Journal of Biomedical Engineering Research (대한의용생체공학회:의공학회지)

The Korean Society of Medical and Biological Engineering (대한의용생체공학회)
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Development of The Intraoperative Surgical Optical Coherence Tomography Probe

실시간 광단층 모니터링 안구 수술용 현미경 프로브 개발

  • Kim, Kyung-Un (Graduate School of Electrical Engineering and Computer science, Kyungpook National University) ;
  • Lee, Chang-Ho (Graduate School of Electrical Engineering and Computer science, Kyungpook National University) ;
  • Jeong, Hyo-Sang (Graduate School of Electrical Engineering and Computer science, Kyungpook National University) ;
  • Han, Seung-Hoon (Graduate School of Electrical Engineering and Computer science, Kyungpook National University) ;
  • Kim, Hong-Kyun (Department of ophthalmology, College of Medicine, Kyungpook National University) ;
  • Kim, Jee-Hyun (Graduate School of Electrical Engineering and Computer science, Kyungpook National University)
  • 김경운 (경북대학교 전자전기컴퓨터대학원) ;
  • 이창호 (경북대학교 전자전기컴퓨터대학원) ;
  • 정효상 (경북대학교 전자전기컴퓨터대학원) ;
  • 한승훈 (경북대학교 전자전기컴퓨터대학원) ;
  • 김홍균 (경북대학교 의과대학 안과) ;
  • 김지현 (경북대학교 전자전기컴퓨터대학원)
  • Received : 2012.01.06
  • Accepted : 2012.04.27
  • Published : 2012.06.30
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Abstract

Intraoperative surgical microscope is an essential surgical equipment. However, it has a restriction to classify the retina layers because of the contrast differences. To solve this problem, operators use surgical instrument such as an intraocular mirror. In this case, it has to amputate the patient's eye. In this study, we developed a probe the intraoperative surgical optical coherence tomography. We expect that the developed OCT probe can overcome the limit of OCT and be applied as a real-time surgical tool. In this paper, we demonstrate applicability of the probe through rabbit's experimentation.

