Asian-Australasian Journal of Animal Sciences

  • 제25권9호
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  • Pages.1262-1268
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  • 2012
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  • 1011-2367(pISSN)
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  • 1976-5517(eISSN)
아세아태평양축산학회 (Asian Australasian Association of Animal Production Societies)
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Effect of Vitamin E Supplementation on Hematological and Plasma Biochemical Parameters during Long Term Exposure of Arsenic in Goats

  • Das, Tapan Kumar (Dairy Cattle Nutrition Division, National Dairy Research Institute) ;
  • Mani, Veena (Dairy Cattle Nutrition Division, National Dairy Research Institute) ;
  • Kaur, Harjit (Dairy Cattle Nutrition Division, National Dairy Research Institute) ;
  • Kewalramani, Neelam (Dairy Cattle Nutrition Division, National Dairy Research Institute) ;
  • Agarwal, Anjali (Dairy Cattle Nutrition Division, National Dairy Research Institute)
  • 투고 : 2012.01.05
  • 심사 : 2012.03.23
  • 발행 : 2012.09.01
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초록

The present investigation was designed to determine whether supplementation of different level of vitamin E for 12 months to arsenic exposed goats (50 ppm as sodium arsenite) affords protection against the blood hemato-biochemical parameters caused by the metalloid. A total of 24 crossbred (Alpine${\times}$Beetal) lactating goats were assigned randomly into 4 equal groups (control, $T_1$, $T_2$ and $T_3$) of 6 in each, on the basis of average body weight ($36.10{\pm}0.11$ kg) and milk yield ($1.61{\pm}0.04$ kg/d). The animals in $T_1$, $T_2$ and $T_3$ were given 50 ppm arsenic, while in $T_2$ and $T_3$, additionally; vitamin E at the rate of 100 IU and 150 IU/kg dry matter (DM) respectively was additionally supplemented for the period of 12 months. Hemoglobin (Hb), total leukocyte (TLC) and blood lymphocyte % were decreased (p<0.05) in arsenic fed groups and vitamin E supplementation in the experimental group showed a protective potential. Significant increases (p<0.05) in aspertate transaminase (AST) and alanine transaminase (ALT) activities among arsenic supplemented groups were recorded, however vitamin E supplementation at higher doses showed a protective effect (p<0.05) against AST but in the case of ALT no ameliorating effect was found in either of the doses. Plasma total protein was decreased (p>0.05) but creatinine level was periodically increased in all As supplemented groups and vitamin E supplementation did not produce any protective effect. It can be concluded that arsenic exposure resulted in varying degree of changes in hemato-biochemical parameters and activities of antioxidant enzymes in goats but concomitant treatment with Vitamin E is partially helpful in reducing the burden of arsenic induced effect.

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참고문헌

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  2. A review on hemato-biochemical, accumulation and patho-morphological responses of arsenic toxicity in ruminants pp.1556-9551, 2018, https://doi.org/10.1080/15569543.2018.1442347
  3. Sodium arsenite toxicity on hematology indices and reproductive parameters in Teddy goat bucks and their amelioration with vitamin C vol.27, pp.13, 2012, https://doi.org/10.1007/s11356-020-08049-z