Annals of Laboratory Medicine

Korean Society for Laboratory Medicine (대한진단검사의학회)
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Antifungal Susceptibility to Amphotericin B, Fluconazole, Voriconazole, and Flucytosine in Candida Bloodstream Isolates from 15 Tertiary Hospitals in Korea

  • Jung, Sook-In (Department of Internal Medicine, Chonnam National University Medical School) ;
  • Shin, Jong Hee (Department of Laboratory Medicine, Chonnam National University Medical School) ;
  • Choi, Hyun-Jung (Department of Laboratory Medicine, Chonnam National University Medical School) ;
  • Ju, Min-Young (Department of Laboratory Medicine, Chonnam National University Medical School) ;
  • Kim, Soo-Hyun (Department of Laboratory Medicine, Chonnam National University Medical School) ;
  • Lee, Wee Gyo (Department of Laboratory Medicine, Ajou University College of Medicine) ;
  • Park, Yeon-Joon (Department of Laboratory Medicine, The Catholic University of Korea College of Medicine) ;
  • Lee, Kyungwon (Department of Laboratory Medicine and Research Institute of Bacterial Resistance, Yonsei University College of Medicine) ;
  • Korean Study Group for Candidemia, Korean Study Group for Candidemia (Korean Study Group for Candidemia)
  • Published : 2012.11.01
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Abstract

The in vitro antifungal susceptibility of 636 Candida bloodstream isolates collected from 15 tertiary hospitals in Korea was determined using the Vitek-2 yeast susceptibility system (bioM$\acute{e}$rieux, France). Overall susceptibility rates were 98.1%, 95.9%, 99.1%, and 97.3% for amphotericin B, fluconazole, voriconazole, and flucytosine, respectively. The results show that the rates of resistance to 4 antifungal drugs remain low among Candida bloodstream isolates in Korea.

Keywords

References

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  2. Pfaller MA, Diekema DJ, Procop GW, Rinaldi MG. Multicenter comparison of the VITEK 2 yeast susceptibility test with the CLSI broth microdilution reference method for testing fluconazole against Candida spp. J Clin Microbiol 2007;45:796-802. https://doi.org/10.1128/JCM.01986-06
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