Journal of Environmental Health Sciences (한국환경보건학회지)

Korean Society of Environmental Health (한국환경보건학회)
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The Effects of Blood Lead on Blood Pressure Among Non-smokers

혈중 납이 비흡연자들의 혈압에 미치는 영향

  • Pak, Yun-Suk (The National Emergency Medical Center, National Medical Center) ;
  • Park, Sang-Sin (Department of Veterinary Integrative Biosciences, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University) ;
  • Kim, Tae-Hun (Graduate School of Public Health & Institute of Health and Environment, Seoul National University) ;
  • Lee, Sang-Yoon (Department of Preventive Medicine, Kangwon National University, Chuncheon and Occupational & Environmental Medicine, Haeundae Paik Hospital, Inje University) ;
  • Kho, Young-Lim (Department of Health, Environment and Safety, Eulji University) ;
  • Lee, Eun-Hee (Department of Visual Optics and Graduate School of Health Sciences, Far East University)
  • 박윤숙 (국립중앙의료원 중앙응급의료센터) ;
  • 박상신 ;
  • 김태훈 (서울대학교 보건대학원 및 보건환경연구소) ;
  • 이상윤 (강원대학교 예방의학교실 및 인제대학교 해운대 백병원) ;
  • 고영림 (을지대학교 보건환경안전학과) ;
  • 이은희 (극동대학교 안경광학과 및 보건과학대학원)
  • Received : 2012.06.04
  • Accepted : 2012.08.09
  • Published : 2012.08.31
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Abstract

Objective: The effect of lead on blood pressure remains controversial in spite of the numerous studies which have been conducted in the recent years. The aim of this study was to evaluate the effects of exposure to lead on blood pressure among non-smokers. Methods: In this cross sectional study, 1416 male and female non-smokers were enrolled, aged 20 years or older, from the Korean National Health and Nutrition Examination Survey 2008. Blood pressure, blood lead levels (BLLs), height, weight, and cotinine level were measured for all subjects. Results: Geometric mean BLLs of the participants was 2.20 ${\mu}g$/dl. BLLs were higher in the older, male, and lower education groups than the younger, female and higher education groups. After adjusting for age, sex, education and BMI through multiple regression analysis, a significant positive association between systolic blood pressure (p = 0.0357), diastolic blood pressure (p = 0.0111) and BLLs. Also, among the normal BMI group (18.5 kg/$m^2$ < BMI < 25 kg/$m^2$), we also found a significant positive association between diastolic blood pressure and BLLs (p = 0.0370). Conclusion: The present study showed that blood lead serves as a good predictor of blood pressure changes and that there was a statistically significant association between blood lead and blood pressure, especially diastolic blood pressure.

Keywords

References

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