Tuberculosis and Respiratory Diseases

The Korean Academy of Tuberculosis and Respiratory Diseases (대한결핵및호흡기학회)
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A Case of Pulmonary MALT Lymphoma Arising from Lymphocytic Interstitial Pneumonitis

  • Park, Ki Hoon (Department of Internal Medicine, Bucheon St. Mary's Hospital, The Catholic University of Korea School of Medicine) ;
  • Kwon, Soon Seog (Department of Internal Medicine, Bucheon St. Mary's Hospital, The Catholic University of Korea School of Medicine) ;
  • Chung, Myung Hee (Department of Radiology, Bucheon St. Mary's Hospital, The Catholic University of Korea School of Medicine) ;
  • Kim, Jeana (Department of Pathology, Bucheon St. Mary's Hospital, The Catholic University of Korea School of Medicine) ;
  • Lee, Hee Jung (Department of Pathology, Bucheon St. Mary's Hospital, The Catholic University of Korea School of Medicine) ;
  • Min, Ji-Won (Department of Internal Medicine, Catholic Medical Center, The Catholic University of Korea School of Medicine) ;
  • Kim, Yong Hyun (Department of Internal Medicine, Bucheon St. Mary's Hospital, The Catholic University of Korea School of Medicine)
  • Received : 2012.04.09
  • Accepted : 2012.04.26
  • Published : 2012.08.30
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Abstract

Pulmonary mucosa-associated lymphoid tissue-derived (MALT) lymphoma is a rare disease. This disorder is considered to be a model of antigen-driven lymphoma, which is driven either by autoantigens or by chronic inflammatory conditions. Low-grade B-cell MALT lymphoma may develop from a nonneoplastic pulmonary lymphoproliferative disorder, such as lymphocytic interstitial pneumonitis (LIP). A recent estimate predicts that less than 5% of LIP patients acquire malignant, low-grade, B-cell lymphoma. In Korea, there has been no previous report of malignant low-grade, B-cell lymphoma, acquired from LIP. Here, we present the case of a patient with LIP that developed into pulmonary MALT lymphoma, six years after diagnosis.

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References

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