Investigative Magnetic Resonance Imaging

Korean Society of Magnetic Resonance in Medicine (대한자기공명의과학회)
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Diffusion Tensor Imaging and Cerebrospinal Fluid Flow Study of Cine Phase Contrast in Normal Cervical Spinal Cords

정상인 경수에 대한 확산텐서영상과 PC기법을 이용한 뇌척수액 속도 측정에 관한 연구

  • Son, B.K. (Department of Medical Imaging Science, Graduate School Inje University) ;
  • Kwak, S.Y. (Department of Biomedical Engineering, and U-Health care Research Center, Inje University) ;
  • Han, Y.H. (Department of Biomedical Engineering, and U-Health care Research Center, Inje University) ;
  • Yoo, J.S. (Division of MRI, Department of Diganostic Radiology, Pusan National University Yangsan Hospital) ;
  • Kim, O.H. (Department of Radiology, Inje University Haeundae Paik Hospital) ;
  • Ko, H.Y. (Department of Rehabilitation Medicine, Pusan National University School of Medicine) ;
  • Mun, C.W. (Department of Medical Imaging Science, Graduate School Inje University)
  • 손봉경 (인제대학교 의료영상과학) ;
  • 곽소영 (인제대학교 의용공학과, UHRC) ;
  • 한용희 (인제대학교 의용공학과, UHRC) ;
  • 유장선 (양산부산대학교병원 MRI실) ;
  • 김옥화 (인제대학교 해운대백병원 영상의학과) ;
  • 고현윤 (부산대학교 의학전문대학원 재활의학교실) ;
  • 문치웅 (인제대학교 의료영상과학)
  • Received : 2013.02.13
  • Accepted : 2013.03.29
  • Published : 2013.06.30
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Abstract

Purpose : We report the results of the various parameters of diffusion tensor imaging (DTI) and CSF flow study of the cervical spinal cord using magnetic resonance (MR) imaging techniques. Materials and Methods: Intramedullary FA and MD were measured in the gray matter and posterior cord of the white matter and both lateral cords of the white matter at the C2-3, C4-5, C5-6 spinal levels. For the CSF flow study, velocity encoding was obtained at the C2-3, C4-5, C5-6 spinal levels. Results: There was a significant difference of the FA and MD between the white matter and gray matter (p < 0.05). The FA of the gray matter was significantly different according to the cervical spinal cord levels (p < 0.05). Otherwise, the FA and MD parameters were not significantly different (p > 0.05). The mean peak systolic velocity and mean peak diastolic velocity were $5.18{\pm}2.00cm/sec$ and $-7.32{\pm}3.18cm/sec$, respectively from C2 to C6 spinal cords. There was no significant difference in these velocities among the cervical spinal cord (p > 0.05). Conclusion: This basic information about DTI and CSF dynamics of the cervical spinal cord may be useful for assessing cervical spinal cord abnormalities using MR imaging.

목적 : 정상인 경수에 대한 내부 부위별, 경수 레벨별 확산텐서영상과 뇌척수액 속도에 대한 정상인 기준을 마련하고자 하였다. 대상 및 방법 : 정상인을 대상으로 3T MRI를 이용하여 영상을 획득하였다. 확산텐서영상은 척수 레벨별로 각각 미리 정의해둔 백질의 후삭, 좌, 우 측삭과 회백질에 관심영역을 정하여 FA, MD에 대한 평균값을 구하였다. PC 기법을 이용한 뇌척수액 속도 측정은 C2-3, C4-5, C5-6 척수레벨을 각각 스캔한 후, 척수 레벨별 최대 수축기 및 이완기 속도를 측정하였다. 결과 : FA 값과 MD 값에서 회백질과 백질의 내부 구조 사이에서는 통계적으로 유의한 차이 (p < 0.05)를 보였다. 경수 레벨별에서는 회백질의 FA 값에서 통계적으로 유의한 차이(p < 0.05)를 보였으며, 나머지 부분에서는 통계적으로 유의한 차이를 보이지 않았다 (p > 0.05). 뇌척수액 속도 측정 결과, 평균 최대 수축기 속도 $5.18{\pm}2.00cm/sec$, 평균 최대 이완기 속도 $-7.32{\pm}3.18cm/sec$ 이었으며, 경수 레벨별로는 통계적으로 유의한 차이를 보이지 않았다 (p > 0.05). 결론 : 정상인에 대한 경수 확산텐서영상의 정량적 수치 및 경수 레벨에 영향을 받지 않는 뇌척수액 속도에 대한 평균치를 알 수가 있었다.

Keywords

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