Tuberculosis and Respiratory Diseases

The Korean Academy of Tuberculosis and Respiratory Diseases (대한결핵및호흡기학회)
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A Case of Microscopic Polyangiitis Presented as Pleural Effusion

흉막삼출로 발현된 현미경적 다발혈관염 1예

  • Shin, Jin-Kyeong (Department of Internal Medicine, Bucheon St. Mary's Hospital, The Catholic University of Korea College of Medicine) ;
  • Kwon, Soon-Seog (Department of Internal Medicine, Bucheon St. Mary's Hospital, The Catholic University of Korea College of Medicine) ;
  • Park, Ki-Hoon (Department of Internal Medicine, Bucheon St. Mary's Hospital, The Catholic University of Korea College of Medicine) ;
  • Lee, Hee-Joung (Department of Pathology, Bucheon St. Mary's Hospital, The Catholic University of Korea College of Medicine) ;
  • Kim, Yong-Hyun (Department of Internal Medicine, Bucheon St. Mary's Hospital, The Catholic University of Korea College of Medicine)
  • 신진경 (가톨릭대학교 의과대학 부천성모병원 내과학교실) ;
  • 권순석 (가톨릭대학교 의과대학 부천성모병원 내과학교실) ;
  • 박기훈 (가톨릭대학교 의과대학 부천성모병원 내과학교실) ;
  • 이희정 (가톨릭대학교 의과대학 부천성모병원 병리학교실) ;
  • 김용현 (가톨릭대학교 의과대학 부천성모병원 내과학교실)
  • Received : 2011.10.07
  • Accepted : 2011.12.13
  • Published : 2012.02.29
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Abstract

Microscopic polyangiitis is a necrotizing vasculitis, characterized by inflammation of small vessels (capillaries, venules, and arterioles) with few or no immune deposits. The kidneys are the most commonly affected organs and are involved in 90% of patients, whereas pulmonary involvement occurs in a minority of cases (10% to 30%). In cases of lung disease, diffuse alveolar hemorrhage with pulmonary capillaritis is the most common manifestation. Microscopic polyangiitis is strongly associated with antineutrophil cytoplasmic autoantibody, which is a useful diagnostic serological marker. We report a case of microscopic polyangiitis presented as pleural effusion in a 67-year-old female. Pleural effusions have been reported in some cases previously, but the number of cases were small and their characteristics have not been well described. This report describes characteristic findings of pleural fluid and its histological features in a case of microscopic polyangiitis.

Keywords

References

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