Reviewing Research on Laser Therapy of Atopic Dermatitis

아토피 피부염의 레이저 치료에 관한 논문 경향 분석

  • Cho, Jae-Myung (School of Korean Medicine, Pusan National University) ;
  • Hong, Eun-Ju (School of Korean Medicine, Pusan National University) ;
  • Seo, Hyung-Sik (School of Korean Medicine, Pusan National University)
  • 조재명 (부산대학교 한의학전문대학원) ;
  • 홍은주 (부산대학교 한의학전문대학원) ;
  • 서형식 (부산대학교 한의학전문대학원)
  • Received : 2013.01.12
  • Accepted : 2013.02.14
  • Published : 2013.02.25


Objective : The purpose of this study is to analyze research trends on the effects of laser therapy on atopic dermatitis. Methods : We searched papers using pubmed, First search used the keyword "Laser Therapy, Low-level and Atopic dermatitis". Inclusion criteria were last 10 years, RCT, Clinical trial, Human. Second search used the keyword "LLLT and Atopic dermatitis". Inclusion criteria were Human. Third search used the keyword "Laser and Atopic dermatitis". Inclusion criteria was the same as first search. Finally we searched papers using the keyword "Laser and Atopic dermatitis" in NDSL and RISS. Papers not matched with inclusion criteria were excluded. Results : A total 20 studies were found, 14 studies were excluded and 6 studies were selected and analyzed. They turned out to be effective and no serious side-effect, but there was mild side-effect in 2 papers out of 4 papers using high-level laser. Conclusions : Low-level laser and high-level laser therapy, both can be effectively used as an alternative to the treatment of atopic dermatitis. Thus further attention and studies are needed on this topic in order to reduce the side effects and demonstrate the effectiveness clearly.



  1. Lee HS, Kim JS, Pyun BY. Pediatric allergy and Respiratory Disease, Change of Prevalence and the Allergens of Atopic Dermatitis in Children: In between the year of 1992 and 2002. Pediatric allergy and Respiratory Disease. 2002;12(4);263-71.
  2. Choi HY. The Effect of Living Environment and Dietary Habits on Atopic Dermatitis in Children. Sookmyung Women's University. 2011:49.
  3. Tuner J, Hoe L(Author), Jang IS, Shin GB(Translator). Laser Therapy. Seoul:JungDam. 2006:8-9, 43-4, 128-9.
  4. Yu W, Naim JO, Lanzafame RJ. Effects of photostimulation on wound healing in diabetic mice. Laser Surg Med. 1997; 20:56-63.<56::AID-LSM9>3.0.CO;2-Y
  5. Babapour R, Glassberg E, Lask GP. Low-energy laser systems. Clin Dermatol. 1995;13:87-90.
  6. Basford JR. Low intensity laser therapy: still not an established clinical tool. Laser Surg Med. 1995;16:331-42.
  7. Yeo EJ, Han JK, Kim YH. Topical Application of Atopy cream-jawoongo ointment(A-J) of Ointment Inhibits Biostir mite antigen cream induced Atopy Dermatitis by Local Action in Nc/Nga Mice. Journal of the Institute of Oriental Medicine, Daejeon University.
  8. Kim SB, Kim SM, Kim DH. Effects of Baedokhwanbalhyobang(BDHBH) on Immune Modulation in Dermatitis Model of NC/Nga Mice. Journal of the Institute of Oriental Medicine, Daejeon University. 2011;19(2): 101-18.
  9. Kim YH, Han JK. Effect of Kami-Kang HwalSan on atopic dermatitis-Like skin Lesions induced in NC/Nga mice by mite antigen stimulation. Journal of the Institute of Oriental Medicine, Daejeon University. 2007;16(1):81-91.
  10. Bang CK, Choi JJ, Eom DM, Kim DH. The Effects of BGG on Various Immunological Factors Related to Pathogenesis of Allergic Dermatitis in NC/Nga Mice Induced by Der-f. Journal of the Institute of Oriental Medicine, Daejeon University. 2007;16(2):147-69.
  11. Yoon HJ, Yoon JS, Kim DG, Lee JY. The Effects of Low Level Laser Therapy on Decrease of Atopic Dermatitis Symptoms. J Korean Oriental Pediatrics. 2009;23(3):193-206.
  12. Morita H, Kohno J, Hori M, Kitano Y. Clinical Application of Low Reactive Level Laser Therapy for Atopic Dermatitis. Keio J Med. 1993;42(4):174-6.
  13. Nistico SP, Saraceno R, Capriotti E, Felice CD, Chimenti S. Efficacy of Monochromatic Excimer Light (308nm) in the Treatment of Atopic Dermatitis in Adults and Children. Photomed Laser Surg. 2008;26(1):14-8.
  14. Baltas E, Csoma Z, Bodai L, Ignacz F, Dobozy A, Kemeny L. Treatment of atopic dermatitis with the xenon chloride excimer laser. J Eur Acad Dermatol Venereol. 2006 ;20(6):657-60.
  15. Brenninkmeijer EE, Spuls PI, Lindeboom R, van der Wal AC, Bos JD, Wolkerstorfer A. Eximer laser vs. clobetasol propionate 0.05% ointment in prurigo form of atopic dermatitis of atopic dermatitis: a randomized controlled trial, a pilot. British Journal of Dermatology. 2010;163(4):823-31.
  16. Syed S, Weibel L, Kennedy H, Harper JI. A pilot study showing pulse-dye laser treatment improves localized areas of chronic atopic dermatitis. Clinical and Experimental Dermatology. 2007;33(3):243-8.
  17. Kang TJ, Lee SR. The causes and treatment of atopic dermatitis management. BioWave. 2010;12(3):1. Available from: URL: ard=review0&id=2640
  18. Bae CU, Park MY. Do you know herb medicine enzyme? Atopy psoriasis treatment. Seoul: Medical Books. 2008:106-11.
  19. Chung PS, Lee SJ. Biomodulation Effect of the Low-Level Laser Therapy(LLLT). J Clinical Otolaryngol. 2004;15(2):167-73.
  20. Schindl A, Neumann R. Low-intensity laser therapy in an effetive treatment for recurrent herpes simplex infection: Results from a randomized double-blind placebo-controlled study. J Invest Dermatol. 1999;54;2-7.
  21. Goldman JA, Chiapella J, Casey H, Bass N, Graham J, Mcclatchey W. Laser therapy of rheumatoid arthritis. Lasers Surg Med. 1980;1:93-101.
  22. Sung GJ, Choi JH. Laser treatment of skin diseases. The Ulsan Univ. Med. J. 1995; 4(2):8-17.
  23. Iga N, Otsuka A, Tanioka M, Miyachi Y, Kabashima K. Improvement of Anti-TNF-${\alpha}$ Antibody-Induced Palmoplantar Pustular Psoriasis Using a 308-nm Excimer Light. Case Rep Dermatol. 2012;4(3):261-4.
  24. Taibjee SM, Cheung ST, Laube S, Lanigan SW. Controlled study of excimer and pulsed dye lasers in the treatment of psoriasis. Br J Dermatol. 2005;153(5):960-6.

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