개에서 Staphylococcus pseudintermedius에 의해 발생한 심내막염 증례

Staphylococcus pseudintermedius-induced Aortic and Tricuspid Bacterial Endocarditis in a Dog

  • 김준환 (전북대학교 수의과대학 및 생체안전성 연구소) ;
  • 송루희 (전북대학교 수의과대학 및 생체안전성 연구소) ;
  • 이다미 (전북대학교 수의과대학 및 생체안전성 연구소) ;
  • 이현석 (전북대학교 수의과대학 및 생체안전성 연구소) ;
  • 조호성 (전북대학교 수의과대학 및 생체안전성 연구소) ;
  • 신기욱 (전북대학교 수의과대학 및 생체안전성 연구소) ;
  • 박진호 (전북대학교 수의과대학 및 생체안전성 연구소) ;
  • 박철 (전북대학교 수의과대학 및 생체안전성 연구소)
  • Kim, Jun-Hwan (College of Veterinary Medicine and Bio-Safety Research Institute, Chonbuk National University) ;
  • Song, Ru-Hui (College of Veterinary Medicine and Bio-Safety Research Institute, Chonbuk National University) ;
  • Lee, Da-Mi (College of Veterinary Medicine and Bio-Safety Research Institute, Chonbuk National University) ;
  • Lee, Hyeon-Suk (College of Veterinary Medicine and Bio-Safety Research Institute, Chonbuk National University) ;
  • Cho, Ho-Seong (College of Veterinary Medicine and Bio-Safety Research Institute, Chonbuk National University) ;
  • Shin, Gee-Wook (College of Veterinary Medicine and Bio-Safety Research Institute, Chonbuk National University) ;
  • Park, Jin-Ho (College of Veterinary Medicine and Bio-Safety Research Institute, Chonbuk National University) ;
  • Park, Chul (College of Veterinary Medicine and Bio-Safety Research Institute, Chonbuk National University)
  • 심사 : 2012.06.14
  • 발행 : 2012.06.30

초록

14년령의 중성화한 암컷 시츄가 식욕부진, 침울, 호흡곤란으로 전북대학교 수의과대학 동물병원에 내원하였다. 2주전 유선종양 제거 수술을 받았으며 내원 당시 신체검사에서 구강 내 심한 치은염, 치태 및 치석을 관찰하였다. 청진상 좌측 심기저부에서 이완기 잡음이 들렸으며 우측 심첨부에서는 수축기성 잡음이 들렸다. 심혈관 초음파 검사 결과 삼첨판과 대동맥 판막의 변성과 함께 혈액의 역류를 관찰 할 수 있었다. 세균성 심내막염을 진단하고 그 원인체를 알기 위해 혈액배양을 실시 하였다. 혈액배양 검사 결과가 나오기 전에 항생제를 포함하여 이뇨제와 베나제프릴을 사용하였으며 환자는 잘 관리 되었다. 혈액배양 검사 결과 staphylococcus pseudintermedius가 배양 되었다. 하지만 1주일 후 환자는 급성으로 발생한 폐수종에 의해 사망하였다.

A 14-year-old spayed female, Shihtzu dog, presented with anorexia, depression and respiratory distress. She had a history of mastectomy for mammary gland tumor before 2 weeks. Severe gingivitis, dental plaque, and calculus were confirmed on physical examination. On auscultation, the dog had a diastolic and systolic murmur at the left heart base and right heart apex respectively. The dog had valvular vegetation including tricuspid and aortic valves with regurgitation on echocardiography. Blood culture was performed to confirm bacterial endocarditis and identify pathogens of bacterial endocarditis. Before the result of blood culture was confirmed, antibiotic (cefalexin, 30 mg/kg, PO, q12hr) with furosemide (2 mg/kg, PO, q12hr) and benazepril (0.25 mg/kg, PO, q12hr) were administered empirically and the patient was well controlled. Staphylococcus pseudintermedius was confirmed later. One week later, however, the patient died of acute respiratory distress caused by fulminant pulmonary edema. The owners denied necropsy of the patient.

키워드

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