Asian Pacific Journal of Cancer Prevention

Asian Pacific Journal of Cancer Prevention (아시아태평양암예방학회)
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Do the Different Reasons for Lactation Discontinuation Have Similar Impact on Future Breast Problems?

  • Ghadiri, Fereshteh (Department of Surgery, Tehran University of Medical Sciences, School of Public Health Tehran University of Medical Sciences) ;
  • Iranpour, Negar (Department of Surgery, Tehran University of Medical Sciences, School of Public Health Tehran University of Medical Sciences) ;
  • Yunesian, Masud (Department of Environmental Health Engineering, School of Public Health Tehran University of Medical Sciences) ;
  • Shadlou, Zahra (Department of Surgery, Tehran University of Medical Sciences, School of Public Health Tehran University of Medical Sciences) ;
  • Kaviani, Ahmad (Department of Surgery, Tehran University of Medical Sciences, School of Public Health Tehran University of Medical Sciences)
  • Published : 2013.10.30
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Abstract

Background: Breast feeding is considered to be mutually beneficial for both mothers and infants, though the effect of lactation problems on development of breast lesions (whether benign or malignant) is not clear. Objectives: This study was conducted to identify possible relations between lactation problems and benign and malignant breast disease. Materials and Methods: 308 patients referred to two referral breast clinics in Tehran, the capital city of IR Iran, between January 2008 and January 2011, were recruited. They were interviewed by a standard questionnaire regarding breast feeding problems. The study population was classified in 3 major groups; breast feeding without any problem, unwillingness to breast feed according to whether mothers' preference not to feed or some breast problems like mastitis, and finally insufficient milk that caused the mothers to feed their babies with formula. Results: Recruiting binary logistic regression method, mother's unwillingness to feed her child by breast milk, and also breast problems such as mastitis and abscess during lactation period showed significant relation with both benign and malignant breast diseases (p value<0.01). Surprisingly, inadequate milk was not associated with any of these conditions. Conclusions: We concluded that lactation problems which involve normal milk drainage from the breast may play an important role in whether the mother wll subsequently develope both benign and malignant pathologies. In contrast in the situation that the production of the milk is not sufficient and there are no intentional or unintentional problems in drainage of the produced milk, future problems would not be more common.

