The Korean journal of internal medicine

  • 제28권6호
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  • Pages.728-731
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  • 2013
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  • 1226-3303(pISSN)
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  • 2005-6648(eISSN)
대한내과학회 (The Korean Association of Internal Medicine)
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A case of Tsutsugamushi disease presenting with nephrotic syndrome

  • Lee, Ju Hyun (Division of Nephrology, Department of Internal Medicine, Yonsei University College of Medicine) ;
  • Lee, Mi Jung (Division of Nephrology, Department of Internal Medicine, Yonsei University College of Medicine) ;
  • Shin, Dong Ho (Division of Nephrology, Department of Internal Medicine, Yonsei University College of Medicine) ;
  • Kang, Shin-Wook (Division of Nephrology, Department of Internal Medicine, Yonsei University College of Medicine) ;
  • Choi, Kyu Hun (Division of Nephrology, Department of Internal Medicine, Yonsei University College of Medicine) ;
  • Yoo, Tae-Hyun (Division of Nephrology, Department of Internal Medicine, Yonsei University College of Medicine)
  • 투고 : 2012.04.16
  • 심사 : 2012.06.29
  • 발행 : 2013.11.01
⟨ 이전 논문 다음 논문 ⟩

초록

Nephrotic syndrome associated with Tsutsugamushi disease has not been previously reported. We are describing a case of Tsutsugamuchi disease presenting with nephrotic syndrome. A 72-year-old woman presented with fever and generalized edema. Laboratory studies revealed a leukocytosis, hypoalbuminemia, and hypercholesterolemia. Her urine protein excretion was 5.4 g/day. The anti-Tsutsugamushi antibody test was strongly positive (1:2,560). A renal biopsy was performed, and pathologic findings revealed membranous glomerulonephritis. The patient′s clinical symptoms improved markedly after treatment with doxycycline.

키워드

참고문헌

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피인용 문헌

  1. IL-33-Dependent Endothelial Activation Contributes to Apoptosis and Renal Injury in Orientia tsutsugamushi -Infected Mice vol.10, pp.3, 2016, https://doi.org/10.1371/journal.pntd.0004467
  2. Clinical manifestations of scrub typhus vol.111, pp.2, 2017, https://doi.org/10.1093/trstmh/trx017
  3. Incidence, risk factors and clinical outcomes of acute kidney injury associated with scrub typhus: a retrospective study of 510 consecutive patients in South Korea (2001–2013) vol.7, pp.3, 2013, https://doi.org/10.1136/bmjopen-2016-013882