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References

  1. D. Schultheiss and J. Denil, "History of the microscope and development of microsurgery: A revolution for reproductive tract surgery," Andrologia, vol. 34, no. 4, pp. 234-24, 2002. https://doi.org/10.1046/j.1439-0272.2002.00499.x
  2. B. Cassin and S. Solomon, Dictionary of eye terminology, Gainesville, Triad publishing company, 1990, pp. 20-25.
  3. Rodieck, R. W, The vertebrate retina: Principles of structure and function, San Francisco, W.H. Freeman, 1973, pp. 51-56.
  4. W.M. Seo, and H.K. Kim, "Early result of femtosecond laser assisted descemet's membrane stripping endothelial keratoplasty," J. Korean. Ophth. Soc., vol. 49, no. 1, pp. 40-47, 2008. https://doi.org/10.3341/jkos.2008.49.1.40
  5. K.H. Shin, D.H. Nam, and D.Y. Lee, "Comparison between retinal tear and rhegmatogenous retinal detachment as the cause of dense vitreous hemorrhage," J. Korean. Ophth. Soc., vol. 52, no. 4, pp. 448-453, 2011. https://doi.org/10.3341/jkos.2011.52.4.448
  6. R. Rabinowitz, R. Yagev, A. Shoham, and T. Lifshitz, "Comparison between clinical and ultrasound findings in patients with vitreous hemorrhage," Eye, vol. 18, no.3, pp. 253-236, 2004. https://doi.org/10.1038/sj.eye.6700632
  7. B.H. Kim, "Lightless cataract surgery using a near-infrared operating microscope," J Cataract. Refr. Surg., vol. 32, no. 10, pp. 1683-1690, 2006. https://doi.org/10.1016/j.jcrs.2006.05.024
  8. H. Ikagawa, M. Yoneda, M. Iwaki, Z. Isogai, K. Tsujii, R. Yamazaki, T. Kamiya, and Masahiro Zak, "Chemical toxicity of indocyanine green damages retinal pigment epithelium," Invest. Ophth. Vis. Sci., vol. 46, no. 7, pp. 2531-2539, 2005. https://doi.org/10.1167/iovs.04-1521
  9. G. Widmann, R. Widmann, E. Widmann, W. Jaschke, and R. Bale. "Use of a surgical navigation system for CT-guided template production," Int. J. Oral. Max. Impl., vol. 22, no.1, pp. 72-78, 2007.
  10. N. Nassif, B. Cense, B. Park, M. Pierce, S. Yun, B. Bouma, G. Tearney, T. Chen, and J. de Boer, "In vivo high-resolution video-rate spectral-domain optical coherence tomography of the human retina and optic nerve," Opt. Exp., vol. 12, no. 3, pp. 367-376, 2004. https://doi.org/10.1364/OPEX.12.000367
  11. D. Huang, E.A. Swanson, C.P. Lin, W.G. Stinson, W. Chang, M.R. Hee, T. Flotte, K. Gregory, C.A. Puliafito, and J.G. Fujimoto, "Optical coherence tomography," Science, vol. 254, no. 5035, pp. 1178-1181, 1991. https://doi.org/10.1126/science.1957169
  12. B.E. Bouma, and G.J. Tearney, Handbook of optical coherence tomography, New York, Marcel Dekker. Inc, 2002.
  13. B. Povazay, B. Hofer, C. Torti, B. Hermann, A.R. Tumlinson, M. Es- maeelpour, C.A. Egan, A.C. Bird, and W. Drexler, "Impact of enhanced resolution, speed and penetration on three-dimensional retinal optical coherence tomography," Opt. Exp., vol. 17, no. 5, pp. 4134-4150, 2009. https://doi.org/10.1364/OE.17.004134
  14. Y. Nakamura, S. Makita, M. Yamanari, M. Itoh, T. Yatagai, and Y. Yasuno, "High-speed three-dimensional human retinal imaging by line-field spectral domain optical coherence tomography," Opt. Exp., vol.15, no. 12, pp. 7103-7116, 2007. https://doi.org/10.1364/OE.15.007103
  15. J.A. Izatt, M.R. Hee, E.A. Swanson, C.P. Lin, D. Huang, J.S. Schuman, C.A. Puliafito, and J.G. Fujimoto, "Micrometerscale resolution imaging of the anterior eye in vivo with optical coherence tomography," Arch. Ophth., vol. 112, no. 12, pp. 1584-1589, 1994. https://doi.org/10.1001/archopht.1994.01090240090031
  16. C.A. Puliato, M.R. Hee, C.P. Lin, E. Reichel, J.S. Schuman, J.S. Duker, J.A. Izatt, E.A. Swanson, and J.G. Fujimoto, "Imaging of macular diseases by optical coherence tomography," Ophthalmology., vol. 102, no. 2, pp. 217-229, 1995. https://doi.org/10.1016/S0161-6420(95)31032-9
  17. G.J. Jaffe, and J. Caprioli, "Optical coherence tomography to detect and manage retinal disease and glaucoma," Am. J. Ophthalmol., vol. 137, no. 1, pp. 156-169, 2004. https://doi.org/10.1016/S0002-9394(03)00792-X
  18. M. Jeon, "Real time dual displaying handheld scanner-based compact spectral domain optical coherence tomography," Thesis ; Kyoungpook national univ., vol. 6, pp. 72-79, 2011.
  19. Y.K. Tao, J.P. Ehlers, C.A. Toth, and J.A. Izatt, "Intraoperative spectral domain optical coherence tomography for vitreoretinal surgery," Opt. Lett., vol. 35, no. 20, pp. 3315-3317, 2010. https://doi.org/10.1364/OL.35.003315