Tuberculosis and Respiratory Diseases

The Korean Academy of Tuberculosis and Respiratory Diseases (대한결핵및호흡기학회)
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Bacterial Pathogens of Ventilator Associated Pneumonia in a Tertiary Referral Hospital

  • Chi, Su Young (Department of Internal Medicine, Chonnam National University Medical School) ;
  • Kim, Tae Ok (Department of Internal Medicine, Chonnam National University Medical School) ;
  • Park, Chan Woo (Department of Internal Medicine, Chonnam National University Medical School) ;
  • Yu, Jin Yeong (Department of Internal Medicine, Chonnam National University Medical School) ;
  • Lee, Boram (Department of Internal Medicine, Chonnam National University Medical School) ;
  • Lee, Ho Sung (Department of Internal Medicine, Chonnam National University Medical School) ;
  • Kim, Yu Il (Department of Internal Medicine, Chonnam National University Medical School) ;
  • Lim, Sung Chul (Department of Internal Medicine, Chonnam National University Medical School) ;
  • Kwon, Yong Soo (Department of Internal Medicine, Chonnam National University Medical School)
  • Received : 2012.03.21
  • Accepted : 2012.05.30
  • Published : 2012.07.30
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Abstract

Background: This study evaluates the bacterial pathogens of Ventilator-associated pneumonia (VAP) in a tertiary referral hospital. Methods: A total of 109 bacterial pathogens from 91 adult patients with VAP, who were admitted to the medical intensive care unit from January 2008 to December 2009, were examined. Clinical characteristics, bacterial pathogens, and resistance profiles were analyzed. Results: Staphylococcus aureus (44%) was the most frequently isolated. Acinetobacter baumanii (30%), Pseudomonas aeruginosa (12%), Stenotrophomonas maltophilia (7%), Klebsiella pneumoniae (6%), and Serratia marcescens (2%) were isolated from the transtracheal aspirates or bronchoalveolar lavage in patients with VAP. There was no significant difference of bacterial pathogens between early and late onset VAP. All isolated S. aureus were methicillin resistant S. aureus; the imipenem resistance rate of A. baumanii was 69%. Conclusion: The two most frequent pathogens of VAP were S. aureus and A. baumanii. There were no pathogenic differences between early and late onset VAP.

Keywords

Acknowledgement

Supported by : Chonnam National University Hospital

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