Parasites, Hosts and Diseases

The Korea Society for Parasitology and Tropical Medicine (대한기생충학·열대의학회)
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Transmission of $Toxocara$ $canis$ via Ingestion of Raw Cow Liver: A Cross-Sectional Study in Healthy Adults

  • Choi, Dong-Il (Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Lim, Jae-Hoon (Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Choi, Dong-Chull (Department of Internal Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Lee, Kyung-Soo (Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Paik, Seung-Woon (Department of Internal Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Kim, Sun-Hee (Department of Laboratory Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Choi, Yoon-Ho (Center for Health Promotion, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Huh, Sun (Department of Parasitology, College of Medicine, Hallym University)
  • Received : 2011.08.08
  • Accepted : 2011.11.16
  • Published : 2012.03.30
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Abstract

The aim of this study is to ascertain the relationship between ingestion of raw cow liver and $Toxocara$ $canis$ infection. A total of 150 apparently healthy adults were divided into 2 groups; 1 group consisted of 86 adults with positive results of Toxocara ELISA, and the other group of 64 adults with negative results. One researcher collected the history of ingestion of raw cow liver within 1 year and recent history of keeping dogs. Among 86 seropositive adults for $T.$ $canis$, 68 (79.1%) had a recent history of ingestion of raw cow liver. Multivariate statistical analysis showed that a recent ingestion of raw cow liver and keeping dogs were related to an increased risk of toxocariasis (odds ratios, 4.4 and 3.7; and 95% confidence intervals, 1.9-10.2 and 1.2-11.6, respectively). A recent history of ingestion of raw cow liver and keeping dogs was significantly associated with toxocariasis.

