Korean Journal of Radiology

  • 제13권6호
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  • Pages.760-770
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  • 2012
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  • 1229-6929(pISSN)
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  • 2005-8330(eISSN)
대한영상의학회 (The Korean Society of Radiology)
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Opportunities for 2-[$^{18}F$] Fluoro-2-Deoxy-D-Glucose PET/CT in Cervical-Vaginal Neuroendocrine Carcinoma: Case Series and Literature Review

  • Lin, Yin (Department of Nuclear Medicine, Taichung Veterans General Hospital) ;
  • Lin, Wan Y. (Department of Nuclear Medicine, Taichung Veterans General Hospital) ;
  • Liang, Ji A. (Graduate Institute of Clinical Medicine Science and School of Medicine, College of Medicine, China Medical University) ;
  • Lu, Yu Y. (Department of Nuclear Medicine, Taichung Veterans General Hospital) ;
  • Wang, Hsin Y. (Department of Nuclear Medicine, Taichung Veterans General Hospital) ;
  • Tsai, Shih C. (Department of Nuclear Medicine, Taichung Veterans General Hospital) ;
  • Kao, Chia H. (Graduate Institute of Clinical Medicine Science and School of Medicine, College of Medicine, China Medical University)
  • 발행 : 2012.12.01
⟨ 이전 논문 다음 논문 ⟩

초록

Objective: Neuroendocrine cervical carcinoma is a rare subtype of cervical cancer. These tumors exhibit an aggressive behavior with early regional lymph node and distant metastases. The purpose of our study was to describe five cases of neuroendocrine cervical-vaginal carcinoma and to discuss the potential of the 2-[$^{18}F$] fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography ($^{18}F$-FDG PET/CT) scan for the detection of this rare malignancy. Materials and Methods: Five cases of cervical-vaginal neuroendocrine tumor were retrospectively collected, during a two year (from September 2009 to August 2011) period in our hospital. The clinical staging distributions were International Federation of Gynecology and Obstetrics (FIGO) stage IB2 (1 of 5), stage IIA (3 of 5) and stage IVA (1 of 5). Results: Two cases (cases 1 and 4) were restaged after $^{18}F$-FDG PET/CT scan in the initial staging process. Post-treatment $^{18}F$-FDG PET/CT scans, in three patients, revealed positive findings for tumor recurrence or lymph node metastases. Two patients (cases 2 and 3) died of tumor within two years. Conclusion: $^{18}F$-FDG PET/CT scan is a useful tool in cervical-vaginal neuroendocrine tumor. In its initial staging, the $^{18}F$-FDG PET/CT scan may help assess the possible nodal involvement or early hematogeneous spreading. We can also use the $^{18}F$-FDG PET/CT to detect local recurrence and to evaluate the treatment response after clinical manipulation.

키워드

참고문헌

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피인용 문헌

  1. 18F-FDG PET in small-cell cervical cancer: a prospective study with long-term follow-up vol.43, pp.4, 2012, https://doi.org/10.1007/s00259-015-3229-9
  2. Imaging and staging of neuroendocrine cervical cancer vol.43, pp.12, 2012, https://doi.org/10.1007/s00261-018-1667-0
  3. Neuroendocrine carcinoma of the cervix: a systematic review of the literature vol.18, pp.None, 2012, https://doi.org/10.1186/s12885-018-4447-x
  4. Clinical and MRI Characteristics of Uterine Cervical Adenocarcinoma: Its Variants and Mimics vol.20, pp.3, 2012, https://doi.org/10.3348/kjr.2018.0458
  5. 18F-FDG PET/computed tomography scan in patients with suspicion of recurrent neuroendocrine carcinoma of the cervix vol.42, pp.10, 2012, https://doi.org/10.1097/mnm.0000000000001432