The Korean Journal of Medicine

The Korean Association of Internal Medicine (대한내과학회)
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Platelet Dysfunction in a Patient with Multiple Myeloma: A Case Report with a Literature Review

다발성 골수종 환자에서 발생한 혈소판 기능 장애

  • Na, Soo-Young (Department of Internal Medicine, Asan Medical Center, University of Ulsan Collage of Medicine) ;
  • Park, Jin Wook (Department of Internal Medicine, Asan Medical Center, University of Ulsan Collage of Medicine) ;
  • Choi, Jun Seok (Department of Internal Medicine, Asan Medical Center, University of Ulsan Collage of Medicine) ;
  • Lee, Dae Ho (Department of Internal Medicine, Asan Medical Center, University of Ulsan Collage of Medicine) ;
  • Chi, Hyun-Sook (Department of Laboratory Medicine, Asan Medical Center, University of Ulsan Collage of Medicine) ;
  • Lee, Jung-Shin (Department of Internal Medicine, Asan Medical Center, University of Ulsan Collage of Medicine) ;
  • Suh, Cheolwon (Department of Internal Medicine, Asan Medical Center, University of Ulsan Collage of Medicine)
  • 나수영 (울산대학교 의과대학 서울아산병원 내과) ;
  • 박진욱 (울산대학교 의과대학 서울아산병원 내과) ;
  • 최준석 (울산대학교 의과대학 서울아산병원 내과) ;
  • 이대호 (울산대학교 의과대학 서울아산병원 내과) ;
  • 지현숙 (울산대학교 의과대학 서울아산병원 진단검사의학과) ;
  • 이정신 (울산대학교 의과대학 서울아산병원 내과) ;
  • 서철원 (울산대학교 의과대학 서울아산병원 내과)
  • Published : 2012.12.01
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Abstract

Multiple myeloma is a monoclonal plasma cell proliferation disorder with various symptoms and signs caused by paraproteinemias. Among these signs, a bleeding tendency is one of the major fatal causes. However, significant severe bleeding is rare in most cases. In this study, we report a case of multiple myeloma in a patient who had a severe recurrent bleeding tendency due to platelet dysfunction caused by paraproteins. After being treated with therapeutic plasma exchange and chemotherapy, the patient's monoclonal protein level decreased and the bleeding stopped.

Keywords

References

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