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Spinal Intramedullary Ependymal Cysts : A Case Report and Review of the Literature

  • Park, Chang-Hyun (Department of Neurosurgery, Seoul National University Hospital, Seoul National University College of Medicine) ;
  • Hyun, Seung-Jae (Department of Neurosurgery, Seoul National University Bundang Hospital, Seoul National University College of Medicine) ;
  • Kim, Ki-Jeong (Department of Neurosurgery, Seoul National University Bundang Hospital, Seoul National University College of Medicine) ;
  • Kim, Hyun-Jib (Department of Neurosurgery, Seoul National University Bundang Hospital, Seoul National University College of Medicine)
  • 투고 : 2012.04.09
  • 심사 : 2012.06.18
  • 발행 : 2012.07.28

초록

We report a rare case of a spinal intramedullary ependymal cyst in a 46-year-old female and review the 17 pathologically proven cases in the literature. The patient presented with a two-week history of gradually increasing tingling in her left posterior thigh and calf. A preoperative magnetic resonance image revealed a well-defined intramedullary cystic lesion on the ventral side of the spinal cord at the T11 to T12 levels. The lesion was hyper intense in T2-weighted images and hypointense in T1-weighted. The patient underwent a right-side hemilaminectomy at the T11 to T12 levels and fenestration of the cyst wall. After having the cyst wall partially removed and communication established between the cyst and the subarachnoid space, the patient improved neurologically. A histological study of the surgical specimens revealed that the cyst wall consisted of glial cells lined by a simple cuboidal to columnar epithelium. An immunohistochemical examination of the cells lining the cyst wall was positive for S-100 protein, glial fibrillary acidic protein, epithelial membrane antigen, and cytokeratin. We suggest that the optimal treatment of intramedullary ependymal cysts creates adequate communication between the cyst and the subarachnoid space.

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참고문헌

  1. Chhabra R, Bansal S, Radotra BD, Mathuriya SN : Recurrent intramedullary cervical ependymal cyst. Neurol India 51 : 111-113, 2003
  2. Dharker SR, Kanhere S, Dharker RS : Intramedullary epithelial cyst of the spinal cord. Surg Neurol 12 : 443-444, 1979
  3. Findler G, Hadani M, Tadmor R, Bubis JJ, Shaked I, Sahar A : Spinal intradural ependymal cyst : a case report and review of the literature. Neurosurgery 17 : 484-486, 1985 https://doi.org/10.1227/00006123-198509000-00015
  4. Fortuna A, Mercuri S : Intradural spinal cysts. Acta Neurochir (Wien) 68 : 289-314, 1983 https://doi.org/10.1007/BF01401186
  5. Iwahashi H, Kawai S, Watabe Y, Chitoku S, Akita N, Fuji T, et al. : Spinal intramedullary ependymal cyst : a case report. Surg Neurol 52 : 357-361, 1999 https://doi.org/10.1016/S0090-3019(99)00097-X
  6. Kato M, Nakamura H, Suzuki E, Terai H, Wakasa K, Wakasa T, et al. : Ependymal cyst in the lumbar spine associated with cauda equina compression. J Clin Neurosci 15 : 827-830, 2008 https://doi.org/10.1016/j.jocn.2006.12.020
  7. Kumar R, Nayak SR, Krishnani N, Chhabra DK : Spinal intramedullary ependymal cyst. Report of two cases and review of the literature. Pediatr Neurosurg 35 : 29-34, 2001 https://doi.org/10.1159/000050382
  8. Lalitha AV, Rout P, D Souza F; Shailesh, Rao S : Spinal intramedullary neuroepithelial (ependymal) cyst. A rare cause of treatable acute para paresis. Indian J Pediatr 73 : 945-946, 2006 https://doi.org/10.1007/BF02859294
  9. Morest DK, Silver J : Precursors of neurons, neuroglia, and ependymal cells in the CNS : what are they? Where are they from? How do they get where they are going? Glia 43 : 6-18, 2003 https://doi.org/10.1002/glia.10238
  10. Nagano S, Ijiri K, Kawabata R, Zenmyo M, Yone K, Kitajima S, et al. : Ependymal cyst in the conus medullaris. J Clin Neurosci 17 : 272-273, 2010 https://doi.org/10.1016/j.jocn.2009.05.026
  11. Pagni CA, Canavero S, Vinattieri A, Forni M : Intramedullary spinal ependymal cyst : case report. Surg Neurol 35 : 325-328, 1991 https://doi.org/10.1016/0090-3019(91)90014-Z
  12. Robertson DP, Kirkpatrick JB, Harper RL, Mawad ME : Spinal intramedullary ependymal cyst. Report of three cases. J Neurosurg 75 : 312-316, 1991 https://doi.org/10.3171/jns.1991.75.2.0312
  13. Rousseau M, Lesoin F, Combelles G, Krivosic Y, Warot P : An intramedullary ependymal cyst in a 71-year-old woman. Neurosurgery 13 : 52-54, 1983 https://doi.org/10.1227/00006123-198307000-00010
  14. Saito K, Morita A, Shibahara J, Kirino T : Spinal intramedullary ependymal cyst : a case report and review of the literature. Acta Neurochir (Wien) 147 : 443-446; discussion 446, 2005 https://doi.org/10.1007/s00701-004-0477-z
  15. Sharma BS, Banerjee AK, Khosla VK, Kak VK : Congenital intramedullary spinal ependymal cyst. Surg Neurol 27 : 476-480, 1987 https://doi.org/10.1016/0090-3019(87)90257-6
  16. Takci E, Sengul G, Keles M : Spinal intramedullary ependymal cyst and tethered cord in an adult. Case report. J Neurosurg Spine 4 : 506-508, 2006 https://doi.org/10.3171/spi.2006.4.6.506

피인용 문헌

  1. Clinical characteristics and surgical outcomes of spinal intramedullary ependymal cysts vol.156, pp.2, 2012, https://doi.org/10.1007/s00701-013-1964-x
  2. Coexisting intramedullary schwannoma with an ependymal cyst of the conus medullaris: A case report vol.9, pp.2, 2015, https://doi.org/10.3892/ol.2014.2786
  3. Co-existing spinal intradural ependymal cyst and sacral Tarlov cyst in adult-onset tethered cord syndrome with syringomyelia: Case report and literature review vol.7, pp.26, 2012, https://doi.org/10.4103/2152-7806.191083
  4. Intracranial glioependymal (neuroglial) cysts: a systematic review vol.160, pp.7, 2018, https://doi.org/10.1007/s00701-018-3566-0
  5. Comprehensive Review of Spinal Neurenteric Cysts with a Focus on Histopathological Findings vol.10, pp.9, 2012, https://doi.org/10.7759/cureus.3379
  6. Intramedullary spinal tumor-like lesions vol.60, pp.8, 2019, https://doi.org/10.1177/0284185118809540