appleby, N., D. Edwards, and J. Batley. 2009. New technologies for ultra-high throughput genotyping in plants. Methods Mol. Biol. 513:19-39. https://doi.org/10.1007/978-1-59745-427-8_2
- Chen, X. and P.F. Sullivan. 2003. Single nucleotide polymorphism genotyping: Biochemistry, protocol, cost and throughput. Pharmacogenomics J. 3:77-96. https://doi.org/10.1038/sj.tpj.6500167
- Clarke, A.E. and H.A. Jones, and T.M. Little. 1944. Inheritance of bulb color in the onion. Genetics 29:569-575.
- Clere, N., S. Faure, M.C. Martinez, and R. Andriantsitohaina. 2011. Anticancer properties of flavonoids: Roles in various stages of carcinogenesis. Cardiovasc. Hematol. Agents Med. Chem. 9:62-77. https://doi.org/10.2174/187152511796196498
- Cook, N.C. and S. Samman. 1996. Flavonoids-chemistry, metabolism, cardioprotective effects, and dietary sources. Nutr. Biochem. 7:66-76. https://doi.org/10.1016/0955-2863(95)00168-9
- Cushnie, T.P. and A.J. Lamb. 2011. Recent advances in understanding the antibacterial properties of flavonoids. Int. J. Antimicrob. Agents 38:99-107. https://doi.org/10.1016/j.ijantimicag.2011.02.014
- Dao, T.T.H., H.H.M. Linthorst, and R. Verpoorte. 2011. Chalcone synthase and tis functions in plant resistance. Phytochem. Rev. 10:397-412. https://doi.org/10.1007/s11101-011-9211-7
- Doyle, J.J. and J.L. Doyle. 1987. A rapid DNA isolation procedure for small quantities of fresh leaf tissue. Phytochem. Bull. 19:11-15.
- Edwards, D. and J. Batley. 2010. Plant genome sequencing: applications for crop improvement. Plant Biotechnol. J. 8:2-9. https://doi.org/10.1111/j.1467-7652.2009.00459.x
- El-Shafie, M.W. and G.N. Davis. 1967. Inheritance of bulb color in the onion (Allium cepa L.). Hilgardia 38:607-622. https://doi.org/10.3733/hilg.v38n17p607
- Ferrer, J.L., M.B. Austin, C. Stewart, Jr., and J.P. Noel. 2008. Structure and function of enzymes involved in the biosynthesis of phenylpropanoids. Plant Physiol. Biochem. 46:356-370. https://doi.org/10.1016/j.plaphy.2007.12.009
- Fini, A., C. Brunetti, M. Di Ferdinando, F. Ferrini, and M. Tattini. 2011. Stress-induced flavonoid biosynthesis and the antioxidant machinery of plants. Plant Signal Behav. 6:709-711. https://doi.org/10.4161/psb.6.5.15069
- Fossen, T., O.M. Andersen, D.O. Ovstedal, A.T. Pedersen, and A. Raknes. 1996. Characteristic anthocyanin pattern from onions and other Allium spp. J. Food Sci. 61:703-706. https://doi.org/10.1111/j.1365-2621.1996.tb12185.x
- Goodrich, J., R. Carpenter, and E.S. Coen. 1992. A common gene regulates pigmentation pattern in diverse plant species. Cell 68:955-964. https://doi.org/10.1016/0092-8674(92)90038-E
- Holton, T.A. and E.C. Cornish 1995. Genetics and biochemistry of anthocyanin biosynthesis. Plant Cell 7:1070-1083.
- Kim, S., D. Baek, D.Y. Cho, and M. Yoon. 2009. Identification of two novel inactive DFR-A alleles responsible for failure to produce anthocyanin and development of a simple PCR-based molecular marker for bulb color selection in onion (Allium cepa L.) Theor. Appl. Genet. 118:1391-1399. https://doi.org/10.1007/s00122-009-0989-2
- Kim, S., M. Binzel, K. Yoo, S. Park, and L.M. Pike. 2004a. Inactivation of DFR (dihydroflavonol 4-reductase) gene transcription results in blockage of anthocyanin production in yellow onions (Allium cepa). Mol. Breed. 14:253-263. https://doi.org/10.1023/B:MOLB.0000047770.92977.04
- Kim, S., R. Jones, K. Yoo, and L.M. Pike. 2004b. Gold color in onions (Allium cepa): A natural mutation of the chalcone isomerase gene resulting in a pre-mature termination codon. Mol. Gen. Genomics 272:411-419. https://doi.org/10.1007/s00438-004-1076-7
- Kim, S., R. Jones, K. Yoo, and L.M. Pike. 2005a.. The L locus, one of complementary genes required for anthocyanin production in onions (Allium cepa), encodes anthocyanidin synthase. Theor. Appl. Genet. 111:120-127. https://doi.org/10.1007/s00122-005-2000-1
- Kim, S., K. Yoo, and L.M. Pike. 2005b. The basic color factor, the C locus, encodes a regulatory gene controlling transcription of chalcone synthase genes in onions (Allium cepa). Euphytica 142:273-282. https://doi.org/10.1007/s10681-005-2239-2
- Kim, S., K. Yoo, and L.M. Pike. 2005c. Development of a PCR-based marker utilizing a deletion mutation in the DFR (dihydroflavonol 4-reductase) gene responsible for the lack of anthocyanin production in yellow onions (Allium cepa). Theor. Appl. Genet. 110:588-595. https://doi.org/10.1007/s00122-004-1882-7
- Lotito, S.B. and B. Frei. 2006. Consumption of flavonoids-rich foods and increased plasma antioxidant capacity in humans: cause, consequence, or epiphenomenon? Free Radic. Biol. Med. 41:1727-1746. https://doi.org/10.1016/j.freeradbiomed.2006.04.033
- Nam, E., D.Y. Cho, E. Lee, C. Kim, H. Han, M. Yoon, and S. Kim. 2011. Bulb storability of red and yellow onion (Allium cepa L.) cultivars grown in Korea. Kor. J. Breed. Sci. 43: 132-138.
