Journal of Veterinary Clinics (한국임상수의학회지)

The Korean Society of Veterinary Clinics (한국임상수의학회)
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Elevation of Plasma NT-proBNP Concentration in a Korean Jindo Dog Infected with Dirofilaria immitis

심장사상충 감염 진도견에서 혈장 NT-proBNP 농도 증가 증례

  • Hwang, Soo-Hyen (Laboratory of Veterinary Internal Medicine, College of Veterinary Medicine, Chungnam National University) ;
  • Park, Hyung-Jin (Laboratory of Veterinary Internal Medicine, College of Veterinary Medicine, Chungnam National University) ;
  • Seo, Kyoung-Won (Laboratory of Veterinary Internal Medicine, College of Veterinary Medicine, Chungnam National University) ;
  • Lee, Sang-Eun (Division of Malaria & Parasitic Diseases, Korea National Institute of Health, Korea Centers for Disease Control and Prevention) ;
  • Song, Kun-Ho (Laboratory of Veterinary Internal Medicine, College of Veterinary Medicine, Chungnam National University)
  • Accepted : 2013.11.20
  • Published : 2013.12.31
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Abstract

The aim of this study is to report the observed elevation of plasma N-terminal pro-B-type natriuretic peptide (NT proBNP) concentration in a Korean Jindo Dog infected with Dirofilaria immitis. Evaluation of the animal included physical examination, thoracic radiography, ELISA kit ($PetCheck^{(R)}$, IDEXX Laboratories, USA) test and plasma NT-proBNP evaluation. The infected animal's NT-proBNP concentration was compared with those of 5 normal dogs of the same age, sex, and breed; the affected Korean Jindo dog had increased plasma NT-proBNP. To the best our knowledge, this is the first report of NT-proBNP elevation in a Korean Jindo dog with dirofilariasis.

본 증례는 충남대학교 수의과대학 부속동물병원에 내원한 심장사상충에 중감염된 2세, 암컷의 진도견에서 혈장 NT-pro BNP농도를 측정하였다. 심장사상충 감염은 신체검사, 혈액검사, ELISA 키트검사 및 영상진단검사 등으로 진단하였다. 본 증례 진도견의 혈장 NT-pro BNP농도는 심장사상충에 감염되지 않고, 다른 질병도 없는 5마리(모두2세, 모두 암컷)의 정상견과 비교하였을 때, 상대적으로 매우 높은 수치를 나타내었다 (정상견 평균: 373 pmol/L, 본 증례: 2,950 pmol/L). 본 연구는 우리가 아는 한 심장사상충에 감염된 진도견에서 혈장 NT-pro BNP농도를 측정하여 보고한 최초의 증례보고이다.

Keywords

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