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Visceral Leishmaniasis Mimicking Autoimmune Hepatitis, Primary Biliary Cirrhosis, and Systemic Lupus Erythematosus Overlap

  • Tunccan, Ozlem Guzel (Department of Clinical Microbiology and Infectious Diseases, Gazi University Hospital) ;
  • Tufan, Abdurrahman (Internal Medicine Department, Division of Rheumatology, Gazi University Hospital) ;
  • Telli, Gulcin (Department of Clinical Microbiology and Infectious Diseases, Gazi University Hospital) ;
  • Akyurek, Nalan (Department of Pathology, Gazi University Hospital) ;
  • Pamukcuoglu, Merve (Department of Hematology, Gazi University Hospital) ;
  • Yilmaz, Guldal (Department of Pathology, Gazi University Hospital) ;
  • Hizel, Kenan (Department of Clinical Microbiology and Infectious Diseases, Gazi University Hospital)
  • Received : 2012.01.30
  • Accepted : 2012.03.03
  • Published : 2012.06.15

Abstract

Visceral leishmaniasis (VL) is a life-threatening infection caused by Leishmania species. In addition to typical clinical findings as fever, hepatosplenomegaly, and cachexia, VL is associated with autoimmune phenomena. To date, VL mimicking or exacerbating various autoimmune diseases have been described, including systemic lupus erythematosus (SLE), rheumatoid arthritis, and autoimmune hepatitis (AIH). Herein, we presented a patient with VL who had overlapping clinical features with SLE, AIH, as well as antimitochondrial antibody (AMA-M2) positive primary biliary cirrhosis.

Keywords

References

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