Journal of Environmental Science International (한국환경과학회지)

The Korean Environmental Sciences Society (한국환경과학회)
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Anti-hyperlipidemic Effects of Cordyceps militaris Hot-Water Extract

동충하초 열수추출액의 항고지혈증 효과에 관한 연구

  • Kim, Han-Soo (Department of Food Science & Technology, Pusan National University) ;
  • Kim, Min-A (Department of Food Science & Technology, Pusan National University) ;
  • Jang, Seong-Ho (Department of Bioenviromental Energy, Pusan National University) ;
  • Lee, Won-Ki (Department of Polymer Engineering, Pukyung National University) ;
  • Ryu, Jae-Young (Division for Industrial & Environmental Research, Korea Atomic Energy Research Institute (KAERI)) ;
  • Lee, Chun-Sik (Department of Env. Eng. Gyeongnam National University of science and Technology)
  • 김한수 (부산대학교 식품공학과) ;
  • 김민아 (부산대학교 식품공학과) ;
  • 장성호 (부산대학교 바이오환경에너지학과) ;
  • 이원기 (부경대학교 고분자공학과) ;
  • 류재용 (한국원자력연구원 공업환경연구부) ;
  • 이춘식 (경남과학기술대학교 환경공학과)
  • Received : 2012.06.18
  • Accepted : 2012.07.18
  • Published : 2012.07.31
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Abstract

This study was performed to observe the effects of the feeding physiological activity substance in Cordyceps militaris hot-water extract intake on the improvement of lipid components and metabolic enzyme activities in the serum of dietary hyperlipidemic rats (SD strain, male) fed the experimental diets for 5 weeks. The concentrations of cholesterol (total cholesterol, ${\beta}$-lipoprotein, LDL-cholesterol, free cholesterol and cholesteryl ester), atherosclerotic index, triglyceride (TG), phospholipid (PL) and blood glucose in sera were remarkably lower in the Cordyceps militaris extract intake group than in the hyperlipidemic rats. In the ratio of HDL-cholesterol concentration was higher percentage in the Cordyceps militaris extract intake group than in the hyperlipidemic rats. The activities aminotransferase (AST, ALT) in sera were rather lower in the Cordyceps militaris extract administration than in the hyperlipidemic rats. From the above research, Cordyceps militaris extract were effective on the improvement of the lipid compositions in sera of dietary hyperlipidemic rats.

Keywords

References

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