Risk Factors Associated with Cataract by in Middle-aged and Older Korean Adults

한국인의 장년층과 노년층의 백내장 위험 요인

  • 김효진 (백석대학교 보건학부 안경광학과)
  • Received : 2012.10.15
  • Accepted : 2012.12.15
  • Published : 2012.12.31

Abstract

Purpose: This study was found the risk factors of cataract by gender in elder and older Korean adults. Methods: We investigated the data for 5,024 (men 2,163 people, women 2,861 people) people, aged 40-95 years, from the Korean National Health and Nutrition Examination Survey. We divided into two groups (group 1: 40-64 years, group 2: 65-94 years). We divided into two groups (group 1: 40-64 years, group 2: 65-94 years). Cataract was decided in case of at least one eye with lens opacity. We presented significant odds ratio (OR) increase of cataract according to the obesity and socioeconomic information including house income and education level after adjusting for diabetes, hypertension, high triglyceride, outside active, smoking and drinking habits in two groups with distinction of sex. Results: House income (or education) was strongly related to the prevalence of agerelated cataract in all groups. In models adjusting for all other related factors, cataract patients with lower income and education had a higher prevalence of cataract (group1: OR, 1.84[1.17-2.91], OR, 3.00[1.90-4.74], group 2: OR, 3.47[2.53-4.74], OR, 7.44[5.41-10.23] for men. In comparison, for women, cataract patients with lower income, lower education and obesity had a higher prevalence of cataract (group1: OR, 1.72[1.14-2.60], OR, 4.48[2.72-7.38], OR, 1.40[1.10-1.82], group 2: OR, 2.32[1.70-3.16], OR, 29.99[20.31-44.28], OR, 1.27[1.04-1.54]). Conclusions: Factors of low socioeconomic status were associated with age-related cataract in Korean. Obesity-cataract association was stronger in women.

목적: 한국인을 대상으로 장년층과 노년층에서 남녀 각각 백내장 발병의 관련 요인을 알아보고자 하였다. 방법: 국민건강영양조사 자료를 이용하여 40-95세까지 총 5,024명 (남자 2,163명, 여자 2,861명)을 대상으로 하였고, 남녀각각 연령에 따라 두 그룹으로 분류하였다(그룹 1: 40-64세, 그룹 2: 65-94세). 백내장은 적어도 한 눈에 수정체의 혼탁이 발견된 경우로 정의하였다. 남녀 각각 두 연령 그룹에서 당뇨, 고혈압, 고중성지방혈증, 실외 활동, 흡연과 음주 습관을 보정한 후에 비만과 사회경제적 요인으로 가구 소득수준과 최종학력을 기준으로 교육수준이 백내장의 발병에 영향을 미치는지 비차비 값을 구하였다. 결과: 소득수준과 교육수준은 남녀 모든 연령 그룹에서 백내장 발병과 강한 관련이 있었다. 모든 다른 요인들을 보정한 후에 최종 다중분석 모델에서 남자의 경우는 저 소득(그룹 1:OR, 1.84[1.17-2.91], 그룹 2: 3.47[2.53-4.74]), 저 학력(그룹 1: OR, 3.00[1.90-4.74], 그룹 2: 7.44[5.41-10.23])과 실외 활동시간(그룹 2: OR, 1.26[1.06-1.49]이 백내장의 발병 위험을 높였다. 여자의 경우에는 저 소득(그룹 1: OR,1.72[1.14-2.60], 그룹 2: 2.32[1.70-3.16]), 저 학력(그룹 1: OR, 4.48[2.72-7.38], 그룹 2: 29.99[20.31-44.28])과 비만(그룹 1: OR, 1.40[1.10-1.82], 그룹 2: 1.27[1.04-1.54])이 유의한 위험 요인이었다. 결론: 한국 성인 남녀에서 낮은 사회경제적 상태는 백내장의 위험 요인이었고, 특히 여성의 경우는 비만도 백내장과 관련이 있었다.

