Journal of Dairy Science and Biotechnology
- Volume 30 Issue 1
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- Pages.37-44
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- 2012
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- 2733-4554(pISSN)
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- 2733-4562(eISSN)
Production of Bioactive Peptides from Milk
우유에서 생리활성 펩타이드의 생산
- Seol, Kuk-Hwan (National Institute of Animal Science, RDA) ;
- Chang, Oun-Ki (National Institute of Animal Science, RDA) ;
- Kim, Min-Kyung (National Institute of Animal Science, RDA) ;
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Han, Gi-Sung
(National Institute of Animal Science, RDA) ;
- Jeong, Seok-Geun (National Institute of Animal Science, RDA) ;
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Park, Beom-Young
(National Institute of Animal Science, RDA) ;
-
Ham, Jun-Sang
(National Institute of Animal Science, RDA)
- 설국환 (농촌진흥청 국립축산과학원) ;
- 장운기 (농촌진흥청 국립축산과학원) ;
- 김민경 (농촌진흥청 국립축산과학원) ;
-
한기성
(농촌진흥청 국립축산과학원) ;
- 정석근 (농촌진흥청 국립축산과학원) ;
-
박범영
(농촌진흥청 국립축산과학원) ;
-
함준상
(농촌진흥청 국립축산과학원)
- Received : 2012.06.10
- Accepted : 2012.06.25
- Published : 2012.06.30
Abstract
Milk-derived bioactive peptides have been found to exhibit various physiological activities such as angiotensin-converting enzyme (ACE) inhibitory, antibacterial, and antioxidative effects. Bioactive peptides can be used in the formulation of functional foods, nutraceuticals, and natural drugs because of their beneficial effects. However, the degree of variability in the composition, functionality, and sensory properties of such peptides has greatly limited their use in the food industry. In this review, we discuss the main peptides obtained from milk proteins and summarize findings from previous studies on the production and biological activities of these peptides. In addition, we compare the methods used to separate and identify the structure of the bioactive peptides and highlight current investigations into engineering and implementation of technologies that would allow more efficient isolation of bioactive peptides for functional food production. To improve human health, further molecular biology studies will also be required to elucidate the complex network of interactions between food microorganisms and the digestive system.