Bulletin of the Korean Chemical Society

Korean Chemical Society (대한화학회)
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2,4-Diaryl-5H-chromeno [4,3-b]pyridines: Synthesis, Topoisomerase I and II Inhibitory Activity, and Cytotoxicity

  • Received : 2012.03.07
  • Accepted : 2012.06.04
  • Published : 2012.09.20
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Abstract

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References

  1. Cummings, J.; Smyth, J. F. Ann. Oncol. 1993, 4, 533.
  2. Holden, J. A. Curr. Med. Chem. Anticancer Agent 2001, 1, 1. https://doi.org/10.2174/1568011013354859
  3. Topcu, Z. J. Clin. Pharm. Ther. 2001, 26, 405. https://doi.org/10.1046/j.1365-2710.2001.00368.x
  4. Zhao, L. X.; Kim, T. S.; Ahn, S. H.; Kim, T. H.; Kim, E. K.; Cho, W. J.; Choi, H. S.; Lee, C. S.; Kim, J. A.; Jeong, T. C.; Chang, C.-j.; Lee, E.-S. Bioorg. Med. Chem. Lett. 2001, 11, 2659. https://doi.org/10.1016/S0960-894X(01)00531-5
  5. Zhao, L. X.; Moon, Y. S.; Basnet, A.; Kim, E. K.; Jahng, Y.; Park, J. G.; Jeong, T. C.; Cho, W. J.; Choi, S. U.; Lee, C. O.; Lee, S. Y.; Lee, C. S.; Lee, E.-S. Bioorg. Med. Chem. Lett. 2004, 14, 1333. https://doi.org/10.1016/j.bmcl.2003.11.084
  6. Zhao, L. X.; Sherchan, J.; Park, J. K.; Jahng, Y.; Jeong, B. S.; Jeong, T. C.; Lee, C. S.; Lee, E.-S. Arch. Pharm. Res. 2006, 29, 1091. https://doi.org/10.1007/BF02969297
  7. Basnet, A.; Thapa, P.; Karki, R.; Na, Y.; Jahng, Y.; Jeong, B. S.; Jeong, T. C.; Lee, C. S.; Lee, E.-S. Bioorg. Med. Chem. 2007, 15, 4351. https://doi.org/10.1016/j.bmc.2007.04.047
  8. Son, J. K.; Zhao, L. X.; Basnet, A.; Thapa, P.; Karki, R.; Na, Y., Jahng, Y.; Jeong, T. C.; Jeong, B. S.; Lee, C. S.; Lee, E.-S. Eur. J. Med. Chem. 2008, 43, 675. https://doi.org/10.1016/j.ejmech.2007.05.002
  9. Thapa, P.; Karki, R.; Basnet, A.; Thapa, U.; Choi, H. Y.; Na, Y.; Jahng, Y.; Lee, C. S.; Kwon, Y.; Jeong, B. S.; Lee, E.-S. Bull. Korean Chem. Soc. 2008, 29, 1605. https://doi.org/10.5012/bkcs.2008.29.8.1605
  10. Basnet, A.; Thapa, P.; Karki, R.; Choi, H. Y.; Choi, J. H.; Yun, M.; Jeong, B. S.; Jahng, Y.; Na, Y.; Cho, W. J.; Kwon, Y.; Lee, C. S.; Lee, E.-S. Bioorg. Med. Chem. Lett. 2010, 20, 42. https://doi.org/10.1016/j.bmcl.2009.11.041
  11. Thapa, P.; Karki, R.; Thapa, U.; Jahng, Y.; Jung, M. J.; Nam, J. M.; Na, Y.; Kwon, Y.; Lee, E.-S. Bioorg. Med. Chem. 2010, 18, 377. https://doi.org/10.1016/j.bmc.2009.10.049
  12. Thapa, P.; Karki, R.; Choi, H. Y.; Choi, J. H.; Yun, M.; Jeong, B. S.; Jung, M. J.; Nam, J. M.; Na, Y.; Cho, W. J.; Kwon, Y.; Lee, E.-S. Bioorg. Med. Chem. 2010, 18, 2245. https://doi.org/10.1016/j.bmc.2010.01.065
  13. Karki, R.; Thapa, P.; Kang, M. J.; Jeong, T. C.; Nam, J. M.; Kim, H. L.; Na, Y.; Cho, W. J.; Kwon, Y.; Lee, E.-S. Bioorg. Med. Chem. 2010, 18, 3066. https://doi.org/10.1016/j.bmc.2010.03.051
  14. Karki, R.; Thapa, P.; Kwon, Y.; Lee, E.-S. Bull. Korean Chem. Soc. 2010, 31, 1747.
  15. R. Karki, R.; Thapa, P.; Yoo, H. Y.; Kadayat, T. M.; Park, P. H.; Na, Y.; Lee, E.; Jeon, K. H.; Cho, W. J.; Choi, H.; Kwon, Y.; Lee, E.-S. Eur. J. Med. Chem. 2012, 49, 219. https://doi.org/10.1016/j.ejmech.2012.01.015
  16. Jeong, B. S.; Choi, H. Y.; Thapa, P.; Karki, R.; Lee, E.; Nam, J. M.; Na, Y.; Ha, E. M.; Kwon, Y.; Lee, E.-S. Bull. Korean Chem. Soc. 2010, 32, 303.
  17. Thapa, U.; Thapa, P.; Karki, R.; Yun, M.; Choi, J. H.; Jahng, Y.; Lee, E.; Jeon, K. H.; Na, Y.; Ha, E. M.; Cho, W. J.; Kwon, Y.; Lee, E.-S. Eur. J. Med. Chem. 2011, 46, 3201. https://doi.org/10.1016/j.ejmech.2011.04.029
  18. Thapa, P.; Karki, R.; Yoo, H. Y.; Park, P. H.; Lee, E.; Jeon, K. H.; Na, Y.; Cho, W. J.; Kwon, Y.; Lee, E.-S. Bioorg. Chem. 2012, 40, 67. https://doi.org/10.1016/j.bioorg.2011.09.001
  19. Vu, A. T.; Campbell, A. N.; Harris, H. A.; Unwalla, R. J.; Manas, E. S.; Mewshaw, R. E. Bioorg. Med. Chem. Lett. 2007, 17, 4053. https://doi.org/10.1016/j.bmcl.2007.04.068
  20. Cheng, J. F.; Ishikawa, A.; Ono, Y.; Arrhenius, T.; Nadzan, A. Bioorg. Med. Chem. Lett. 2003, 13, 3647. https://doi.org/10.1016/j.bmcl.2003.08.025
  21. Gebhardt, P.; Dornberger, K.; Gollmick, F. A.; Grafe, U.; Hartl, A.; Schlegel, B.; Hertweck, C. Bioorg. Med. Chem. Lett. 2007, 17, 2558. https://doi.org/10.1016/j.bmcl.2007.02.008
  22. Jahng, Y.; Zhao, L. X.; Moon, Y. S.; Basnet, A.; Kim, E. K.; Chang, H. W.; Ju, H. K.; Jeong, T. C.; Lee, E.-S. Bioorg. Med. Chem. Lett. 2004, 14, 2559. https://doi.org/10.1016/j.bmcl.2004.02.099
  23. Krohnke, F. Synthesis 1976, 1.

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