Data Mining and Construction of Database Concerning Effects of Vitis Genus

산머루 관련 정보수집 및 데이터베이스의 구축

  • Kim, Min-A (Department of Physiology, College of Oriental Medicine, Kyunghee University) ;
  • Jo, Yun-Ju (Department of Physiology, College of Oriental Medicine, Kyunghee University) ;
  • Shin, Jee-Young (Department of Physiology, College of Oriental Medicine, Kyunghee University) ;
  • Shin, Min-Kyu (Department of Physiology, College of Oriental Medicine, Kyunghee University) ;
  • Bae, Hyun-Su (Department of Physiology, College of Oriental Medicine, Kyunghee University) ;
  • Hong, Moo-Chang (Department of Physiology, College of Oriental Medicine, Kyunghee University) ;
  • Kim, Yang-Seok (Department of Physiology, College of Oriental Medicine, Kyunghee University)
  • 김민아 (경희대학교 한의과대학 생리학교실) ;
  • 조윤주 (경희대학교 한의과대학 생리학교실) ;
  • 신지영 (경희대학교 한의과대학 생리학교실) ;
  • 신민규 (경희대학교 한의과대학 생리학교실) ;
  • 배현수 (경희대학교 한의과대학 생리학교실) ;
  • 홍무창 (경희대학교 한의과대학 생리학교실) ;
  • 김양석 (경희대학교 한의과대학 생리학교실)
  • Received : 2012.05.30
  • Accepted : 2012.07.10
  • Published : 2012.08.25

Abstract

The database for the oriental medicine had been existed in documentation in past times and it has been developed to the database type for random accesses in the information society. However, the aspects of the database are not so diversified and the database for the bio herbal material exists in widened type dictionary style. It is a situation that the database which handles the in-depth raw herbal medicines is not sufficient in its quantity and quality. Korean wild grape is a deciduous plant categorized into the Vitaceae and it was found experimentally that it has various medical effects. It is one of the medical materials with higher potentiality of academic study and commercialization recently because it has a bigger possibility to be applied into diverse industrial fields including the medical product for health, food and beauty. We constituted the cooperative system among the Muju cluster business group for Korean mountain wild grapes, Physiology Laboratory in Kyung Hee University Oriental Medicine and Medical Classics Laboratory in Kyung Hee University Oriental Medicine with a view to focusing on such potentiality and a database for Korean wild grapes was made a touchstone for establishing the in-depth database for the single bio medical materials. First of all, the literatures based on the North East Asia in ancient times had been categorized into the classical literature (Korean literature published by government organization, Korean classical literature, Chinese classical literature and classical literature fro Korean and Chinese oriental medicine) and modern literature (Modern literature for oriental medicine, modern literature for domestic and foreign herbal medicine) to cover the eastern and western research records and writings related to Korean wild grapes and the text-mining work has been performed through the cooperation system with the Medical Classics Laboratory in Kyung Hee University Oriental Medicine. First of all, the data for the experiment and theory for Korean wild grape were collected for the Medline database controlled by the Parliament Library of USA to arrange the domestic and foreign theses with topic for Korean wild grapes and the network hyperlink function and down load function were mounted for self-thesis searching function and active view based on the collected data. The thesis searching function provides various auxiliary functions and the searching is available according to the diverse searching/queries such as the name of sub species of Korean wild grape, the logical intersection index for the active ingredients, efficacy and elements. It was constituted for the researchers who design the Korean wild grape study to design of easier experiment. In addition, the data related to the patents for Korean wild grape which were collected from European Patent Office in response to the commercialization possibility and the system available for searching and view was established in the same viewpoint. Perl was used for the query programming and MS-SQL for database establishment and management in the designing of this database. Currently, the data is available for free use and the address is as follows. http://163.180.41.43:8011/index.html