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References

  1. Abou-Dakn M, Scheele M, Strecker JR (2003). Does breast-feeding prevent breast cancer? Zentralbl Gynakol, 125, 48-52. https://doi.org/10.1055/s-2003-40365
  2. Adami HO, Bergstrom R, Lund E, Meirik O (1990). Absence of association between reproductive variables and the risk of breast cancer in young women in Sweden and Norway. Br J Cancer, 62, 122-6. https://doi.org/10.1038/bjc.1990.242
  3. Aguilar Cordero MJ, Gonzalez Jimenez E, Alvarez Ferre J, et al (2010). Breast feeding: an effective method to prevent breast cancer. Nutr Hosp, 25, 954-8.
  4. Akbari A, Razzaghi Z, Homaee F, et al (2011). Parity and breastfeeding are preventive measures against breast cancer in Iranian women. Breast Cancer, 18, 51-5. https://doi.org/10.1007/s12282-010-0203-z
  5. Andrieu N, Goldgar DE, Easton DF, et al (2006). Pregnancies, breast-feeding, and breast cancer risk in the international BRCA1/2 carrier cohort study (IBCCS). J Natl Cancer Inst, 98, 535-44. https://doi.org/10.1093/jnci/djj132
  6. Bernardi S, Londero AP, Bertozzi S, et al (2012). Breast-feeding and benign breast disease. J Obstet Gynaecol, 32, 58-61. https://doi.org/10.3109/01443615.2011.613496
  7. Byers T, Graham S, Rzepka T, Marshall J (1985). Lactation and breast cancer. Evidence for a negative association in premenopausal women. Am J Epidemiol, 121, 664-74. https://doi.org/10.1093/aje/121.5.664
  8. Cohen JM, Hutcheon JA, Julien SG, Tremblay ML, Fuhrer R (2009). Insufficient milk supply and breast cancer risk: a systematic review. PLoS One, 4, 8237. https://doi.org/10.1371/journal.pone.0008237
  9. Hutchinson JN, Muller WJ (2000). Transgenic mouse models of human breast cancer. Oncogene, 19, 6130-7. https://doi.org/10.1038/sj.onc.1203970
  10. Julien SG, Dube N, Read M, et al (2007). Protein tyrosine phosphatase 1B deficiency or inhibition delays ErbB2-induced mammary tumorigenesis and protects from lung metastasis. Nat Genet, 39, 338-46. https://doi.org/10.1038/ng1963
  11. Kim Y, Choi JY, Lee KM, et al (2007). Dose-dependent protective effect of breast-feeding against breast cancer among ever-lactated women in Korea. Eur J Cancer Prev, 16, 124-9. https://doi.org/10.1097/01.cej.0000228400.07364.52
  12. Lambe M, Johansson AL, Altman D, Eloranta S (2009). Mastitis and the risk of breast cancer. Epidemiology, 20, 747-51. https://doi.org/10.1097/EDE.0b013e3181adbb1e
  13. Lipworth L, Bailey LR, Trichopoulos D (2000). History of breast-feeding in relation to breast cancer risk: a review of the epidemiologic literature. J Natl Cancer Inst, 92, 302-12. https://doi.org/10.1093/jnci/92.4.302
  14. MacMahon B, Lin TM, Lowe CR, et al (1970). Lactation and cancer of the breast. A summary of an international study. Bull World Health Organ, 42, 185-94.
  15. Negri E, Braga C, La Vecchia C, et al (1996). Lactation and the risk of breast cancer in an Italian population. Int J Cancer, 67, 161-4. https://doi.org/10.1002/(SICI)1097-0215(19960717)67:2<161::AID-IJC1>3.0.CO;2-R
  16. Newcomb PA (1997). Lactation and breast cancer risk. J Mammary Gland Biol Neoplasia, 2, 311-8. https://doi.org/10.1023/A:1026344707161
  17. Newcomb PA, Egan KM, Titus-Ernstoff L, et al (1999). Lactation in relation to postmenopausal breast cancer. Am J Epidemiol, 150, 174-82. https://doi.org/10.1093/oxfordjournals.aje.a009977
  18. Newcomb PA, Storer BE, Longnecker MP, et al (1994). Lactation and a reduced risk of premenopausal breast cancer. N Engl J Med, 330, 81-7. https://doi.org/10.1056/NEJM199401133300201
  19. No authors listed (1993). Breast feeding and risk of breast cancer in young women. United Kingdom National Case-Control Study Group. BMJ, 307, 17-20. https://doi.org/10.1136/bmj.307.6895.17
  20. No authors listed (1994). Breast-feeding may reduce breastcancer risk. Indian Med Trib, 2, 4.
  21. No authors listed (2002). Breast cancer and breastfeeding: collaborative reanalysis of individual data from 47 epidemiological studies in 30 countries, including 50302 women with breast cancer and 96973 women without the disease. Lancet, 360, 187-95. https://doi.org/10.1016/S0140-6736(02)09454-0
  22. Parkin DM (2011). 15. Cancers attributable to reproductive factors in the UK in 2010. Br J Cancer, 105, 73-6. https://doi.org/10.1038/bjc.2011.488
  23. Sakai T (2001). Does breastfeeding reduce risk for breast cancer? A short lesson in evidence-based practice. MCN Am J Matern Child Nurs, 26, 42-5. https://doi.org/10.1097/00005721-200101000-00011
  24. Shema L, Ore L, Ben-Shachar M, Haj M, Linn S (2007). The association between breastfeeding and breast cancer occurrence among Israeli Jewish women: a case control study. J Cancer Res Clin Oncol, 133, 539-46. https://doi.org/10.1007/s00432-007-0199-8
  25. Wiener JR, Kerns BJ, Harvey EL, et al (1994). Overexpression of the protein tyrosine phosphatase PTP1B in human breast cancer: association with p185c-erbB-2 protein expression. J Natl Cancer Inst, 86, 372-8. https://doi.org/10.1093/jnci/86.5.372
  26. Woodman I (2002). Breast feeding reduces risk of breast cancer, says study. BMJ, 325, 184. https://doi.org/10.1136/bmj.325.7357.184
  27. Yang CP, Weiss NS, Band PR, et al. (1993). History of lactation and breast cancer risk. Am J Epidemiol, 138, 1050-6.
  28. Yoo KY, Tajima K, Kuroishi T, et al (1992). Independent protective effect of lactation against breast cancer: a case-control study in Japan. Am J Epidemiol, 135, 726-33.

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