갑상선 수질암으로 오인된 갑상선 부신경절종 1예

Paraganglioma of the Thyroid Gland Mimicking Medullary Thyroid Carcinoma

  • 이상연 (서울대학교 의과대학 분당서울대학교병원 이비인후과학교실) ;
  • 이원용 (서울대학교 의과대학 분당서울대학교병원 이비인후과학교실) ;
  • 정우진 (서울대학교 의과대학 분당서울대학교병원 이비인후과학교실) ;
  • 안순현 (서울대학교 의과대학 분당서울대학교병원 이비인후과학교실)
  • Lee, Sang Yeon (Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University College of Medicine, Seoul National University Bundang Hospital) ;
  • Lee, Won Yong (Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University College of Medicine, Seoul National University Bundang Hospital) ;
  • Jeong, Woo-Jin (Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University College of Medicine, Seoul National University Bundang Hospital) ;
  • Ahn, Soon-Hyun (Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University College of Medicine, Seoul National University Bundang Hospital)
  • 투고 : 2012.11.01
  • 심사 : 2012.11.14
  • 발행 : 2012.11.30

초록

Paraganglioma of the thyroid is a neuroendocrine tumor originating from the neural crest. To our knowledge, only 32 cases of thyroid paraganglioma(TP) have been reported to date. TP is difficult to distinguish from medullary thyroid cancer(MTC), hence correct diagnosis is seldom obtained preoperatively. Although immunohistochemistry is helpful for confirmation of TP, these markers are not specific for differential diagnosis between TP and MTC. Therefore, an index of suspicion is important when encountered with MTC with unusual features, or given pathology with neuroendocrine features and unusual immunohistochemical findings. The authors report a case of TP misdiagnosed as MTC at preoperative work-up and intraoperative frozen section analysis, with a review of the literature. The case depicts various immunohistochemical characteristics of the tumor.

키워드

참고문헌

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