Keywords

References

  1. Orihel TC, Ash LR. Parasites in Human Tissues. Chicago, USA. American Society of Clinical Pathologists Press, 1995.
  2. Beaver PC. The nature of visceral larva migrans. J Parasitol 1969; 55: 3-12.
  3. Bever PC. Larva migrans. Exp Parasitol 1956; 5: 587-621. https://doi.org/10.1016/0014-4894(56)90032-7
  4. Glickman LT, Schantz PM. Epidemiology and pathogenesis of zoonotic toxocariasis. Epidemiol Rev 1981; 3: 230-250. https://doi.org/10.1093/oxfordjournals.epirev.a036235
  5. Pahari TK, Sasmal NK. Experimental infection of Japanese quail with Toxocara canis larvae through earthworms. Vet Parasitol 1991; 39: 337-340. https://doi.org/10.1016/0304-4017(91)90051-V
  6. Pahari TK, Sasmal NK. Experimental infection of mice with Toxocara canis larvae obtained from Japanese quails. Int J Parasitol 1990; 20: 263-264. https://doi.org/10.1016/0020-7519(90)90110-9
  7. Taira K, Saeed I, Permin A, Kapel CM. Zoonotic risk of Toxocara canis infection through consumption of pig or poultry viscera. Vet Parasitol 2004; 121: 115-124. https://doi.org/10.1016/j.vetpar.2004.01.018
  8. Lee KT, Min HK, Chung PR, Chang JK. Studies on the inducing possibility of human visceral larva migrans associated with eating habit of raw liver of domestic animals. Korean J Parasitol 1976; 14: 51-60. https://doi.org/10.3347/kjp.1976.14.1.51
  9. Chang S, Lim JH, Choi D, Park CK, Kwon NH, Cho SY, Choi DC. Hepatic visceral larva migrans of Toxocara canis: CT and sonographic findings. AJR Am J Roentgenol 2006; 187: W622-W629. https://doi.org/10.2214/AJR.05.1416
  10. Kwon NH, Oh MJ, Lee SP, Lee BJ, Choi DC. The prevalence and diagnostic value of toxocariasis in unknown eosinophilia. Ann Hematol 2006; 85: 233-238. https://doi.org/10.1007/s00277-005-0069-x
  11. Fitzgerald PR, Mansfield ME. Visceral larva migrans (Toxocara canis) in calves. Am J Vet Res 1970; 31: 561-565.
  12. Fan CK, Lan HS, Hung CC, Chung WC, Liao CW, Du WY, Su KE. Seroepidemiology of Toxocara canis infection among mountain aboriginal adults in Taiwan. Am J Trop Med Hyg 2004; 71: 216-221.
  13. Salem G, Schantz P. Toxocaral visceral larva migrans after ingestion of raw lamb liver. Clin Infect Dis 1992; 15: 743-744. https://doi.org/10.1093/clind/15.4.743
  14. Nagakura K, Tachibana H, Kaneda Y, Kato Y. Toxocariasis possibly caused by ingesting raw chicken. J Infect Dis 1989; 160: 735-736. https://doi.org/10.1093/infdis/160.4.735
  15. Morimatsu Y, Akao N, Akiyoshi H, Kawazu T, Okabe Y, Aizawa H. A familial case of visceral larva migrans after ingestion of raw chicken livers: appearance of specific antibody in bronchoalveolar lavage fluid of the patients. Am J Trop Med Hyg 2006; 75: 303-306.
  16. Choi D, Lim JH, Choi DC, Paik SW, Kim SH, Huh S. Toxocariasis and ingestion of raw cow liver in patients with eosinophilia. Korean J Parasitol 2008; 46: 139-143. https://doi.org/10.3347/kjp.2008.46.3.139
  17. Jacquier P, Gottstein B, Stingelin Y, Eckert J. Immunodiagnosis of toxocarosis in humans: evaluation of a new enzyme-linked immunosorbent assay kit. J Clin Microbiol 1991; 29: 1831-1835.
  18. Schantz PM. Toxocara larva migrans now. Am J Trop Med Hyg 1989; 41: S21-34. https://doi.org/10.4269/ajtmh.1989.41.21
  19. Sturchler D, Weiss N, Gassner M. Transmission of toxocariasis. J Infect Dis 1990; 162: 571.
  20. Dubey JP. Migration of Toxocara cati larvae in mice. Trop Geogr Med 1968; 20: 172-176.
  21. Luo ZJ, Wang GX, Yang CI, Luo CH, Cheng SW, Liao L. Detection of circulating antigens and antibodies in Toxocara canis infection among children in Chengdu, China. J Parasitol 1999; 85: 252-256. https://doi.org/10.2307/3285628
  22. Hakim SL, Mak JW, Lam PL. ELISA seropositivity for Toxocara canis antibodies in Malaysia, 1989-1991. Med J Malaysia 1993; 48: 303-307.
  23. Sadjjadi SM, Khosravi M, Mehrabani D, Orya A. Seroprevalence of toxocara infection in school children in Shiraz, southern Iran. J Trop Pediatr 2000; 46: 327-330. https://doi.org/10.1093/tropej/46.6.327
  24. Uhlíkova M, Hübner J. Seroprevalence of Toxocara canis infection in Czech Republic. Cent Eur J Public Health 1998; 6: 195-198.
  25. Pelloux H, Faure O. Toxocariasis in adults. Rev Med Interne 2004; 25: 201-206. https://doi.org/10.1016/S0248-8663(03)00258-3
  26. Speiser F, Gottstein B. A collaborative study on larval excretory/secretory antigens of Toxocara canis for the immunodiagnosis of human toxocariasis with ELISA. Acta Trop 1984; 41: 361-372.
  27. Park HY, Lee SU, Huh S, Kong Y, Magnaval JF. A seroepidemiological survey for toxocariasis in apparently healthy residents in Gangwon-do, Korea. Korean J Parasitol 2002; 40: 113-117. https://doi.org/10.3347/kjp.2002.40.3.113
  28. Uga S, Ono K, Kataoka N, Hasan H. Seroepidemiology of five major zoonotic parasite infections in inhabitants of Sidoarjo, East Java, Indonesia. Southeast Asian J Trop Med Public Health 1996; 27: 556-561.
  29. Rai SK, Uga S, Ono K, Nakanishi M, Shrestha HG, Matsumura T. Seroepidemiological study of Toxocara infection in Nepal. Southeast Asian J Trop Med Public Health 1996; 27: 286-290.

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