약학회지 (YAKHAK HOEJI)

  • 제56권5호
  • /
  • Pages.314-319
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  • 2012
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  • 0377-9556(pISSN)
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  • 2383-9457(eISSN)
대한약학회 (The Pharmaceutical Society of Korea)
권호 표지

들쭉 추출물의 노인성 황반변성증 예방 효과

Protective Effect of Vaccinium uliginosum L. Extract on Age-related Macular Degeneration

  • 투고 : 2012.08.10
  • 심사 : 2012.10.30
  • 발행 : 2012.10.31
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⟨ 이전 논문 다음 논문 ⟩

초록

Age-related macular degeneration (AMD) is the leading cause of vision loss and blindness among the elderly. In this study, extract of Vaccinium uliginosum L. that has potent antioxidant activity was evaluated as effective preventive supplement for AMD using AMD animal model induced by high fat diet and UV A irradiation. Treatment with VU extract protected photoreceptor cells of retina and blocked the accumulation of lipofuscin pigment-granules induced by high fat diet and UV A light irradiation. This study suggests that VU extract may be a useful agent for prevention of progress of AMD.

키워드

참고문헌

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