Journal of Acupuncture Research

Korean Acupuncture & Moxibustion Medicine Society (대한침구의학회)
권호 표지
DOI QR코드

DOI QR Code

A Clinical Case Study on the Effects of Acupuncture Therapy and Ecklonia Cava Extract on Sleep Disturbances in ALS Patients

수면 장애를 동반한 근위축성 측삭 경화증 환자에 대한 감태추출물과 침치료 병행 치험 1례

  • Lee, Sang Mi (Department of Acupuncture & Moxibustion Medicine, Wonkwang Gwangju Oriental Medical Hospital) ;
  • Jeong, Ho Hyun (Department of Acupuncture & Moxibustion Medicine, Wonkwang Gwangju Oriental Medical Hospital) ;
  • Lee, Jong Cheol (Department of Acupuncture & Moxibustion Medicine, Wonkwang Gwangju Oriental Medical Hospital) ;
  • Park, Man Yong (Department of Acupuncture & Moxibustion Medicine, Wonkwang Gwangju Oriental Medical Hospital) ;
  • Kim, Sung Chul (Department of Acupuncture & Moxibustion Medicine, Wonkwang Gwangju Oriental Medical Hospital)
  • 이상미 (원광대학교 광주한방병원 침구의학과) ;
  • 정호현 (원광대학교 광주한방병원 침구의학과) ;
  • 이종철 (원광대학교 광주한방병원 침구의학과) ;
  • 박만용 (원광대학교 광주한방병원 침구의학과) ;
  • 김성철 (원광대학교 광주한방병원 침구의학과)
  • Received : 2013.11.11
  • Accepted : 2013.12.02
  • Published : 2013.12.20
Download PDF
⟨ Previous Next ⟩

Abstract

Objectives : The purpose of this study was to observe the clinical effects of acupuncture therapy and Ecklonia cava extract on sleep disturbance in ALS patients. Methods : In this study one patient received acupuncture therapy and took Ecklonia cava extract. The effects of the combined administration of these treatments were evaluated using Numeric Rating Scale and Pittsburgh Sleep Quality Index. Results : The NRS score for sleep disturbance decreased from 10 to 1 and the PSQI score decreased from between 12~13 to 8. After treatment, the patient stopped taking sleeping pills and antidepressant. Conclusions : Combined administration of acupuncture therapy and Ecklonia cava extract could be effective in improving sleep disturbances in ALS patient.

