The Korean Journal of Medicine

The Korean Association of Internal Medicine (대한내과학회)
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Granular Cell Tumor Originating from Gallbladder

담낭에서 유례한 과립막 세포종 1예

  • Kim, Dong Kyu (Department of Internal Medicine, Gil Hospital, Gachon University of Medicine and Science) ;
  • Jung, Young Kul (Department of Internal Medicine, Gil Hospital, Gachon University of Medicine and Science) ;
  • Chung, Dong Hae (Department of Pathology, Gil Hospital, Gachon University of Medicine and Science) ;
  • Kim, Hyung Sik (Department of Radiology, Gil Hospital, Gachon University of Medicine and Science) ;
  • Kwon, Oh Sang (Department of Internal Medicine, Gil Hospital, Gachon University of Medicine and Science) ;
  • Kim, Yun Soo (Department of Internal Medicine, Gil Hospital, Gachon University of Medicine and Science) ;
  • Kim, Ju Hyun (Department of Internal Medicine, Gil Hospital, Gachon University of Medicine and Science)
  • 김동규 (가천의과학대학교 길병원 소화기내과) ;
  • 정영걸 (가천의과학대학교 길병원 소화기내과) ;
  • 정동해 (가천의과학대학교 길병원 병리과) ;
  • 김형식 (가천의과학대학교 길병원 영상의학과) ;
  • 권오상 (가천의과학대학교 길병원 소화기내과) ;
  • 김연수 (가천의과학대학교 길병원 소화기내과) ;
  • 김주현 (가천의과학대학교 길병원 소화기내과)
  • Published : 2012.11.01
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Abstract

Granular cell tumors are rare benign tumors that arise from Schwann cells. They are especially rare in the gallbladder; indeed, only four cases have been reported in the English-language literature. This paper reports a granular cell tumor in the gallbladder and is the first such report in a Korean woman. She was admitted to the hospital with jaundice and fever and was diagnosed with acute hepatitis A. While hospitalized, a well-demarcated round mass was incidentally found in her gallbladder. The acute hepatitis A improved with conservative care, but the mass did not change in size after 4 months. The tumor was resected with the gallbladder during laparoscopic surgery, and was found to be a granular cell tumor. The tumor was composed of sheets or irregular fascicles of large polygonal or spindle cells with plump eosinophilic granular cytoplasm that was immunohistochemically positive for S-100 and neuron-specific enolase and negative for neurofilament.

Keywords

References

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