The Korean Journal of Pesticide Science (농약과학회지)

The Korean Society of Pesticide Science (한국농약과학회)
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Evaluation of Skin & Eye Irritation of Plant Extracts, Neem and Sophora

유기농업자재 중 님과 고삼 추출물의 피부 및 안점막자극성

  • Oh, Jin-A (Chemical Safety Division, Department of Agro-Food Safety, National Academy of Agricultural Science, Rural Development Administration) ;
  • Choi, Jin-Hee (Chemical Safety Division, Department of Agro-Food Safety, National Academy of Agricultural Science, Rural Development Administration) ;
  • Choe, Mi-Seon (Chemical Safety Division, Department of Agro-Food Safety, National Academy of Agricultural Science, Rural Development Administration) ;
  • Kim, Jin-Hyo (Chemical Safety Division, Department of Agro-Food Safety, National Academy of Agricultural Science, Rural Development Administration) ;
  • Paik, Min-Kyoung (Chemical Safety Division, Department of Agro-Food Safety, National Academy of Agricultural Science, Rural Development Administration) ;
  • Park, Kyung-Hun (Chemical Safety Division, Department of Agro-Food Safety, National Academy of Agricultural Science, Rural Development Administration) ;
  • You, Are-Sun (Agro-Material Safety Evaluating Division, Department of Agro-Food Safety, National Academy of Agricultural Science, Rural Development Administration) ;
  • Lee, Je-Bong (Agro-Material Safety Evaluating Division, Department of Agro-Food Safety, National Academy of Agricultural Science, Rural Development Administration) ;
  • Kim, Doo-Ho (Chemical Safety Division, Department of Agro-Food Safety, National Academy of Agricultural Science, Rural Development Administration)
  • 오진아 (농촌진흥청 국립농업과학원 농산물안전성부 화학물질안전과) ;
  • 최진희 (농촌진흥청 국립농업과학원 농산물안전성부 화학물질안전과) ;
  • 최미선 (농촌진흥청 국립농업과학원 농산물안전성부 화학물질안전과) ;
  • 김진효 (농촌진흥청 국립농업과학원 농산물안전성부 화학물질안전과) ;
  • 백민경 (농촌진흥청 국립농업과학원 농산물안전성부 화학물질안전과) ;
  • 박경훈 (농촌진흥청 국립농업과학원 농산물안전성부 화학물질안전과) ;
  • 유아선 (농촌진흥청 국립농업과학원 농산물안전성부 농자재평가과) ;
  • 이제봉 (농촌진흥청 국립농업과학원 농산물안전성부 농자재평가과) ;
  • 김두호 (농촌진흥청 국립농업과학원 농산물안전성부 화학물질안전과)
  • Received : 2013.10.25
  • Accepted : 2013.11.29
  • Published : 2013.12.31
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Abstract

This study was performed to evaluate the acute skin and eye irritation of plant extracts (neem and sophora) against rabbit. The result of skin irritation test indicated that neem extracts and sophora extracts were not irritant. For eye irritation test, the result showed no irritation for neem extracts. Sophora extracts have a severe eye irritation and the symptoms have been reduced to day 3. Thus, safety guidelines for agricultural workers is considered to be needed when sophora extracts is used as an organic agricultural materials.

본 연구는 병해충 관리용 유기농업자재 허용물질로 지정된 식물추출물 중 님 추출물(미얀마산, 인도산)과 고삼추출물(중국산)의 독성 평가를 위해 피부자극성과 안점막자극성시험을 수행하였다. 시험결과, 원산지가 다른 님 추출물 2종은 모두 피부자극성과 안점막자극성이 없는 것으로 평가되었고, 고삼 추출물은 피부자극성은 없었고 안점막자극성이 강도로 나타났으나 시간이 경과함에 따라 자극이 경감하는 것으로 평가됐다. 따라서 안점막자극성이 강한 것으로 평가된 고삼 추출물을 유기농업자재로 사용할 때 농작업자에 대한 안전대책이 필요한 것으로 판단된다.

Keywords

References

  1. EFSA (2011) Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin.
  2. Lee, J. B., M. H. Jeong, H. J. Sung, H. K. Lee and J. S. Yang (2001) Acute toxicity response caused by mixture or tank mix of several insecticides. The Korean Journal of Pesticide Science. 5:57-61.
  3. Kang, W. T. (2012) A study on the insecticidal effect and biological safety of plant extracts. Kyungnam University.
  4. Korea Eco-friendly Agro-Materials Association (2012) Guidelines for standard use of Eco-friendly agro-materials.
  5. Lee, G. S., E. S. Kim, S. I. Cho, J. H. Kim, G. Choi, Y. S. Ju, S. H. Park, S. I. Jeong, H. J. Kim and H. J. Kim (2010) Antibacterial and synergistic activity of prenylated chalcone isolated from the roots of Sophora flavescens, Journal of the Korean Society for Applied Biological Chemistry 53(3): 290-296. https://doi.org/10.3839/jksabc.2010.045
  6. Mao, L. and H. Gregg (2007) Antifeedant activity and acute and residual toxicity of alkaloids from Sophora flavescens (Leguminosae) against formosan subterranean termites (Isoptera: Rhinotermitidae). Journal of Economic Entomology., 100:866-870. https://doi.org/10.1603/0022-0493(2007)100[866:AAAAAR]2.0.CO;2
  7. Mordue, A. J., M. S. L. Simmonds, S. V. Ley, W. M. Blaney, W. Mordue, M. Nasiruddin and A. J. Nisbet (1998) Actions of azadirachtin, a plant allelochemical, against insects. Journal of Pesticide Science 54:277-284. https://doi.org/10.1002/(SICI)1096-9063(1998110)54:3<277::AID-PS801>3.0.CO;2-I
  8. Rural Development Administration (2012).

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