- Neeraja, C.N., R. Maghirang-Rodriguez, A. Pamplona, S. Heuer, B.C.Y. Collard, E.M. Septiningsih, G. Vergara, D. Sanchez, K. Xu, A.M. Ismail, and D.J. Mackill. 2007. A marker-assisted backcross approach for developing submergence-tolerant rice cultivars. Theor. Appl. Genet. 115:767-776. https://doi.org/10.1007/s00122-007-0607-0
- Neff, M.M., J.D. Neff, J. Chory, and A.E. Pepper. 1998. dCAPS, a simple technique for the genetic analysis of single nucleotide polymorphisms: Experimental applications in Arabidopsis thaliana genetics. Plant J. 14:387-392. https://doi.org/10.1046/j.1365-313X.1998.00124.x
- Neff, M.M., E. Turk, and M. Kalishman. 2002. Web-based primer design for single nucleotide polymorphism analysis. Trends Genet. 18:613-615. https://doi.org/10.1016/S0168-9525(02)02820-2
- Nishiumi, S., S. Miyamoto, K. Kawabata, K. Ohnishi, R. Mukai, A. Murakami, H. Ashida, and J. Terao. 2011. Dietary flavonoids as cancer-preventive and therapeutic biofactors. Front. Biosci. 3:1332-1362.
- Quattrocchio, F., J.F. Wing, H.T.C. Leppen, J.N. Mol, and R.E. Koes. 1993. Regulatory genes controlling anthocyanin pigmentation are functionally conserved among plant species and have distinct sets of target genes. Plant Cell 5:1497-1512. https://doi.org/10.1105/tpc.5.11.1497
- Reiman, G.H. 1931. Genetic factors for pigmentation in the onion and their relation to disease resistance. J. Agr. Res. 42:251-278.
- Rhodes, M.J.C. and K.R. Price. 1996. Analytical problems in the study of flavonoid compounds in onions. Food Chem. 57:113-117. https://doi.org/10.1016/0308-8146(96)00147-1
- Rozen, S. and H.J. Skaletsky. 2000. Primer3 on the WWW for general users and for biologist programmers, p. 365-386. In: S. Krawetz and S. Misener (eds.). Bioinormatics methods and protocols: Methods in molecular biology. Humana Press, Totowa, NJ.
- Russo, M., C. Spagnuolo, I. Tedesco, S. Bilotto, and G.L. Russo. 2012. The flavonoid quercetin in disease prevention and therapy: Facts and fancies. Biochem. Pharmacol. 83:6-15. https://doi.org/10.1016/j.bcp.2011.08.010
- Septiningsih, E.M., A.M. Pamplona, D.L. Sanchez, C.N. Neeraja, G.V. Vergara, S. Heuer, A.M. Ismail, and D.J. Mackill. 2009. Development of submergence-tolerant rice cultivars: The Sub1 locus and beyond. Ann. Bot. 103:151-160.
- Shirley, B.W. 1996. Flavonoid biosynthesis: 'New' functions for an 'old' pathway. Trends Plant Sci. 1:377-382.
- Slimestad, R., T. Fossen, and I.M. Vagen. 2007. Onions: A source of unique dietary flavonoids. J. Agric. Food Chem. 55:10067-10080. https://doi.org/10.1021/jf0712503
- Spelt, C., F. Quattrocchio, J.N. Mol, and R.E. Koes. 2000. Anthocyanin1 of petunia encodes a basic helix-loop-helix protein that directly activates transcription of structural anthocyanin genes. Plant Cell 12:1619-1631. https://doi.org/10.1105/tpc.12.9.1619
- Varshney, R.K., S.N. Nayak, G.D. May, and S.A. Jackson. 2009. Next-generation sequencing technologies and their implications for crop genetics and breeding. Trends Biotechnol. 27:522-530. https://doi.org/10.1016/j.tibtech.2009.05.006
- Veitch, N.C. and R.J. Grayer 2011. Flavonoids and their glycosides, including anthocyanins. Nat. Prod. Rep. 28:1626-1695. https://doi.org/10.1039/c1np00044f
- Vogt, T. 2010. Phenylpropanoid biosynthesis. Mol. Plant 3:2-20. https://doi.org/10.1093/mp/ssp106
- Yamazaki, M., Y. Makita, K. Springob, and K. Saito 2003. Regulatory mechanisms for anthocyanin biosynthesis in chemotypes of Perilla frutescens var. crispa. Biochem. Eng. J. 14:191-197. https://doi.org/10.1016/S1369-703X(02)00222-X
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