Journal of Yeungnam Medical Science

Yeungnam University College of Medicine, Yeungnam University Institute Medical Science (영남대 의대 학술지 편집위원회)
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Huge Hepatocellular Carcinoma Abruptly Developed within 3 Months

3개월 이내에 갑자기 발생한 거대 간세포암종

  • Lee, Sang-Hyuk (Departments of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University, School of Medicine) ;
  • Kim, Byung-Ik (Departments of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University, School of Medicine) ;
  • Chon, Chang-Uk (Departments of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University, School of Medicine) ;
  • Bang, Ki-Bae (Departments of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University, School of Medicine) ;
  • Jeong, Eun-Haeng (Departments of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University, School of Medicine) ;
  • Seo, Jeong-Yeon (Departments of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University, School of Medicine) ;
  • Park, Eun-Hye (Departments of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University, School of Medicine) ;
  • Seol, Ji-Soo (Departments of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University, School of Medicine)
  • 이상혁 (성균관대학교 의과대학 강북삼성병원 내과학교실) ;
  • 김병익 (성균관대학교 의과대학 강북삼성병원 내과학교실) ;
  • 전창욱 (성균관대학교 의과대학 강북삼성병원 내과학교실) ;
  • 방기배 (성균관대학교 의과대학 강북삼성병원 내과학교실) ;
  • 정은행 (성균관대학교 의과대학 강북삼성병원 내과학교실) ;
  • 서정연 (성균관대학교 의과대학 강북삼성병원 내과학교실) ;
  • 박은혜 (성균관대학교 의과대학 강북삼성병원 내과학교실) ;
  • 설지수 (성균관대학교 의과대학 강북삼성병원 내과학교실)
  • Published : 2012.06.30
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Abstract

Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related deaths in South Korea. To decrease its mortality rate, its early detection is very important. Screening for HCC detection has been accepted as the management modality for patients with chronic liver disease. Reported herein is a case involving the marked rapid growth of HCC detected at an advanced stage in a screening test with a 3 months interval. A 49-year-old male patient with chronic hepatitis B was admitted to the hospital due to a liver mass detected on CT scan. The patient underwent a first CT scan 3 months earlier, and no tumor was detected. Follow-up CT scan was performed and showed a 9.1 cm HCC with portal vein thrombosis. Percutaneous liver biopsy was performed, and the diagnosis of hepatocellular carcinoma was confirmed. In the pertinent guidelines, the recommended screening interval for HCC is 6-12 months, but the screening interval and additional diagnostic methods should be considered due to the variation in the HCC growth rate according to the patient's clinical characteristics.

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