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Immunoglobulin G4-Related Sclerosing Disease Involving the Urethra: Case Report

  • Choi, Jin Woo (Department of Radiology, Seoul National University College of Medicine, and Institute of Radiation Medicine, Seoul National University Medical Research Center) ;
  • Kim, Sang Youn (Department of Radiology, Seoul National University College of Medicine, and Institute of Radiation Medicine, Seoul National University Medical Research Center) ;
  • Moon, Kyung Chul (Department of Pathology, Seoul National University College of Medicine) ;
  • Cho, Jeong Yeon (Department of Radiology, Seoul National University College of Medicine, and Institute of Radiation Medicine, Seoul National University Medical Research Center) ;
  • Kim, Seung Hyup (Department of Radiology, Seoul National University College of Medicine, and Institute of Radiation Medicine, Seoul National University Medical Research Center)
  • Published : 2012.12.01

Abstract

Immunoglobulin G4 (IgG4)-related sclerosing disease is a systemic disease characterized by extensive IgG4-positive plasma cells and T-lymphocyte infiltration in various organs. We described the imaging findings of an IgG4-related inflammatory pseudotumor in the urethra. The urethral mass showed isoattenuation on unenhanced CT images, delayed enhancement on enhanced CT images, iso- to slight hyper-intensity on T1 and T2 weighted magnetic resonance images, diffusion restriction on diffusion weighted images, and heterogeneously low echogeneity on ultrasonography.

Keywords

References

  1. Kamisawa T, Okamoto A. IgG4-related sclerosing disease. World J Gastroenterol 2008;14:3948-3955 https://doi.org/10.3748/wjg.14.3948
  2. Kamisawa T, Nakajima H, Egawa N, Funata N, Tsuruta K, Okamoto A. IgG4-related sclerosing disease incorporating sclerosing pancreatitis, cholangitis, sialadenitis and retroperitoneal fibrosis with lymphadenopathy. Pancreatology 2006;6:132-137 https://doi.org/10.1159/000090033
  3. Leporati P, Landek-Salgado MA, Lupi I, Chiovato L, Caturegli P. IgG4-related hypophysitis: a new addition to the hypophysitis spectrum. J Clin Endocrinol Metab 2011;96:1971-1980 https://doi.org/10.1210/jc.2010-2970
  4. Higashiyama T, Nishida Y, Ugi S, Ishida M, Nishio Y, Ohji M. A case of extraocular muscle swelling due to IgG4-related sclerosing disease. Jpn J Ophthalmol 2011;55:315-317 https://doi.org/10.1007/s10384-011-0014-6
  5. Katsura M, Morita A, Horiuchi H, Ohtomo K, Machida T. IgG4-related inflammatory pseudotumor of the trigeminal nerve: another component of IgG4-related sclerosing disease? AJNR Am J Neuroradiol 2011;32:E150-E152 https://doi.org/10.3174/ajnr.A2256
  6. Park SB, Cho KS, Kim JK, Lee JH, Jeong AK, Kwon WJ, et al. Inflammatory pseudotumor (myoblastic tumor) of the genitourinary tract. AJR Am J Roentgenol 2008;191:1255-1262 https://doi.org/10.2214/AJR.07.3663
  7. Zen Y, Fujii T, Sato Y, Masuda S, Nakanuma Y. Pathological classification of hepatic inflammatory pseudotumor with respect to IgG4-related disease. Mod Pathol 2007;20:884-894 https://doi.org/10.1038/modpathol.3800836
  8. Yamamoto H, Yamaguchi H, Aishima S, Oda Y, Kohashi K, Oshiro Y, et al. Inflammatory myofibroblastic tumor versus IgG4-related sclerosing disease and inflammatory pseudotumor: a comparative clinicopathologic study. Am J Surg Pathol 2009;33:1330-1340 https://doi.org/10.1097/PAS.0b013e3181a5a207
  9. Narla LD, Newman B, Spottswood SS, Narla S, Kolli R. Inflammatory pseudotumor. Radiographics 2003;23:719-729 https://doi.org/10.1148/rg.233025073
  10. Harr DL, Quencer RM, Abrams GW. Computed tomography and ultrasound in the evaluation of orbital infection and pseudotumor. Radiology 1982;142:395-401 https://doi.org/10.1148/radiology.142.2.7054828
  11. Andrich DE, Rickards D, Landon DN, Fowler CJ, Mundy AR. Structural assessment of the urethral sphincter in women with urinary retention. J Urol 2005;173:1246-1251 https://doi.org/10.1097/01.ju.0000156833.84907.3d

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