Keywords

References

  1. Han TR, Bang MS. Rehabilitation medicine. Seoul : Gun-ja. 2011 : 697.
  2. Kim SH. Diagnosis and Therapeutic Strategies of Amyotrophic Lateral Sclerosis. Hanyang Medical Reviews. 2006 ; 26(1) : 45-51.
  3. Young C, Tedman BM, Williams IR. Disease Progression and Perception of Health in Patients with Motor Neuron Disease. Journal of neurological Science. 1995 ; 129(supplement) : 50-3. https://doi.org/10.1016/0022-510X(95)00062-7
  4. Daniele Lo Coco, Paola Mattalino, Rossella Spatarol, Alfredo Mattaliano, Vincenzo La Bella. Sleep- wake Disturbances in Patients with Amyotrophic Lateral Sclerosis. Journal of Neurol Neurosurg Psychiatry. 2011 ; 82(8) : 839-42. https://doi.org/10.1136/jnnp.2010.228007
  5. Kirkwood CK. Management of Insomnia. J Am Pham Assoc. 1999 ; 39(5) : 688-96.
  6. Hong HW, Lee SD, Gam CW, Park DI. Clinical Study of Sanjoin-Tang on Insomnia Patients with Cerebrovascular Accident. The Journal of Oriental Physiology & Pathology. 2004 ; 18(6) : 1927-32.
  7. Ryu SH, Yang DJ, Cho KH, Kim YS. The Effect of Hwangyeonhaedogtang Gamibang on Insomnia in Stroke 3 Case Report. The Journal of Oriental Medicine. 2001 ; 22(2) : 120-7.
  8. Kim JW, Ahn DJ, Wang DJ, Lee SY, Kang HW. Clinical Study of 20 Cases of insomnia Patients with Auricular Acupuncture Therapy. The Journal of Oriental Neuropsychiatry. 2004 ; 15(1) : 219-30.
  9. Han C, Kim JH, Ryu KJ, Ahn GS, Kwon SR. A Clinical Report on Insomnia Following Hospitalization improved by the Chuna Manual Relaxation Therapy. The Journal of Oriental Neuropsychiatry. 2008 ; 19(3) : 309-17.
  10. Jung HH. The Effect of Psychodynamic Group Psychotherapy for Sleep problems on Depression, Anxiety, and Sleep Quality. Seoul : Seoul Graduate School of Buddhism. 2005. Korean.
  11. Kim MY, Cho SH, Lee SM, Jung SJ, Park KS. Eldery Sleep Pattern and Disturbing Factors Before and After Hospitalizaion. The Journal of Korean Academy of Nursing. 1987 ; 26(3) : 15-20.
  12. Milne B. Sleep Wake Disorders and What We Can Do About Them. The Journal of Canadian Nurse. 1982 ; 78(4) : 24-7.
  13. Fuller J, Schaller-Ayers J. Health Assessment: A Nursing Approach. Philadelphia Lippincott. 2000 : 52-4.
  14. Kirstie NA, Andrew JB. Sleep Disturbance in Mental Health Problems and Neurodegenerative Disease. The Journal of Nature of Science of Sleep. 2013 ; 31(5) : 68-70.
  15. The Acupuncture and Moxibustion Medicine Textbook Compilation Committee. The Acupuncture and Moxibustion 3rd 2nd Ed. Seoul : Jipmoondang. 2008 : 393.
  16. Le QT, Li Y, Qian ZJ, Kim MM, Kim SK. Inhibitory Effects of Polyphenols Isolated from Marine Alga Ecklonia cava on Histamine Release. Process Biochemistry. 2009 ; 44(2) : 168-76. https://doi.org/10.1016/j.procbio.2008.10.002
  17. Kong CS, Kim JA, Yoon NY, Kim SK. Induction of Aoptosis by Phloroglucinol Derivative from Eclonia Cava in MCF-7 Human Breast Cancer Cells. Food and Chemical Toxicology. 2009 ; 47 : 1653-58. https://doi.org/10.1016/j.fct.2009.04.013
  18. Shin HC, Kim SH, Park YJ, Lee BH, Hwang HJ. Effects of 12-week Oral Supplementation of Ecklonia cava Polyphenols on Anthropometric and Blood Lipid Parametners in Overweight Korean Individuals: A Double-blind Randomized Clinical Trial. Phytotherapy research. 2011 ; 26(3) : 363-68.
  19. Cho SM, Yang HJ, Jeon YJ et al. Phlorotannins of the Edible Brown Seaweed Ecklonia cava Kjellman Induce Sleep via Positive Allosteric Modulation of Gamma aminobutyric Acid Type A-Benzodiazepine Receptor: A novel Neurological Activity of Seaweed Polyphenols. The journal of Food Chemistry. 2012 : 132(3) : 1133-42. https://doi.org/10.1016/j.foodchem.2011.08.040
  20. Cho SM, Han DS, Kim SB et al. Depressive Effects on the Central Nervous System and Underlying Mechanism of the Enzymatic Extract and Its Phlorotannin-Rich Fraction from Ecklonia cava Edible Brown Seaweed. Biosci Biotechnol Biochem. 2012 ; 76(1) : 163-8. https://doi.org/10.1271/bbb.110702

Cited by

  1. 근위축성 측삭경화증의 한방치료에 관한 문헌적 고찰연구 vol.32, pp.4, 2015, https://doi.org/10.13045/acupunct.2015068