Journal of Biomedical Engineering Research (대한의용생체공학회:의공학회지)

The Korean Society of Medical and Biological Engineering (대한의용생체공학회)
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Modulation in Action Potentials of Rat Hippocampal Neurons Measured on Multi-Channel Electrodes During Ultrasound Stimulation

다채널 전극을 이용한 초음파 자극 시 쥐 해마 신경 세포의 활동 전위 검출

  • Han, H.S. (Department of Biomedical Engineering, Kyung Hee University) ;
  • Jeon, H.J. (Department of Biomedical Engineering, Kyung Hee University) ;
  • Hwang, S.Y. (Department of Electronics Engineering, College of Engineering, Ewha Womans University) ;
  • Lee, Y.N. (Department of Electronics Engineering, College of Engineering, Ewha Womans University) ;
  • Byun, K.M. (Department of Biomedical Engineering, Kyung Hee University) ;
  • Jun, S.B. (Department of Electronics Engineering, College of Engineering, Ewha Womans University) ;
  • Kim, T.S. (Department of Biomedical Engineering, Kyung Hee University)
  • 한희석 (경희대학교 생체의공학과) ;
  • 전현재 (경희대학교 생체의공학과) ;
  • 황서영 (이화여자대학교 전자공학과) ;
  • 이예나 (이화여자대학교 전자공학과) ;
  • 변경민 (경희대학교 생체의공학과) ;
  • 전상범 (이화여자대학교 전자공학과) ;
  • 김태성 (경희대학교 생체의공학과)
  • Received : 2013.07.18
  • Accepted : 2013.11.29
  • Published : 2013.12.31
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Abstract

It is known that ultrasound affects action potentials in neurons, but the underlying principles of ultrasonic neural stimulation are not clearly elucidated yet. In this study, we measured the action potentials of rat hippocampal neurons cultured on multi-electrode arrays during ultrasound stimulation. From most of electrodes, it was observed that the ultrasound stimulation increased the frequencies of action potentials (i.e., spikes) during ultrasound stimulation.

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References

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