Keywords

References

  1. Huang, K.S. and Lin, M. Oligostilbenes from the roots of Vitis amurensis. J Asian Nat Prod Res 2(1):21-28, 1999. https://doi.org/10.1080/10286029908039886
  2. Wang, J.N., Hano, Y., Nomura, T. and Chen, Y.J. Procyanidins from the seeds of Vitis amurensis. Phytochemistry 53(8):1097-1102, 2000. https://doi.org/10.1016/S0031-9422(00)00004-2
  3. Wang, J.N., Chen, Y.J., Hano, Y., Nomura, T. and Tan, R.X. Antioxidant activity of polyphenols from seeds of Vitis amurensis in vitro. Acta Pharmacol. Sin. 21(7):633-636, 2000.
  4. Kim, J.S., Ha, T.Y., Ahn, J., Kim, H.K. and Kim, S. Pterostilbene from Vitis coignetiae protect $H_{2}O_{2}$-induced inhibition of gap junctional intercellular communication in rat liver cell line. Food Chem. Toxicol. 47(2):404-409, 2009. https://doi.org/10.1016/j.fct.2008.11.038
  5. Lee, S.H., Park, S.M., Park, S.M., Park, J.H., Shin, D.Y., Kim, G.Y., Ryu, C.H., Shin, S.C., Jung, J.M., Kang, H.S., Lee, W.S. and Choi, Y.H. Induction of apoptosis in human leukemia U937 cells by anthocyanins through down-regulation of Bcl-2 and activation of caspases. Int. J. Oncol. 34(4):1077-1083, 2009.
  6. Takayama, F., Nakamoto, K., Kawasaki, H., Mankura, M., Egashira, T., Ueki, K., Hasegawa, A., Okada, S. and Mori, A. Beneficial effects of Vitis coignetiae Pulliat leaves on nonalcoholic steatohepatitis in a rat model. Acta Med. Okayama 63(2):105-111, 2009.
  7. Yabe, N., Tanaka, K. and Matsui, H. An ethanol-extract of Ampelopsis brevipedunculata (Vitaceae) berries decreases ferrous iron-stimulated hepatocyte injury in culture. J Ethnopharmacol 59(3):147-159, 1998. https://doi.org/10.1016/S0378-8741(97)00121-9
  8. Yabe, N. and Matsui, H. Ampelopsis brevipedunculata (Vitaceae) extract inhibits a progression of carbon tetrachloride-induced hepatic injury in the mice. Phytomedicine 7(6):493-498, 2000. https://doi.org/10.1016/S0944-7113(00)80035-5
  9. Wu, M.J., Yen, J.H., Wang, L. and Weng, C.Y. Antioxidant activity of Porcelainberry (Ampelopsis brevipedunculata (Maxim.) Trautv.). Am. J. Chin. Med. 32: 681-693, 2004. https://doi.org/10.1142/S0192415X04002387
  10. Wang, C.Z., Fishbein, A., Aung, H.H., Mehendale, S.R., Chang, W.T., Xie, J.T., Li, J. and Yuan, C.S. Polyphenol contents in grape-seed extracts correlate with antipica effects in cisplatin-treated rats. J Altern Complement Med 11(6):1059-1065, 2005. https://doi.org/10.1089/acm.2005.11.1059
  11. Davis, D.D. and Orendovici, T. Incidence of ozone symptoms on vegetation within a National Wildlife Refuge in New Jersey, USA. Environ. Pollut. 143(3):555-564, 2006. https://doi.org/10.1016/j.envpol.2005.10.051
  12. Huber, L., Scholz, C., Eisenbeis, G., Ruhl, E.H., Neuhauser, S. and Kirchmair, M. Field distribution of Sorosphaera viticola in commercial vineyards in Germany. FEMS Microbiol. Lett. 260(1):63-68, 2006. https://doi.org/10.1111/j.1574-6968.2006.00300.x
  13. Jenkins, P.E. and Isaacs, R. Reduced-risk insecticides for control of grape berry moth (Lepidoptera: Tortricidae) and conservation of natural enemies. J. Econ. Entomol. 100(3):855-865, 2007. https://doi.org/10.1603/0022-0493(2007)100[855:RIFCOG]2.0.CO;2
  14. Wang, R.J., Yang, B. and Fu, M.H. Quality evaluation of Flos Carthami. Zhongguo Zhong Yao Za Zhi 33(22):2642-2646, 2008.
  15. Laparra, J.M., Glahn, R.P. and Miller, D.D. Bioaccessibility of phenols in common beans ( Phaseolus vulgaris L.) and iron (Fe) availability to Caco-2 cells. J. Agric. Food Chem. 56(22):10999-11005, 2008. https://doi.org/10.1021/jf802537t
  16. Laparra, J.M., Glahn, R.P., and Miller, D.D. Assessing potential effects of inulin and probiotic bacteria on Fe availability from common beans (Phaseolus vulgaris L.) to Caco-2 cells. J. Food Sci. 74(2):H40-46, 2009. https://doi.org/10.1111/j.1750-3841.2008.01027.x
  17. Ahn, B.C., Kim, B.G., Jeon, Y.M., Lee, E.J., Lim, Y., and Ahn, J.H. Formation of flavone di-O-glucosides using a glycosyltransferase from Bacillus cereus. J. Microbiol. Biotechnol. 19(4):387-390, 2009. https://doi.org/10.4014/jmb.0802.116
  18. Takizawa, Y., Morota, T., Takeda, S., and Aburada, M. Pharmacokinetics of (-)-epicatechin-3-O-gallate, an active component of Onpi-to, in rats. Biol. Pharm. Bull. 26: 608-612, 2004.
  19. Yokozawa, T., Rhyu, D.Y., Cho, E.J., and Aoyagi, K. Protective activity of (-)-epicatechin 3-O-gallate against peroxynitrite-mediated renal damage. Free Radic. Res. 37(5):561-571, 2003. https://doi.org/10.1080/1071576031000083134
  20. Solanky, K.S., Bailey, N.J., Holmes, E., Lindon, J.C., Davis, A.L., Mulder, T.P., Van Duynhoven, J.P. and Nicholson, JK. NMR-based metabonomic studies on the biochemical effects of epicatechin in the rat. J. Agric. Food Chem. 51(14):4139-4145, 2003. https://doi.org/10.1021/jf025677f
  21. Yokozawa, T., Rhyu, D.Y., and Cho, E.J. (-)-Epicatechin 3-O-gallate ameliorates the damages related to peroxynitrite production by mechanisms distinct from those of other free radical inhibitors. J. Pharm. Pharmacol. 56(2):231-239, 2004. https://doi.org/10.1211/0022357022601
  22. Cao, S., Liu, L., Pan, S., Lu, Q. and Xu X. A comparison of two determination methods for studying degradation kinetics of the major anthocyanins from blood orange. J. Agric. Food Chem. 57(1):245-249, 2009. https://doi.org/10.1021/jf8021964
  23. 허 준 지음, 윤석희․김형준 외 옮김 대역 동의보감-東醫 寶鑑湯液編卷之二,果部, 동의보감출판사, pp 2107-2108, 2005.