Keywords

References

  1. Statistics Korea. Korean statistical information service, 2010. http://kosis.kr/abroad/abroad_01List.jsp(1 April 2012).
  2. Lee HK, Lee SH, Lee EW. Characteristics and factors related to problem drinking of the elderly in Korea. J of the Korea Society of Health Statistics. 2012;37(1):64-75.
  3. Kim O, Hwang JW, Kim KR, Kang JS. The experiences of daily life among elderly women with cataracts. Qualitative Research. 2008;9(2):129-141.
  4. Resnikoff S, Pascolini D, Etya'ale D, Kocur I, Pararajasegaram R, Pokharel GP, et al. Global data on visual impairment in the year 2002. Bull World Health Organ. 2004; 82(11):844-851.
  5. Yoon KC, Mun GH, Kim SD, Kim SH, Kim CY, Park KH, et al. Prevalence of eye disease in south korea: data from the korea national health and nutrition examination survey 2008-2009. Korean J Ophthalmol. 2011;25(6):421- 433. https://doi.org/10.3341/kjo.2011.25.6.421
  6. Klein BE, Klein RE, Lee KE. Incident cataract after a five-year interval and lifestyle factors: the Beaver Dam eye study. Ophthalmic Epidemiol. 1999; 6(4):247-255. https://doi.org/10.1076/opep.6.4.247.4190
  7. Navarro Esteban JJ, Gutirrez Leiva JA, Valero Caracena N, Buenda Bermejo J, Calle Purn ME, Martnez Vizcano VJ. Prevalence and risk factors of lens opacities in the elderly in Cuenca, Spain. Eur J Ophthalmol. 2007;17(1): 29-37.
  8. Raju P, George R, Ve Ramesh S, Arvind H, Baskaran M, Vijaya L. Influence of tobacco use on cataract development. Br J Ophthalmol. 2006;90(11):1374-1377. https://doi.org/10.1136/bjo.2006.097295
  9. Krishnaiah S, Vilas K, Shamanna BR, Rao GN, Thomas R, Balasubramanian D. Smoking and its association with cataract: results of the Andhra Pradesh eye disease study from India. Invest Ophthalmol Vis Sci. 2005;46(1):58-65. https://doi.org/10.1167/iovs.04-0089
  10. Klein BE, Klein R, Lee KE, Meuer SM. Socioeconomic and lifestyle factors and the 10-year incidence of agerelated cataracts. Am J Ophthalmol. 2003;136(3):506-512. https://doi.org/10.1016/S0002-9394(03)00290-3
  11. Foster PJ, Wong TY, Machin D, Johnson GJ, Seah SKL. Risk factors for nuclear, cortical and posterior subcapsular cataracts in the Chinese population of Singapore: the Tanjong Pagar Survey. Br J Ophthalmol. 2003;87(9):1112-1120. https://doi.org/10.1136/bjo.87.9.1112
  12. Leske MC, Wu SY, Hennis A, Connell AM, Hyman L, Schachat A. Diabetes, hypertension, and central obesity as cataract risk factors in a black population. The Barbados Eye Study. Ophthalmology. 1999;106(1):35-41. https://doi.org/10.1016/S0161-6420(99)90003-9
  13. Younan C, Mitchell P, Cumming R, Rochtchina E, Panchapakesan J, Tumuluri K. Cardiovascular disease, vascular risk factors and the incidence of cataract and cataract surgery: the Blue Mountains Eye Study. Ophthalmic Epidemiol. 2003;10(4):227-240. https://doi.org/10.1076/opep.10.4.227.15905
  14. Leske MC, Wu SY, Hennis A, Connell AM, Hyman L, Schachat A. Diabetes, hypertension, and central obesity as cataract risk factors in a black population. The Barbados Eye Study. Ophthalmology. 1999;106(1):35-41. https://doi.org/10.1016/S0161-6420(99)90003-9
