참고문헌
- J. M. Kyriakis and J. Avruch, "Pp54 microtubuleassociated protein 2 kinase", J. Biol. Chem., Vol. 265, pp. 17355-17363, 1990.
- M. Hibi, A. Lin, T. Smeal, A. Minden, and M. Karin, "Identification of an oncoprotein and UVresponsive protein kinase that binds and potentiates the c-Jun activation domain", Genes and Development., Vol. 7, pp. 2135-2148, 1993. https://doi.org/10.1101/gad.7.11.2135
- V. Adler, A. Polotskaya, F. Wagner, and A. S. Kraft, "Affinity-purified c-Jun amino-terminal protein kinase requires serine/threonine phosphorylation for activity", J. Biol. Chem., Vol. 267, pp. 17001-17005, 1992.
- R. J. Davis, "Signal transduction by the JNK group of MAP kinases", Cell., Vol. 103, pp. 239-252, 2000. https://doi.org/10.1016/S0092-8674(00)00116-1
- A. M. Bode and Z. Dong, "The functional contrariety of JNK", Molecular carcinogenesis., Vol. 46, pp. 591-598, 2007. https://doi.org/10.1002/mc.20348
- S. Gupta, T. Barrett, A. J. Whitmarsh, J. Cavanagh, H.K. Sluss, B. Derijard, and R. J. Davis, "Selective interaction of JNK protein kinase isoforms with transcription factors", EMBO J., Vol. 15, No. 11, pp. 2760-2770.
- J. H. Martin, A. A. Mohit, and C. A. Miller, "Developmental expression in the mouse nervous system of the p493F12 SAP kinase", Mol. Brain Res., Vol. 35, pp. 47-57, 1996. https://doi.org/10.1016/0169-328X(95)00181-Q
- C. Dong, D. D. Yang, M. Wysk, A. J. Whitmarsh, R. J. Davis, and R. A. Flavell, "Defective T cell differentiation in the absence of Jnk1", Science., Vol. 282, pp. 2092-2095, 1998. https://doi.org/10.1126/science.282.5396.2092
- J. M. Kyriakis and J. Avruch, "Mammalian mitogen- activated protein kinase signal transduction pathways activated by stress and inflammation", Physiol. Rev., Vol. 81, pp. 807-869, 2001.
- G.Y. Zhang, and Q. G. Zhang, "Agents targeting c-Jun N-terminal kinase pathway as potential neuroprotectants", Expert Opin. Invest. Drugs., Vol. 14, pp. 1373-1383, 2005. https://doi.org/10.1517/13543784.14.11.1373
- J. M. A. Siddiqui and P. A. Reddy, "Small Molecule JNK (c-Jun N-Terminal Kinase) Inhibitors", J. Med. Chem., Vol. 53, pp. 3005-3012, 2010. https://doi.org/10.1021/jm9003279
- R. Jiang, D. Duckett, W. Chen, J. Habel, Y. Y. Ling, P. L. Grassob, and T. M. Kamenecka, "3,5-Disubstituted quinolines as novel c-Jun N-terminal kinase inhibitors", Bioorganic and Medicinal Chemistry Letters., Vol. 17, pp. 6378-6382, 2007. https://doi.org/10.1016/j.bmcl.2007.08.054
- G. Klebe, U. Abraham, and T. Mietzner, "Molecular similarity indices in a comparative analysis (CoMSIA) of drug molecules to correlate and predict their biological activity", J. Med. Chem., Vol. 37, pp. 4130-4146, 1994. https://doi.org/10.1021/jm00050a010
- Sybyl 8.1, Tripos Inc., St. Louis, MO 63144, USA.
- S. J. Cho and A. Tropsha, "Cross-validated R2- guided region selection for comparative molecular field analysis: A simple method to achieve consistent results", J. Med. Chem., Vol. 38, pp.1060-1066, 1995. https://doi.org/10.1021/jm00007a003
- S. Wold, M. Sjostrom, and L. Eriksson, "PLSregression: a basic tool of chemometrics", Chemometrics and intell. lab. Sy., Vol. 58, pp. 109-130, 2001. https://doi.org/10.1016/S0169-7439(01)00155-1