Clinical and Experimental Reproductive Medicine

  • 제39권4호
  • /
  • Pages.161-165
  • /
  • 2012
  • /
  • 2233-8233(pISSN)
  • /
  • 2233-8241(eISSN)
대한생식의학회 (The Korean Society for Reproductive Medicine)
권호 표지
DOI QR코드

DOI QR Code

Hysterosalpingo-contrast sonography: is possible to quantify the therapeutic effect of a diagnostic test?

  • Giugliano, Emilio (Department of Biomedical Sciences and Advanced Therapies, University of Ferrara) ;
  • Cagnazzo, Elisa (Department of Biomedical Sciences and Advanced Therapies, University of Ferrara) ;
  • Bazzan, Elisa (Department of Biomedical Sciences and Advanced Therapies, University of Ferrara) ;
  • Patella, Alfredo (Department of Biomedical Sciences and Advanced Therapies, University of Ferrara) ;
  • Marci, Roberto (Department of Biomedical Sciences and Advanced Therapies, University of Ferrara)
  • 투고 : 2012.09.13
  • 심사 : 2012.10.31
  • 발행 : 2012.12.31
PDF 다운로드
⟨ 이전 논문 다음 논문 ⟩

초록

Objective: To evaluate the effect of hysterosalpingo-contrast sonography (HyCoSy) on natural conception in the infertile patient. Methods: We conducted a prospective observational study recruiting 180 patients admitted to Infertility Center of Ferrara University from January 2010 to February 2012. The essential inclusion criteria was the couple's desire to perform only diagnostic evaluation on infertility causes and to wait for natural conception before proceeding with further management. Couples were investigated with hormonal profile, semen analysis and HyCoSy. Expected time for spontaneous pregnancy was 180 days from HyCoSy. First datation sonography of pregnancy was used calculating time elapsed from HyCoSy at conception. Results: Forty patients (22.2%) obtained spontaneous pregnancy within 6 months after HyCoSy. The mean of "conception time" was 75 days. The pregnancy rate was significantly higher in the first 30 days (45%) compared to other the months of observation (p<0.0005). Multiple linear regression analysis showed that maternal age and sterility duration proved independent variables in detecting the "conception time" after HyCoSy (t=3.742, p=0.001, t=2.371, p=0.02, respectively). Conclusion: A possible beneficial effect of HyCoSy is feasible especially in the days following its execution. This temporal correlation supports its therapeutic use.

키워드

참고문헌

  1. Zegers-Hochschild F, Adamson GD, de Mouzon J, Ishihara O, Mansour R, Nygren K, et al. International Committee for Monitoring Assisted Reproductive Technology (ICMART) and the World Health Organization (WHO) revised glossary of ART terminology, 2009. Fertil Steril 2009;92:1520-4. https://doi.org/10.1016/j.fertnstert.2009.09.009
  2. Das S, Nardo LG, Seif MW. Proximal tubal disease: the place for tubal cannulation. Reprod Biomed Online 2007;15:383-8. https://doi.org/10.1016/S1472-6483(10)60362-8
  3. ESHRE Capri Workshop Group. Diagnosis and management of the infertile couple: missing information. Hum Reprod Update 2004;10:295-307. https://doi.org/10.1093/humupd/dmh024
  4. Wahby O, Sobrero AJ, Epstein JA. Hysterosalpingography in relation to pregnancy and its outcome in infertile women. Fertil Steril 1966;17:520-30. https://doi.org/10.1016/S0015-0282(16)36010-1
  5. Nugent D, Watson AJ, Killick SR, Balen AH, Rutherford AJ. A randomized controlled trial of tubal flushing with lipiodol for unexplained infertility. Fertil Steril 2002;77:173-5. https://doi.org/10.1016/S0015-0282(01)02925-9
  6. Lindborg L, Thorburn J, Bergh C, Strandell A. Influence of HyCoSy on spontaneous pregnancy: a randomized controlled trial. Hum Reprod 2009;24:1075-9. https://doi.org/10.1093/humrep/den485
  7. Luciano DE, Exacoustos C, Johns DA, Luciano AA. Can hysterosalpingo- contrast sonography replace hysterosalpingography in confirming tubal blockage after hysteroscopic sterilization and in the evaluation of the uterus and tubes in infertile patients? Am J Obstet Gynecol 2011;204:79.e1-5.
  8. Cao XW, Lin K, Li CY, Yuan CW. A review of WHO laboratory manual for the examination and processing of human semen (5th edition). Zhonghua Nan Ke Xue 2011;17:1059-63.
  9. Luttjeboer F, Harada T, Hughes E, Johnson N, Lilford R, Mol BW. Tubal flushing for subfertility. Cochrane Database Syst Rev 2007; (3):CD003718.
  10. Chenia F, Hofmeyr GJ, Moolla S, Oratis P. Sonographic hydrotubation using agitated saline: a new technique for improving fallopian tube visualization. Br J Radiol 1997;70:833-6. https://doi.org/10.1259/bjr.70.836.9486049
  11. Hamed HO, Shahin AY, Elsamman AM. Hysterosalpingo-contrast sonography versus radiographic hysterosalpingography in the evaluation of tubal patency. Int J Gynaecol Obstet 2009;105:215-7. https://doi.org/10.1016/j.ijgo.2009.02.001
  12. Simpson WL Jr, Beitia LG, Mester J. Hysterosalpingography: a reemerging study. Radiographics 2006;26:419-31. https://doi.org/10.1148/rg.262055109
  13. Noorhasan D, Heard MJ. Gadolinium radiologic contrast is a useful alternative for hysterosalpingography in patients with iodine allergy. Fertil Steril 2005;84:1744.
  14. Saunders RD, Shwayder JM, Nakajima ST. Current methods of tubal patency assessment. Fertil Steril 2011;95:2171-9. https://doi.org/10.1016/j.fertnstert.2011.02.054
  15. Zain MM, Norman RJ. Impact of obesity on female fertility and fertility treatment. Womens Health (Lond Engl) 2008;4:183-94. https://doi.org/10.2217/17455057.4.2.183

피인용 문헌

  1. Hysterosalpingocontrast sonography (HyCoSy): evaluation of the pain perception, side effects and complications vol.13, pp.None, 2012, https://doi.org/10.1186/1471-2342-13-28
  2. The role of Hysterosalpingo-contrast sonography in the evaluation of tubal patency and uterine cavity pathology in infertile women vol.23, pp.5, 2012, https://doi.org/10.17116/repro201723548-53
  3. Assessment of the Influence on Spontaneous Pregnancy of Hysterosalpingo-Contrast Sonography vol.2018, pp.None, 2012, https://doi.org/10.1155/2018/4901281
  4. Clinical Aspects of HyFoSy as Tubal Patency Test in Subfertility Workup vol.2019, pp.None, 2012, https://doi.org/10.1155/2019/4827376
  5. Tubal Flushing Treatment for Unexplained Infertility vol.38, pp.1, 2012, https://doi.org/10.1055/s-0040-1721720
  6. Does hysterosalpingo-foam sonography have any therapeutic effect? A systematic review vol.72, pp.1, 2012, https://doi.org/10.23736/s0026-4784.20.04514-1
  7. Lipiodol flush under ultrasound guidance in Australia vol.60, pp.6, 2012, https://doi.org/10.1111/ajo.13244
  8. Spontaneous conception outcome in infertile women after four-dimensional hysterosalpingo-contrast-sonography vol.20, pp.1, 2020, https://doi.org/10.1186/s12884-020-03315-x