  15. Schaumberg DA, Glynn RJ, Christen WG, Hankinson SE, Hennekens CH. Relations of body fat distribution and height with cataract in men. Am J Clin Nutr. 2000; 72(6): 1495-1502.
  16. Park SS, Lee EH. Relations of cataract to metabolic syndrome and its components-based on the KNHANES 2005, 2007. J Korean Oph Opt Soc. 2009;14(3):103-108.
  17. West SK, Munoz B, Schein OD, Duncan DD, Rubin GS. Racial differences in lens opacities: the Salisbury Eye Evaluation (SEE) project. Am J Epidemiol. 1998;148(11): 1033-1039. https://doi.org/10.1093/oxfordjournals.aje.a009579
  18. Javitt JC, Wang F, West SK. Blindness due to cataract: epidemiology and prevention. Annu Rev Public Health. 1996;17(1):159-177. https://doi.org/10.1146/annurev.pu.17.050196.001111
  19. Athanasiov PA, Casson RJ, Sullivan T, Newland HS, Shein WK, Muecke JS, Selva D, Aung T. Cataract in rural Myanmar: prevalence and risk factors from the Meiktila Eye Study. Br J Ophthalmol. 2008;92(9):1169-1174. https://doi.org/10.1136/bjo.2008.139725
  20. Park JH, Kim HJ, Ye KH. Study on relationship between eye health and household income of the elderly. J Korean Oph Opt Soc. 2011;16(2):209-217.
  21. Park JH. The relationship between prevalence of the cataract with smoking and socioeconomic factors in korean adults. J Korean Vis Sci. 2011;13(3):197-203.
  22. Park SS, Lee EH. Relations of cataract to metabolic syndrome and its components-based on the KNHANES 2005, 2007. J Korean Oph Opt Soc. 2009;14(3):103-108.
  23. Meigs JB. Definitions and mechanisms of the metabolic syndrome. Current opinion in endocrinology & Diabetes. 2006;13(2):103-110.
  24. Woo HB, Yoon IJ. Differences in the health status of the Korea elderly by socio - demographic factors. Health and Social Science. 2001;9(4):67-106.
  25. Kim MY, Oh JK, Lim MK, Yun EH, Kang YH. The association of socioeconomic and psychosocial factors with obesity in a rural community. The Korean Journal of Obesity. 2012;21(1):18-28. https://doi.org/10.7570/kjo.2012.21.1.18
  26. Zigman S, Datiles M, Torczynski E. Sunlight and human cataracts. Invest Ophthalmol Vis Sci. 1979;18(5):462-467.
  27. Brilliant LB, Grasset NC, Pokhrel RP, Kolstad A, Lepkowski JM, Brilliant GE, et al. Associations among cataract prevalence, sunlight hours, and altitude in the Himalayas. American Journal of Epidemiology. 1983;118(2):250-264.
  28. Cruickshanks KJ, Klein BE, Klein R. Ultraviolet light exposure and lens opacities: the Beaver Dam Eye Study. American Journal of Public Health. 1992;82(12):1658- 1662. https://doi.org/10.2105/AJPH.82.12.1658
  29. Kim HJ, Park JW, Joo CH. An epidemiological study of the risk factors associated with anterior polar cataract. J Korean Ophthalmol Soc. 2003;44(3):606-614.
  30. Pask SS, Lee EH, Paek DM, Cho SI. Body mass index compared with waist circumference indicators as a predictor of elevated intraocular pressure. J Korean Oph Opt Soc. 2010;15(3):293-297.
  31. Tetz MR, O'Morchoe DJ, Gwin TD, Wilbrandt TH, Solomon KD, Hansen SO, et al. Posterior capsular opacification and intraocular lens decentration. Part II: Experimental findings on a prototype circular intraocular lens design. J Cataract Refract Surg. 1988;14(6):614-623. https://doi.org/10.1016/S0886-3350(88)80028-2