DOI QR코드

DOI QR Code

Multiple Large Cysts Arising from Nevus Comedonicus

  • Jeong, Hii-Sun (Department of Plastic and Reconstructive Surgery, Myongji Hospital, Kwandong University College of Medicine) ;
  • Lee, Hye-Kyung (Department of Plastic and Reconstructive Surgery, Myongji Hospital, Kwandong University College of Medicine) ;
  • Lee, Seung-Hyun (Department of Plastic and Reconstructive Surgery, Myongji Hospital, Kwandong University College of Medicine) ;
  • Kim, Hyoung-Suk (Department of Plastic and Reconstructive Surgery, Myongji Hospital, Kwandong University College of Medicine) ;
  • Yi, Sang-Yeop (Department of Pathology, Myongji Hospital, Kwandong University College of Medicine)
  • Received : 2011.08.19
  • Accepted : 2011.10.06
  • Published : 2012.01.15

Abstract

Nevus comedonicus is a type of hamartoma that arises from a developmental anomaly of the mesodermal part of the pilosebaceous gland. In most cases of nevus comedonicus, an acne-like skin condition develops. Repeated inflammation can cause a morphological change to the cyst, papule, to abscess. We experienced a case of congenital nevus comedonicus, which led to the formation of large multiple cysts. A 50-year-old man was referred with a $12.5{\times}10cm$ lobulated mass on the posterior neck and upper back. The patient had a widespread presence of nevus comedonicus in the region ranging from the right superior chest to the posterior neck. The patient had a 30-year history of six prior excisions. A magnetic resonance imaging review led to a diagnosis of nevus comedonicus. Surgical treatment consisted of excision of the mass and wide excision for the patch type of nevus comedonicus around the neck. On histopathology, multiple masses were diagnosed as typical cysts containing keratinized tissue. The diffuse comedone lesions were diagnosed as nevus comedonicus. This case shows that large, multiple cysts can occur as a long-term complication of nevus comedonicus, and also highlights the importance of radical resection to prevent its further invagination.

Keywords

References

  1. Kofmann S. Ein fall von seltener lokalisation und verbreitung von comedonen. Arch Dermatol Syphilis (Wien) 1895;32:177-8.
  2. Marcus J, Esterly NB, Bauer BS. Tissue expansion in a patient with extensive nevus comedonicus. Ann Plast Surg 1992;29:362-6. https://doi.org/10.1097/00000637-199210000-00015
  3. Beck MH, Dave VK. Extensive nevus comedonicus. Arch Dermatol 1980;116:1048-50. https://doi.org/10.1001/archderm.1980.01640330086021
  4. Kim SC, Kang WH. Nevus comedonicus associated with epidermal nevus. J Am Acad Dermatol 1989;21:1085-8. https://doi.org/10.1016/S0190-9622(89)70301-7
  5. Barsky S, Doyle JA, Winkelmann RK. Nevus comedonicus with epidermolytic hyperkeratosis: a report of four cases. Arch Dermatol 1981;117:86-8. https://doi.org/10.1001/archderm.1981.01650020028019
  6. Engber PB. The nevus comedonicus syndrome: a case report with emphasis on associated internal manifestations. Int J Dermatol 1978;17:745-9. https://doi.org/10.1111/ijd.1978.17.9.745
  7. Kim YJ, Hong CY, Lee JR. Nevus comedonicus with multiple cyst. J Korean Cleft Palate-Craniofac Assoc 2009;10:135-7.

Cited by

  1. Letter: Multiple Large Cysts Arising from Nevus Comedonicus vol.39, pp.2, 2012, https://doi.org/10.5999/aps.2012.39.2.173
  2. Reply: Multiple Large Cysts Arising from Nevus Comedonicus vol.39, pp.3, 2012, https://doi.org/10.5999/aps.2012.39.3.261
  3. Nevus Comedonicus: An Updated Review vol.3, pp.1, 2013, https://doi.org/10.1007/s13555-013-0027-9
  4. Nevus Comedonicus: A Case Series vol.32, pp.2, 2012, https://doi.org/10.1111/pde.12466
  5. Giant nevus comedonicus of the entire lower left limb protecting from the associated bullous pemphigoid: A hypothetical role of NEK9 mutation? vol.48, pp.8, 2012, https://doi.org/10.1111/1346-8138.15879